Characterization of Glycolysis-Associated Molecules in the Tumor Microenvironment Revealed by Pan-Cancer Tissues and Lung Cancer Single Cell Data

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

(2020) Pearl Lee et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stiffer Matrix Accelerates Migration of Hepatocellular Carcinoma Cells through Enhanced Aerobic Glycolysis Via the MAPK-YAP Signaling

(2020) Qiu-Ping Liu et al.   Cancers

Molecular landmarks of tumor hypoxia across cancer types

(2019) Vinayak Bhandari et al.   NATURE GENETICS

Metabolic regulation of cell growth and proliferation

(2019) Jiajun Zhu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

A positive feedback loop between Myc and aerobic glycolysis sustains tumor growth in a Drosophila tumor model

(2019) Kenneth Kin Lam Wong et al.   eLife

The Immune Landscape of Cancer

(2019) Vésteinn Thorsson et al.   IMMUNITY

Visual and volumetric parameters by 18F-FDG-PET/CT: a head to head comparison for the prediction of outcome in patients with multiple myeloma

(2019) Rosa Fonti et al.   ANNALS OF HEMATOLOGY

The reactome pathway knowledgebase

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Genomic and Functional Approaches to Understanding Cancer Aneuploidy

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Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

(2018) Ling Li et al.   CANCER CELL

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

(2018) Jianfang Liu et al.   CELL

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

(2018) Tina Cascone et al.   Cell Metabolism

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Phenotype molding of stromal cells in the lung tumor microenvironment

(2018) Diether Lambrechts et al.   NATURE MEDICINE

18F-FDG PET intensity correlates with a hypoxic gene signature and other oncogenic abnormalities in operable non-small cell lung cancer

(2018) Brendan T. Heiden et al.   PLoS One

Cell-Autonomous Metabolic Reprogramming in Hypoxia

(2018) Luana Schito et al.   TRENDS IN CELL BIOLOGY

Roles of Aldolase Family Genes in Human Cancers and Diseases

(2018) Yu-Chan Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

(2018) Xinxin Peng et al.   Cell Reports

Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

(2018) Patrick Danaher et al.   Journal for ImmunoTherapy of Cancer

Positron emission tomography 18F-fluorodeoxyglucose uptake correlates with KRAS and EMT gene signatures in operable esophageal adenocarcinoma

(2018) Brendan T. Heiden et al.   JOURNAL OF SURGICAL RESEARCH

A pan-cancer study of copy number gain and up-regulation in human oncogenes

(2018) YongKiat Wee et al.   LIFE SCIENCES

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The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer

(2018) Wei Jiang et al.   Journal of Hematology & Oncology

The collagen prolyl hydroxylases are bifunctional growth regulators in melanoma

(2018) Aithne Atkinson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review)

(2018) Youbang Xie et al.   Molecular Medicine Reports

Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

(2018) S. R. Rosario et al.   Nature Communications

Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance

(2018) Gaofeng Xiong et al.   Nature Communications

Effect of Mutant p53 Proteins on Glycolysis and Mitochondrial Metabolism

(2017) Matilda Eriksson et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

(2017) Grant M. Fischer et al.   Pigment Cell & Melanoma Research

GLUT1 regulates cell glycolysis and proliferation in prostate cancer

(2017) Hengjun Xiao et al.   PROSTATE

Fueling the Cell Division Cycle

(2017) María Salazar-Roa et al.   TRENDS IN CELL BIOLOGY

Mitochondrial respiratory gene expression is suppressed in many cancers

(2017) Ed Reznik et al.   eLife

Web-TCGA: an online platform for integrated analysis of molecular cancer data sets

(2016) Mario Deng et al.   BMC BIOINFORMATICS

An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma

(2016) A. Ari Hakimi et al.   CANCER CELL

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma

(2016) K. Tateishi et al.   CLINICAL CANCER RESEARCH

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

(2016) Bernard Thienpont et al.   NATURE

TP53 mutation hits energy metabolism and increases glycolysis in breast cancer

(2016) Hajnalka Harami-Papp et al.   Oncotarget

Tumors and Mitochondrial Respiration: A Neglected Connection

(2015) Andrea Viale et al.   CANCER RESEARCH

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression

(2015) Zhaoyong Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aerobic Glycolysis as a Marker of Tumor Aggressiveness: Preliminary Data in High Grade Human Brain Tumors

(2015) Andrei G. Vlassenko et al.   DISEASE MARKERS

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression

(2015) Joshua C. Black et al.   GENES & DEVELOPMENT

The Clinical Significance of Hypoxia in Human Cancers

(2015) Neesha Dhani et al.   SEMINARS IN NUCLEAR MEDICINE

MYC, Metabolism, and Cancer

(2015) Z. E. Stine et al.   Cancer Discovery

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

(2014) Gaofeng Xiong et al.   BMC CANCER

Hexokinase 2 regulates G1/S checkpoint through CDK2 in cancer-associated fibroblasts

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GSVA: gene set variation analysis for microarray and RNA-Seq data

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Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis

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Heterogeneity of tumor-induced gene expression changes in the human metabolic network

(2013) Jie Hu et al.   NATURE BIOTECHNOLOGY

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

The Expression of Glyceraldehyde-3-Phosphate Dehydrogenase Associated Cell Cycle (GACC) Genes Correlates with Cancer Stage and Poor Survival in Patients with Solid Tumors

(2013) Dunrui Wang et al.   PLoS One

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Molecular signatures database (MSigDB) 3.0

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Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene

(2010) F M Buffa et al.   BRITISH JOURNAL OF CANCER

18F-FDG Uptake in Lung, Breast, and Colon Cancers: Molecular Biology Correlates and Disease Characterization

(2009) H. Jadvar et al.   JOURNAL OF NUCLEAR MEDICINE

E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

(2009) A. Almeida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Mitochondria in cancer: Not just innocent bystanders

(2008) Christian Frezza et al.   SEMINARS IN CANCER BIOLOGY