Impact of Short-Term Hypoxia on Sirtuins as Regulatory Elements in HUVECs

Increased serum levels of advanced glycation end products due to induced molting in hen layers trigger a proinflammatory response by peripheral blood leukocytes

(2020) Yossi Wein et al.   POULTRY SCIENCE

Impact of Nutrition on Short-Term Exercise-Induced Sirtuin Regulation: Vegans Differ from Omnivores and Lacto-Ovo Vegetarians

(2020) Arne Björn Potthast et al.   Nutrients

Cardiac Rehabilitation and Endothelial Function

(2020) Gaetano Antonio Lanza et al.   Journal of Clinical Medicine

Resveratrol and Vascular Function

(2019) Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exercise and Sirtuins: A Way to Mitochondrial Health in Skeletal Muscle

(2019) Katya Vargas-Ortiz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of vitamin D in cell-cell interaction of fetal endothelial progenitor cells and umbilical cord endothelial cells in a preeclampsia-like model

(2019) L. Brodowski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging

(2019) Andy W. C. Man et al.   Frontiers in Physiology

SIRT2: Controversy and multiple roles in disease and physiology

(2019) Yan Wang et al.   AGEING RESEARCH REVIEWS

Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases

(2018) Maria Angela Incalza et al.   VASCULAR PHARMACOLOGY

Sirtuins and NAD + in the Development and Treatment of Metabolic and Cardiovascular Diseases

(2018) Alice E. Kane et al.   CIRCULATION RESEARCH

Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease

(2018) Xiaochen He et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Vascular ageing: Underlying mechanisms and clinical implications

(2017) Ageliki Laina et al.   EXPERIMENTAL GERONTOLOGY

Multi-regulatory network of ROS: the interconnection of ROS, PGC-1 alpha, and AMPK-SIRT1 during exercise

(2017) Anand Thirupathi et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency

(2017) Arne Björn Potthast et al.   PLoS One

Mitochondrial function in hypoxic ischemic injury and influence of aging

(2017) P. Benson Ham et al.   PROGRESS IN NEUROBIOLOGY

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

(2016) Natalie E. de Picciotto et al.   AGING CELL

The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis

(2016) Munehiro Kitada et al.   Aging-US

Sirtuins, Cell Senescence, and Vascular Aging

(2016) Yujiro Kida et al.   CANADIAN JOURNAL OF CARDIOLOGY

Sirt4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity

(2016) Yu-Xuan Luo et al.   EUROPEAN HEART JOURNAL

HELLP Syndrome

(2016) Mareike Sandvoß et al.   Reproductive Sciences

SIRT1 performs a balancing act on the tight-rope toward longevity

(2016) Aparna Purushotham et al.   Aging-US

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK

(2016) Linh Ho et al.   Aging-US

The sirtuins, oxidative stress and aging: an emerging link

(2016) Philip I. Merksamer et al.   Aging-US

From ATP to PTP and Back: A Dual Function for the Mitochondrial ATP Synthase

(2015) P. Bernardi et al.   CIRCULATION RESEARCH

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

(2015) Stephan Winnik et al.   EUROPEAN HEART JOURNAL

SIRT1 attenuates severe ischemic damage by preserving cerebral blood flow

(2015) Yorito Hattori et al.   NEUROREPORT

Gestational diabetes induces alterations of sirtuins in fetal endothelial cells

(2015) Juan Gui et al.   PEDIATRIC RESEARCH

NAD+ in aging, metabolism, and neurodegeneration

(2015) E. Verdin   SCIENCE

The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice

(2014) Lindsey B. Gano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia

(2014) Anne H.-H. Tseng et al.   BIOCHEMICAL JOURNAL

SIRT4 Suppresses Inflammatory Responses in Human Umbilical Vein Endothelial Cells

(2014) Yu Tao et al.   Cardiovascular Toxicology

Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity

(2014) Rommel A. Mathias et al.   CELL

Mitochondrial protein acetylation regulates metabolism

(2014) Kristin A. Anderson et al.   Essays in Biochemistry

Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase

(2014) Yorito Hattori et al.   STROKE

Physiological and pathological functions of NADPH oxidases during myocardial ischemia–reperfusion

(2014) Shouji Matsushima et al.   TRENDS IN CARDIOVASCULAR MEDICINE

NAD+ and sirtuins in aging and disease

(2014) Shin-ichiro Imai et al.   TRENDS IN CELL BIOLOGY

Mitochondria, endothelial cell function, and vascular diseases

(2014) Xiaoqiang Tang et al.   Frontiers in Physiology

SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase

(2013) Gaëlle Laurent et al.   MOLECULAR CELL

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA

(2012) Yu-Ting Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling

(2012) Rui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin Catalysis and Regulation

(2012) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Protective roles of SIRT1 in atherosclerosis

(2011) Sokrates Stein et al.   CELL CYCLE

Hypoxia Increases Sirtuin 1 Expression in a Hypoxia-inducible Factor-dependent Manner

(2011) Rui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans

(2011) Anthony J. Donato et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

(2010) Agnieszka A. Kendrick et al.   BIOCHEMICAL JOURNAL

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

FoxO1 Mediates an Autofeedback Loop Regulating SIRT1 Expression

(2010) Shiqin Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fasting promotes the expression of SIRT1, an NAD+-dependent protein deacetylase, via activation of PPARα in mice

(2010) Satoru Hayashida et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1

(2010) Masato Iwabu et al.   NATURE

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

SIRT1 is regulated by a PPARγ–SIRT1 negative feedback loop associated with senescence

(2010) Limin Han et al.   NUCLEIC ACIDS RESEARCH

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

Preeclampsia and HELLP Syndrome: Impaired Mitochondrial Function in Umbilical Endothelial Cells

(2010) Sabine Illsinger et al.   Reproductive Sciences

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

NAD+, Sirtuins, and Cardiovascular Disease

(2009) Nica Borradaile et al.   CURRENT PHARMACEUTICAL DESIGN

COUP-TFII is Regulated by High Glucose in Endothelial Cells

(2009) C. Brunssen et al.   HORMONE AND METABOLIC RESEARCH

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

(2008) Q.-j. Zhang et al.   CARDIOVASCULAR RESEARCH

Endotheliale Dysfunktion: Pathophysiologie, Diagnostik und prognostische Bedeutung

(2008) T Münzel   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA