MicroRNAs and Their Targetomes in Tumor-Immune Communication

Endoplasmic Reticulum Stress Promotes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate PD-L1 Expression in Macrophages

(2019) Jiatao Liu et al.   HEPATOLOGY

miR-450a acts as a tumor suppressor in ovarian cancer by regulating energy metabolism

(2019) Bruna Rodrigues Muys et al.   CANCER RESEARCH

MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells

(2019) Zhong Zheng et al.   Molecular Cancer

Cancer-Derived Exosomes as Effectors of Key Inflammation-Related Players

(2019) Norahayu Othman et al.   Frontiers in Immunology

miR-448 targets IDO1 and regulates CD8+ T cell response in human colon cancer

(2019) Qiong Lou et al.   Journal for ImmunoTherapy of Cancer

Targeting CD47/TNFAIP8 by miR-155 overcomes drug resistance and inhibits tumor growth through induction of phagocytosis and apoptosis in multiple myeloma

(2019) Nasrin Rastgoo et al.   HAEMATOLOGICA

EBV microRNA-BHRF1-2-5p targets the 3′UTR of immune checkpoint ligands PD-L1 and PD-L2

(2019) Alexandre S. Cristino et al.   BLOOD

MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma

(2019) Virginie Vignard et al.   Cancer Immunology Research

Regulation and Function of the PD-L1 Checkpoint

(2018) Chong Sun et al.   IMMUNITY

Epigenetics and MicroRNAs in Cancer

(2018) Alice Ramassone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy

(2018) Qian Huang et al.   Journal of Hematology & Oncology

Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) Identifies Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Targets in Endothelial Cells

(2018) Lauren A. Gay et al.   JOURNAL OF VIROLOGY

Epstein−Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas

(2018) Eleni Anastasiadou et al.   LEUKEMIA

MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47

(2018) Wei Huang et al.   Molecular Cancer

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

(2018) Naohiro Seo et al.   Nature Communications

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer

(2018) Jieru Zhou et al.   Cancer Immunology Research

The Roles of microRNAs in Regulating the Expression of PD-1/PD-L1 Immune Checkpoint

(2017) Qingshui Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

microRNA target prediction programs predict many false positives

(2016) Natalia Pinzón et al.   GENOME RESEARCH

Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

(2016) Keisuke Kataoka et al.   NATURE

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

(2016) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data

(2016) Yuheng Lu et al.   PLoS Computational Biology

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity

(2015) Buvana Ravishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity

(2015) Michael J. Moore et al.   Nature Communications

MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells

(2015) Kent Riemondy et al.   eLife

Mutant p53 exerts oncogenic effects through microRNAs and their target gene networks

(2014) Xiao Ling Li et al.   FEBS LETTERS

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

Progress and challenge of microRNA research in immunity

(2014) Hyang-Mi Lee et al.   Frontiers in Genetics

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

GCN2-Dependent Metabolic Stress Is Essential for Endotoxemic Cytokine Induction and Pathology

(2013) H. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

(2013) Mark P. Hamilton et al.   Nature Communications

microRNA Biogenesis Pathway as a Therapeutic Target for Human Disease and Cancer

(2012) Francesca De Santa et al.   CURRENT PHARMACEUTICAL DESIGN

Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting

(2012) Gabriel B. Loeb et al.   MOLECULAR CELL

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

(2011) Kentaro Kojima et al.   Nature Communications

Posttranscriptional Upregulation by MicroRNAs

(2011) Shobha Vasudevan   Wiley Interdisciplinary Reviews-RNA

Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia

(2010) Mark P. Chao et al.   CANCER RESEARCH

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

(2009) Sung Wook Chi et al.   NATURE