Human Prostate Cancer Is Characterized by an Increase in Urea Cycle Metabolites

Metabolomic profiling for the identification of novel diagnostic markers and therapeutic targets in prostate cancer: an update

(2019) Giuseppe Lucarelli et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Reprogramming of isocitrate dehydrogenases expression and activity by the androgen receptor in prostate cancer

(2019) Kevin Gonthier et al.   MOLECULAR CANCER RESEARCH

IDH2 reprograms mitochondrial dynamics in cancer through a HIF-1α–regulated pseudohypoxic state

(2019) Yuan Wang et al.   FASEB JOURNAL

Higher prevalence of lymph node metastasis in prostate cancer in patients with diabetes

(2018) Stefan Zoltán Lutz et al.   ENDOCRINE-RELATED CANCER

Metabolomics and transcriptomics profiles reveal the dysregulation of the tricarboxylic acid cycle and related mechanisms in prostate cancer

(2018) Yaping Shao et al.   INTERNATIONAL JOURNAL OF CANCER

Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate

(2018) Haengki Park et al.   LABORATORY INVESTIGATION

NMR-based metabolomics studies of human prostate cancer tissue

(2018) Ana Rita Lima et al.   Metabolomics

Glucose impairments and insulin resistance in prostate cancer: the role of obesity, nutrition and exercise

(2018) K. M. Di Sebastiano et al.   Obesity Reviews

Androgen receptor overexpression in prostate cancer in type 2 diabetes

(2018) Stefan Zoltán Lutz et al.   Molecular Metabolism

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016

(2018) et al.   JAMA Oncology

cGMP-dependent protein kinase I (cGKI) modulates human hepatic stellate cell activation

(2018) Andras Franko et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A distinct plasma lipid signature associated with poor prognosis in castration-resistant prostate cancer

(2017) Hui-Ming Lin et al.   INTERNATIONAL JOURNAL OF CANCER

APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells

(2017) David W. McIlwain et al.   Oncotarget

Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells

(2017) Jiangsha Zhao et al.   Oncotarget

Molecular subtyping of prostate cancer

(2016) Samuel D. Kaffenberger et al.   CURRENT OPINION IN UROLOGY

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice

(2016) Andras Franko et al.   DIABETES

The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target

(2016) Icard Philippe et al.   DRUG RESISTANCE UPDATES

Oncometabolites: Unconventional triggers of oncogenic signalling cascades

(2016) Marco Sciacovelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biomarker Discovery in Human Prostate Cancer: an Update in Metabolomics Studies

(2016) Ana Rita Lima et al.   Translational Oncology

The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma

(2015) Jonathan I. Epstein et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia

(2015) Guro F Giskeødegård et al.   BRITISH JOURNAL OF CANCER

Metabolomic profiling for the identification of novel diagnostic markers in prostate cancer

(2015) Giuseppe Lucarelli et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Integration of Metabolomics and Transcriptomics Reveals Major Metabolic Pathways and Potential Biomarker Involved in Prostate Cancer

(2015) Shancheng Ren et al.   MOLECULAR & CELLULAR PROTEOMICS

Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

(2014) V. Zecchini et al.   EMBO JOURNAL

The Oncometabolite Fumarate Promotes Pseudohypoxia Through Noncanonical Activation of NF-κB Signaling

(2014) Karthigayan Shanmugasundaram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer Metabolism and ElevatedO-GlcNAc in Oncogenic Signaling

(2014) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of Urinary Pseudotargeted LC-MS-Based Metabolomics Method and Its Application in Hepatocellular Carcinoma Biomarker Discovery

(2014) Yaping Shao et al.   JOURNAL OF PROTEOME RESEARCH

Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography/mass spectrometry

(2013) Shili Chen et al.   JOURNAL OF CHROMATOGRAPHY A

Oncometabolites: linking altered metabolism with cancer

(2013) Ming Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Spermine and Citrate as Metabolic Biomarkers for Assessing Prostate Cancer Aggressiveness

(2013) Guro F. Giskeødegård et al.   PLoS One

Metabolomic signatures of aggressive prostate cancer

(2013) Jonathan E. McDunn et al.   PROSTATE

Changes in Gene Transcription Underlying the Aberrant Citrate and Choline Metabolism in Human Prostate Cancer Samples

(2012) H. Bertilsson et al.   CLINICAL CANCER RESEARCH

Inhibition of  -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

(2012) M. Xiao et al.   GENES & DEVELOPMENT

The emerging role of fumarate as an oncometabolite

(2012) Ming Yang et al.   Frontiers in Oncology

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using1H HR-MAS spectroscopy of biopsy tissues

(2008) May-Britt Tessem et al.   MAGNETIC RESONANCE IN MEDICINE