Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

(2010) Jianjun Bao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice

(2010) Carlos Escande et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Succinyl-CoA Ligase Deficiency: A Mitochondrial Hepatoencephalomyopathy

(2010) Johan L K Van Hove et al.   PEDIATRIC RESEARCH

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Calorie restriction alters mitochondrial protein acetylation

(2009) Bjoern Schwer et al.   AGING CELL

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

Sympathoexcitation by Oxidative Stress in the Brain Mediates Arterial Pressure Elevation in Obesity-Induced Hypertension

(2009) Ai Nagae et al.   CIRCULATION

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxo1 integrates insulin signaling with mitochondrial function in the liver

(2009) Zhiyong Cheng et al.   NATURE MEDICINE

Surrogate Alcohols and Their Metabolites Modify Histone H3 Acetylation: Involvement of Histone Acetyl Transferase and Histone Deacetylase

(2008) Mahua Choudhury et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Minireview: Mitochondrial Energetics and Insulin Resistance

(2008) Anthony E. Civitarese et al.   ENDOCRINOLOGY

Mitochondrial Dysfunction in Type 2 Diabetes and Obesity

(2008) Kurt Højlund et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Oxidative Inactivation of Key Mitochondrial Proteins Leads to Dysfunction and Injury in Hepatic Ischemia Reperfusion

(2008) Kwan–Hoon Moon et al.   GASTROENTEROLOGY

Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5

(2008) Christine Schlicker et al.   JOURNAL OF MOLECULAR BIOLOGY

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA