The oral Ca/calmodulin‐dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure

A modified approach for programmed electrical stimulation in mice: Inducibility of ventricular arrhythmias

(2018) Lukas Clasen et al.   PLoS One

CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis

(2017) Amanda C. Doran et al.   JOURNAL OF CLINICAL INVESTIGATION

CaMKII as a target for arrhythmia suppression

(2017) Julian Mustroph et al.   PHARMACOLOGY & THERAPEUTICS

Role of CaMKII in cardiac arrhythmias

(2015) Thomas J. Hund et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Generation and Behavior Characterization of CaMKIIβ Knockout Mice

(2014) Adam D. Bachstetter et al.   PLoS One

CaMKII inhibitors: from research tools to therapeutic agents

(2014) Patricia Pellicena et al.   Frontiers in Pharmacology

CaMKII regulation of cardiac K channels

(2014) Julian Mustroph et al.   Frontiers in Pharmacology

Novel aspects of excitation–contraction coupling in heart failure

(2013) Stefan Neef et al.   BASIC RESEARCH IN CARDIOLOGY

Ca 2+ /Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially Regulate Sarcoplasmic Reticulum Ca 2+ Leak in Human Cardiac Pathology

(2013) Thomas H. Fischer et al.   CIRCULATION

Crucial Role for Ca 2+ /Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation

(2013) Nazha Hamdani et al.   CIRCULATION RESEARCH

Mechanisms of Altered Ca 2+ Handling in Heart Failure

(2013) Min Luo et al.   CIRCULATION RESEARCH

Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease

(2013) Karl Toischer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

(2013) Jeffrey R. Erickson et al.   NATURE

Enhanced Sarcoplasmic Reticulum Ca 2+ Leak and Increased Na + -Ca 2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation

(2012) Niels Voigt et al.   CIRCULATION

Reactive Oxygen Species–Activated Ca/Calmodulin Kinase IIδ Is Required for Late I Na Augmentation Leading to Cellular Na and Ca Overload

(2011) Stefan Wagner et al.   CIRCULATION RESEARCH

CaMKII in myocardial hypertrophy and heart failure

(2011) Mark E. Anderson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytes

(2011) Jabe M. Best et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Tachycardia-Induced Diastolic Dysfunction and Resting Tone in Myocardium From Patients With a Normal Ejection Fraction

(2011) Donald E. Selby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Differential Cardiac Remodeling in Preload Versus Afterload

(2010) Karl Toischer et al.   CIRCULATION

Inhibition of Elevated Ca 2+ /Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium

(2010) Samuel Sossalla et al.   CIRCULATION RESEARCH

CaMKII-Dependent Diastolic SR Ca 2+ Leak and Elevated Diastolic Ca 2+ Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation

(2010) Stefan Neef et al.   CIRCULATION RESEARCH

Epidemiology and risk profile of heart failure

(2010) Anh L. Bui et al.   Nature Reviews Cardiology

Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents

(2009) Stefan Wagner et al.   Circulation-Arrhythmia and Electrophysiology

Calcium/Calmodulin-Dependent Protein Kinase II Contributes to Cardiac Arrhythmogenesis in Heart Failure

(2009) Can M. Sag et al.   Circulation-Heart Failure

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION