Exercise hormone irisin mitigates endothelial barrier dysfunction and microvascular leakage–related diseases

Acute Respiratory Distress Syndrome

(2018) Eddy Fan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Irisin inhibits pancreatic cancer cell growth via the AMPK-mTOR pathway

(2018) Jiayu Liu et al.   Scientific Reports

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

(2018) Hyeonwoo Kim et al.   CELL

Physiology and role of irisin in glucose homeostasis

(2017) Nikolaos Perakakis et al.   Nature Reviews Endocrinology

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury

(2017) Ken Chen et al.   Science Translational Medicine

Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit

(2016) Jing Liu et al.   EMBO Molecular Medicine

Transendothelial migration: unifying principles from the endothelial perspective

(2016) William A. Muller   IMMUNOLOGICAL REVIEWS

Irisin Inhibits Hepatic Cholesterol Synthesis via AMPK-SREBP2 Signaling

(2016) Hong Tang et al.   EBioMedicine

Irisin improves fatty acid oxidation and glucose utilization in type 2 diabetes by regulating the AMPK signaling pathway

(2015) C Xin et al.   INTERNATIONAL JOURNAL OF OBESITY

Mitochondrial mechanisms of endothelial dysfunction

(2015) Adam Szewczyk et al.   Pharmacological Reports

Inhibition of AMP-Activated Protein Kinase Accentuates Lipopolysaccharide-Induced Lung Endothelial Barrier Dysfunction and Lung Injury in Vivo

(2013) Junjie Xing et al.   AMERICAN JOURNAL OF PATHOLOGY

Depleted energy charge and increased pulmonary endothelial permeability induced by mitochondrial complex I inhibition are mitigated by coenzyme Q1 in the isolated perfused rat lung

(2013) Robert D. Bongard et al.   FREE RADICAL BIOLOGY AND MEDICINE

Irisin is inversely associated with intrahepatic triglyceride contents in obese adults

(2013) Hui-Jie Zhang et al.   JOURNAL OF HEPATOLOGY

Exercise Training for Refractory Angina: Improving the Coronary Collateral Circulation

(2012) Georg Froehlich et al.   CARDIOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Absence of Integrin αvβ3 Enhances Vascular Leak in Mice by Inhibiting Endothelial Cortical Actin Formation

(2011) George Su et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis

(2011) Carlo Viscomi et al.   Cell Metabolism

Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis

(2010) Xiaofeng Zhao et al.   ADVANCED DRUG DELIVERY REVIEWS

VE-cadherin: at the front, center, and sides of endothelial cell organization and function

(2010) Elizabeth S Harris et al.   CURRENT OPINION IN CELL BIOLOGY

Activation and Signaling by the AMP-Activated Protein Kinase in Endothelial Cells

(2009) Beate Fisslthaler et al.   CIRCULATION RESEARCH

Bone Marrow Progenitor Cells Induce Endothelial Adherens Junction Integrity by Sphingosine-1-Phosphate–Mediated Rac1 and Cdc42 Signaling

(2009) Yidan D. Zhao et al.   CIRCULATION RESEARCH

Regulation of Endothelial Junctional Permeability

(2008) Emily Vandenbroucke et al.   Annals of the New York Academy of Sciences

Regulation of transendothelial permeability by Src Kinase

(2008) Guochang Hu et al.   MICROVASCULAR RESEARCH

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS