Merit of an Ursodeoxycholic Acid Clinical Trial in COVID-19 Patients

Ursodeoxycholic acid attenuates the expression of proinflammatory cytokines in periodontal cells

(2020) Reza Talebian et al.   JOURNAL OF PERIODONTOLOGY

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

(2020) James T. England et al.   BLOOD REVIEWS

COVID-19 infection: the perspectives on immune responses

(2020) Yufang Shi et al.   CELL DEATH AND DIFFERENTIATION

The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China

(2020) Wen Zhang et al.   CLINICAL IMMUNOLOGY

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

(2020) Mehmet Soy et al.   CLINICAL RHEUMATOLOGY

Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19

(2020) Yang Yang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

From mice to monkeys, animals studied for coronavirus answers

(2020) Jon Cohen   SCIENCE

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

(2020) Brandi N. Williamson et al.   NATURE

Ursodeoxycholic Acid Regulates Hepatic Energy Homeostasis and White Adipose Tissue Macrophages Polarization in Leptin-Deficiency Obese Mice

(2019) Yu-Sheng Chen et al.   Cells

Ursodeoxycholic acid stimulates alveolar fluid clearance in LPS‐induced pulmonary edema via ALX/cAMP/PI3K pathway

(2019) Fangfang Niu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ursodeoxycholic acid: A promising therapeutic target for inflammatory bowel diseases?

(2019) Stephen Joseph Keely et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Bile acid metabolites control TH17 and Treg cell differentiation

(2019) Saiyu Hang et al.   NATURE

Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis

(2019) Xinyang Song et al.   NATURE

Ursodeoxycholic Acid Inhibits Inflammatory Responses and Promotes Functional Recovery After Spinal Cord Injury in Rats

(2018) Wan-Kyu Ko et al.   MOLECULAR NEUROBIOLOGY

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

(2018) Aran Singanayagam et al.   Nature Communications

Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages

(2017) Wan-Kyu Ko et al.   PLoS One

Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome

(2016) Chuansheng Guo et al.   IMMUNITY

Oral Solubilized Ursodeoxycholic Acid Therapy in Amyotrophic Lateral Sclerosis: A Randomized Cross-Over Trial

(2012) Ju-Hong Min et al.   JOURNAL OF KOREAN MEDICAL SCIENCE