Targeting epithelium-expressed sialyl Lewis glycans improves colonic mucosal wound healing and protects against colitis

Barley β-glucan accelerates wound healing by favoring migration versus proliferation of human dermal fibroblasts

(2019) N.P. Fusté et al.   CARBOHYDRATE POLYMERS

Polysaccharide from Scutellaria baicalensis Georgi ameliorates colitis via suppressing NF-κB signaling and NLRP3 inflammasome activation

(2019) Li Cui et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Elucidation of the mechanism underlying CD44v6-induced transformation of IEC-6 normal intestinal epithelial cells

(2019) Shin-Yi Chung et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Plasma N -Glycan Signatures Associate With Features of Inflammatory Bowel Diseases

(2018) Florent Clerc et al.   GASTROENTEROLOGY

Estrogen Receptor-Alpha (ESR1) Governs the Lower Female Reproductive Tract Vulnerability to Candida albicans

(2018) Laura Salinas-Muñoz et al.   Frontiers in Immunology

Contribution of Wound-Associated Cells and Mediators in Orchestrating Gastrointestinal Mucosal Wound Repair

(2018) Miguel Quirós et al.   Annual Review of Physiology

Crosstalk between Raf-MEK-ERK and PI3K-Akt-GSK3β signaling networks promotes chemoresistance, invasion/migration and stemness via expression of CD44 variants (v4 and v6) in oral cancer

(2018) Tanushree Kashyap et al.   ORAL ONCOLOGY

Astragalus polysaccharides protect against dextran sulfate sodium-induced colitis by inhibiting NF-κВ activation

(2017) Jun Lv et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

(2017) Miguel Quiros et al.   JOURNAL OF CLINICAL INVESTIGATION

Wound healing effect of an Astragalus membranaceus polysaccharide and its mechanism

(2017) Bingjiang Zhao et al.   Molecular Medicine Reports

Epithelial glycosylation in gut homeostasis and inflammation

(2016) Yoshiyuki Goto et al.   NATURE IMMUNOLOGY

 3/4 Fucosyltransferase 3-Dependent Synthesis of Sialyl Lewis A on CD44 Variant Containing Exon 6 Mediates Polymorphonuclear Leukocyte Detachment from Intestinal Epithelium during Transepithelial Migration

(2013) J. C. Brazil et al.   JOURNAL OF IMMUNOLOGY

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Compromised Intestinal Epithelial Barrier Induces Adaptive Immune Compensation that Protects from Colitis

(2012) Manirath Khounlotham et al.   IMMUNITY

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

(2012) Giovanna Leoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Hyaluronan-CD44 interactions as potential targets for cancer therapy

(2011) Suniti Misra et al.   FEBS Journal

Significance of CD44s and CD44v6 Expression in Pancreaticobiliary Maljunction

(2011) Akihiko Tsuchida et al.   HEPATO-GASTROENTEROLOGY

Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation

(2011) Jessica M. Holmn Larsson et al.   INFLAMMATORY BOWEL DISEASES

CD44v6 Coordinates Tumor Matrix-triggered Motility and Apoptosis Resistance

(2011) Thorsten Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice

(2011) Jianxin Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated Pathway

(2011) Mayumi Jijiwa et al.   PLoS One

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

(2010) Dermot P.B. McGovern et al.   HUMAN MOLECULAR GENETICS

Neutrophil Migration across Intestinal Epithelium: Evidence for a Role of CD44 in Regulating Detachment of Migrating Cells from the Luminal Surface

(2010) J. C. Brazil et al.   JOURNAL OF IMMUNOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Galectin-2 and -4, but not Galectin-1, promote intestinal epithelial wound healing in vitro through a TGF-beta-independent mechanism

(2008) Daniela Paclik et al.   INFLAMMATORY BOWEL DISEASES

CD44 Engagement Promotes Matrix-Derived Survival through the CD44-SRC-Integrin Axis in Lipid Rafts

(2008) J.-L. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Epithelial restitution and wound healing in inflammatory bowel disease

(2008) Andreas Sturm et al.   WORLD JOURNAL OF GASTROENTEROLOGY