Evaluating the Role of CXCR3 in Pain Modulation: A Literature Review

Spinal caspase-6 contributes to remifentanil-induced hyperalgesia via regulating CCL21/CXCR3 pathway in rats

(2020) Chunyan Wang et al.   NEUROSCIENCE LETTERS

C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood–Spinal Cord Barrier

(2020) Hao-Ling Li et al.   Frontiers in Immunology

The Role of CXCR3 in Neurological Diseases

(2019) Ya-Qun Zhou et al.   Current Neuropharmacology

Perioperative opioid analgesia—when is enough too much? A review of opioid-induced tolerance and hyperalgesia

(2019) Lesley A Colvin et al.   LANCET

DMT1 Expression and Iron Levels at the Crossroads Between Aging and Neurodegeneration

(2019) Rosaria Ingrassia et al.   Frontiers in Neuroscience

Genomewide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS-Induced Periodontitis

(2018) Sarah Hiyari et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8+ T Cells but Promotes Colitis via CD4+ T Cells

(2018) Qing-Zhi Liu et al.   Frontiers in Immunology

Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies

(2018) Anna Piotrowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The involvement of iron responsive element (-) divalent metal transporter 1-mediated the spinal iron overload via CXCL10/CXCR3 pathway in neuropathic pain in rats

(2018) Weituan Xu et al.   NEUROSCIENCE LETTERS

Chemokine CXCL10/CXCR3 signaling contributes to neuropathic pain in spinal cord and dorsal root ganglia after chronic constriction injury in rats

(2018) Yonglin Chen et al.   NEUROSCIENCE LETTERS

CXCR3/CXCL10 Axis Regulates Neutrophil–NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis

(2017) Giorgia Benigni et al.   JOURNAL OF IMMUNOLOGY

Potential role of CXCL10/CXCR3 signaling in the development of morphine tolerance in periaqueductal gray

(2017) Wei Wang et al.   NEUROPEPTIDES

Chemokine Receptor CXCR3 in the Spinal Cord Contributes to Chronic Itch in Mice

(2017) Peng-Bo Jing et al.   Neuroscience Bulletin

Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis

(2017) Sandro Altamura et al.   JOURNAL OF ALZHEIMERS DISEASE

Promoted Interaction of C/EBPα with Demethylated Cxcr3 Gene Promoter Contributes to Neuropathic Pain in Mice

(2016) Bao-Chun Jiang et al.   JOURNAL OF NEUROSCIENCE

Predictive model for survival in patients having repeat radiation treatment for painful bone metastases

(2016) Edward Chow et al.   RADIOTHERAPY AND ONCOLOGY

Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis

(2016) Yoshiyuki Akiyama et al.   Scientific Reports

Spinal Peroxynitrite Contributes to Remifentanil-induced Postoperative Hyperalgesia via Enhancement of Divalent Metal Transporter 1 without Iron-responsive Element–mediated Iron Accumulation in Rats

(2015) Rui-Chen Shu et al.   ANESTHESIOLOGY

Chemokines and Their Receptors: Potential Therapeutic Targets for Bone Cancer Pain

(2015) Ya-Qun Zhou et al.   CURRENT PHARMACEUTICAL DESIGN

CXCR3: Latest evidence for the involvement of chemokine signaling in bone cancer pain

(2015) Genhua Guo et al.   EXPERIMENTAL NEUROLOGY

Activation of spinal chemokine receptor CXCR3 mediates bone cancer pain through an Akt-ERK crosstalk pathway in rats

(2015) Xue-Hai Guan et al.   EXPERIMENTAL NEUROLOGY

Current and emerging drugs for interstitial cystitis/bladder pain syndrome (IC/BPS)

(2015) Teruyuki Ogawa et al.   EXPERT OPINION ON EMERGING DRUGS

CXCR3 chemokine receptor signaling mediates itch in experimental allergic contact dermatitis

(2015) Lintao Qu et al.   PAIN

Molecular aspects of the pathogenesis of periodontitis

(2015) Joerg Meyle et al.   PERIODONTOLOGY 2000

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

(2015) J. S. Burg et al.   SCIENCE

Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

(2015) L. Qin et al.   SCIENCE

Nociception and role of immune system in pain

(2014) Vivek Verma et al.   ACTA NEUROLOGICA BELGICA

N-terminal region of human chemokine receptor CXCR3: Structural analysis of CXCR3(1–48) by experimental and computational studies

(2014) R. Raucci et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Osteoarthritis joint pain: The cytokine connection

(2014) Rachel E. Miller et al.   CYTOKINE

Transgenic Expression of CXCR3 on T Cells Enhances Susceptibility to Cutaneous Leishmania major Infection by Inhibiting Monocyte Maturation and Promoting a Th2 Response

(2014) Steve Oghumu et al.   INFECTION AND IMMUNITY

Activation of CXCL10/CXCR3 Signaling Attenuates Morphine Analgesia: Involvement of Gi Protein

(2014) Dawei Ye et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Descending Controls Modulate Inflammatory Joint Pain and Regulate CXC Chemokine and iNOS Expression in the Dorsal Horn

(2014) Fiona B Carr et al.   Molecular Pain

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Spinal IFN-γ-induced protein-10 (CXCL10) mediates metastatic breast cancer-induced bone pain by activation of microglia in rat models

(2013) Huilian Bu et al.   BREAST CANCER RESEARCH AND TREATMENT

Expression of CXCR3 on Specific T Cells Is Essential for Homing to the Prostate Gland in an Experimental Model of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

(2013) M. L. Breser et al.   JOURNAL OF IMMUNOLOGY

Inflammatory and immune pathways in the pathogenesis of periodontal disease

(2013) Ali Cekici et al.   PERIODONTOLOGY 2000

A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection

(2012) Chung-Her Jenh et al.   BMC IMMUNOLOGY

Caries induced cytokine network in the odontoblast layer of human teeth

(2011) Orapin V Horst et al.   BMC IMMUNOLOGY

Caspase signalling controls microglia activation and neurotoxicity

(2011) Miguel A. Burguillos et al.   NATURE

Is CREB the Angry Bird that Releases Memory in Alzheimer's?

(2011) Allan Wang et al.   NEUROPSYCHOPHARMACOLOGY

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

(2010) Jan Bondeson et al.   ARTHRITIS AND RHEUMATISM

Central modulation of pain

(2010) Michael H. Ossipov et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

CXCR3, Inflammation, and Autoimmune Diseases

(2009) Stéphanie Lacotte et al.   Annals of the New York Academy of Sciences

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Catechins Inhibit CCL20 Production in IL-17A-Stimulated Human Gingival Fibroblasts

(2009) Yoshitaka Hosokawa et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-κB in hippocampal neuronal cell culture

(2008) Hilda Bajova et al.   JOURNAL OF NEUROIMMUNOLOGY