Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma

Ultrasensitive immunoprofiling of plasma extracellular vesicles identifies syndecan-1 as a potential tool for minimally invasive diagnosis of glioma

(2019) Vineesh Indira Chandran et al.   CLINICAL CANCER RESEARCH

Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics

(2019) Vineesh Indira Chandran et al.   JOURNAL OF NEURO-ONCOLOGY

Detection of Glioma-Derived Exosomes with the Biotinylated Antibody-Functionalized Titanium Nitride Plasmonic Biosensor

(2018) Guangyu Qiu et al.   ADVANCED FUNCTIONAL MATERIALS

Atomic force microscopy analysis of extracellular vesicles

(2017) P. Parisse et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients

(2017) Javier M Figueroa et al.   NEURO-ONCOLOGY

MicroRNA in Glioblastoma: An Overview

(2017) Barbara Banelli et al.   International Journal of Genomics

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

(2016) Iñigo San-Millán et al.   CARCINOGENESIS

Extracellular Vesicles in Brain Tumor Progression

(2016) Esterina D’Asti et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The biology and function of exosomes in cancer

(2016) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Cancer metabolism: a therapeutic perspective

(2016) Ubaldo E. Martinez-Outschoorn et al.   Nature Reviews Clinical Oncology

Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas

(2016) Vera Miranda-Gonçalves et al.   Oncotarget

DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients

(2016) Noemí García-Romero et al.   Oncotarget

Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance

(2016) Susana Romero-Garcia et al.   Frontiers in Immunology

Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients

(2015) Rui Shi et al.   Oncotarget

Metabolic Targeting of Lactate Efflux by Malignant Glioma Inhibits Invasiveness and Induces Necrosis: An In Vivo Study

(2015) Chaim B Colen et al.   NEOPLASIA

Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival

(2014) C. L. Roland et al.   CANCER RESEARCH

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

An aptasensor using DNA aptamer and white light common-path SPR spectral interferometry to detect cytochrome-c for anti-cancer drug screening

(2014) Fong-Chuen Loo et al.   SENSORS AND ACTUATORS B-CHEMICAL

Extracellular vesicles shed by glioma cells: pathogenic role and clinical value

(2014) Dimitry A. Chistiakov et al.   TUMOR BIOLOGY

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

(2012) Kivanç Birsoy et al.   NATURE GENETICS

The monocarboxylate transporter family-Structure and functional characterization

(2011) Andrew P. Halestrap   IUBMB LIFE

High-resolution atomic force microscopy and spectroscopy of native membrane proteins

(2011) Christian A Bippes et al.   REPORTS ON PROGRESS IN PHYSICS

LSPR-based nanobiosensors

(2009) Borja Sepúlveda et al.   Nano Today

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY