Myocyte-derived Myomaker expression is required for regenerative fusion but exacerbates membrane instability in dystrophic myofibers

How cells fuse

(2019) Nicolas G. Brukman et al.   JOURNAL OF CELL BIOLOGY

Muscular dystrophies

(2019) Eugenio Mercuri et al.   LANCET

Cell Fusion: Merging Membranes and Making Muscle

(2019) Michael J. Petrany et al.   TRENDS IN CELL BIOLOGY

MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice

(2018) Yann S Gallot et al.   HUMAN MOLECULAR GENETICS

Myoblast fusion confusion: the resolution begins

(2018) Srihari C. Sampath et al.   Skeletal Muscle

Myomaker and Myomerger Work Independently to Control Distinct Steps of Membrane Remodeling during Myoblast Fusion

(2018) Evgenia Leikina et al.   DEVELOPMENTAL CELL

Control of muscle formation by the fusogenic micropeptide myomixer

(2017) Pengpeng Bi et al.   SCIENCE

Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications

(2017) Antonio L. Serrano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration

(2017) Giuliana Rossi et al.   Nature Communications

Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development

(2017) Malgorzata E. Quinn et al.   Nature Communications

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy

(2017) Qingnian Goh et al.   eLife

Defective membrane fusion and repair inAnoctamin5-deficient muscular dystrophy

(2016) Danielle A. Griffin et al.   HUMAN MOLECULAR GENETICS

COUP-TFII regulates satellite cell function and muscular dystrophy

(2016) Xin Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure–function analysis of myomaker domains required for myoblast fusion

(2016) Douglas P. Millay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Satellite Cells in Muscular Dystrophy – Lost in Polarity

(2016) Natasha C. Chang et al.   TRENDS IN MOLECULAR MEDICINE

Thrombospondin expression in myofibers stabilizes muscle membranes

(2016) Davy Vanhoutte et al.   eLife

Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration

(2016) Addolorata Pisconti et al.   Skeletal Muscle

Mechanisms of myoblast fusion during muscle development

(2015) Ji Hoon Kim et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Myomaker, Regulated by MYOD, MYOG and miR-140-3p, Promotes Chicken Myoblast Fusion

(2015) Wen Luo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division

(2015) Nicolas A Dumont et al.   NATURE MEDICINE

Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia

(2015) William Duddy et al.   Skeletal Muscle

Myomaker mediates fusion of fast myocytes in zebrafish embryos

(2014) Aurélie Landemaine et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy

(2014) C. Jiang et al.   Disease Models & Mechanisms

Myomaker is essential for muscle regeneration

(2014) Douglas P. Millay et al.   GENES & DEVELOPMENT

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

(2014) Matthew Timothy Tierney et al.   NATURE MEDICINE

Cellular and molecular mechanisms underlying muscular dystrophy

(2013) Fedik Rahimov et al.   JOURNAL OF CELL BIOLOGY

Myomaker is a membrane activator of myoblast fusion and muscle formation

(2013) Douglas P. Millay et al.   NATURE

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

(2011) M. M. Murphy et al.   DEVELOPMENT

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle

(2011) Sanjeewa A. Goonasekera et al.   JOURNAL OF CLINICAL INVESTIGATION

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

(2010) Alessandra Sacco et al.   CELL

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells

(2010) Francesco Saverio Tedesco et al.   JOURNAL OF CLINICAL INVESTIGATION

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

(2009) Christoph Lepper et al.   NATURE