Independent Replication on Genome-Wide Association Study Signals Identifies IRF3 as a Novel Locus for Systemic Lupus Erythematosus

Identification ofST3AGL4,MFHAS1, CSNK2A2andCD226as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning

(2018) Yong-Fei Wang et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

IRF3 and type I interferons fuel a fatal response to myocardial infarction

(2017) Kevin R King et al.   NATURE MEDICINE

Transancestral mapping and genetic load in systemic lupus erythematosus

(2017) Carl D. Langefeld et al.   Nature Communications

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

(2016) David L Morris et al.   NATURE GENETICS

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

(2016) Celi Sun et al.   NATURE GENETICS

Toll-like receptors: potential targets for lupus treatment

(2015) Yan-wei Wu et al.   ACTA PHARMACOLOGICA SINICA

Genome-wide search followed by replication reveals genetic interaction ofCD80andALOX5APassociated with systemic lupus erythematosus in Asian populations

(2015) Yan Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Functional IRF3 deficiency in a patient with herpes simplex encephalitis

(2015) Line Lykke Andersen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

(2015) James Bentham et al.   NATURE GENETICS

Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis

(2015) Chandra Mohan et al.   Nature Reviews Nephrology

Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus

(2015) Yan Zhang et al.   ARTHRITIS RESEARCH & THERAPY

Gene-Based Meta-Analysis of Genome-Wide Association Study Data Identifies Independent Single-Nucleotide Polymorphisms inANXA6as Being Associated With Systemic Lupus Erythematosus in Asian Populations

(2015) Jing Zhang et al.   Arthritis & Rheumatology

Interferon regulatory factor 3 as key element of the interferon signature in plasmacytoid dendritic cells from systemic lupus erythematosus patients: novel genetic associations in the Mexican mestizo population

(2014) K. Santana-de Anda et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus

(2014) Yan Zhang et al.   HUMAN MOLECULAR GENETICS

Innate Antiviral Host Defense Attenuates TGF-β Function through IRF3-Mediated Suppression of Smad Signaling

(2014) Pinglong Xu et al.   MOLECULAR CELL

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

(2014) Gillian I Rice et al.   NATURE GENETICS

Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians

(2012) Wanling Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association Study of IFIH1 rs1990760 Polymorphism with Systemic Lupus Erythematosus in a Chinese Population

(2012) Han Cen et al.   INFLAMMATION

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Autoimmune Disease Risk Variant of IFIH1 Is Associated with Increased Sensitivity to IFN-  and Serologic Autoimmunity in Lupus Patients

(2011) T. Robinson et al.   JOURNAL OF IMMUNOLOGY

Association of CD247 with systemic lupus erythematosus in Asian populations

(2011) R Li et al.   LUPUS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

ELF1 is associated with systemic lupus erythematosus in Asian populations

(2010) J. Yang et al.   HUMAN MOLECULAR GENETICS

Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus

(2010) Wanling Yang et al.   PLoS Genetics

Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese

(2009) W Yang et al.   GENES AND IMMUNITY

No evidence for genetic association of interferon regulatory factor 3 in systemic lupus erythematosus

(2009) E Sánchez et al.   LUPUS

Infections as triggers and complications of systemic lupus erythematosus

(2008) A Doria et al.   AUTOIMMUNITY REVIEWS