The Interactions of Parasite Calreticulin With Initial Complement Components: Consequences in Immunity and Virulence

Utilization of complement receptors in immune cell–microbe interaction

(2020) Szilvia Lukácsi et al.   FEBS LETTERS

Trypanosoma cruzi Calreticulin: Immune Evasion, Infectivity, and Tumorigenesis

(2020) Galia Ramírez-Toloza et al.   TRENDS IN PARASITOLOGY

Chagas disease vaccine design: the search for an efficient Trypanosoma cruzi immune-mediated control

(2020) Augusto E. Bivona et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Trypanosoma carassii infection in goldfish (Carassius auratus L.): changes in the expression of erythropoiesis and anemia regulatory genes

(2019) Mark McAllister et al.   PARASITOLOGY RESEARCH

Calreticulin in phagocytosis and cancer: opposite roles in immune response outcomes

(2019) Alejandro Schcolnik-Cabrera et al.   APOPTOSIS

Role of calreticulin in biotic and abiotic stress signalling and tolerance mechanisms in plants

(2019) Rini Joshi et al.   GENE

Structural bases that underline Trypanosoma cruzi calreticulin proinfective, antiangiogenic and antitumor properties

(2019) Jaime Peña Álvarez et al.   IMMUNOBIOLOGY

The C1q Receptors: Focus on gC1qR/p33 (C1qBP, p32, HABP-1)1

(2019) Berhane Ghebrehiwet et al.   SEMINARS IN IMMUNOLOGY

Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells

(2019) P. Cruz et al.   IMMUNOBIOLOGY

Complement and Complement Targeting Therapies in Glomerular Diseases

(2019) Sofia Andrighetto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metal binding study of calreticulin: An immunomodulatory protein of human filarial parasite Brugia malayi

(2018) Sunita Yadav et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Evaluation of Opisthorchis viverrini calreticulin for potential host modulation

(2018) Wanlapa Chaibangyang et al.   ACTA TROPICA

Different Trypanosoma cruzi calreticulin domains mediate migration and proliferation of fibroblasts in vitro and skin wound healing in vivo

(2018) Jose Ignacio Arias et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Programmed cell removal by calreticulin in tissue homeostasis and cancer

(2018) Mingye Feng et al.   Nature Communications

Entamoeba histolytica: Quantitative Proteomics Analysis Reveals Putative Virulence-Associated Differentially Abundant Membrane Proteins

(2018) Yee Ling Ng et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Entamoeba histolytica Calreticulin Induces the Expression of Cytokines in Peripheral Blood Mononuclear Cells Isolated From Patients With Amebic Liver Abscess

(2018) Enrique Gonzalez Rivas et al.   Frontiers in Cellular and Infection Microbiology

Exogenous Calreticulin, incorporated onto non-infective Trypanosoma cruzi epimastigotes, promotes their internalization into mammal host cells

(2017) Eduardo Sosoniuk-Roche et al.   IMMUNOBIOLOGY

Molecular and Biochemical Characterization of Opisthorchis viverrini Calreticulin

(2017) Wanlapa Chaibangyang et al.   KOREAN JOURNAL OF PARASITOLOGY

SjCRT, a recombinant Schistosoma japonicum calreticulin, induces maturation of dendritic cells and a Th1-polarized immune response in mice

(2017) Lizhen Ma et al.   Parasites & Vectors

Differential expression of pathogenic genes of Entamoeba histolytica vs E. dispar in a model of infection using human liver tissue explants

(2017) Cecilia Ximénez et al.   PLoS One

Trypanosoma cruzi Evades the Complement System as an Efficient Strategy to Survive in the Mammalian Host: The Specific Roles of Host/Parasite Molecules and Trypanosoma cruzi Calreticulin

(2017) Galia Ramírez-Toloza et al.   Frontiers in Microbiology

Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy

(2017) Limei Zhao et al.   Frontiers in Immunology

Triatoma infestans Calreticulin: Gene Cloning and Expression of a Main Domain That Interacts with the Host Complement System

(2016) Katherine Weinberger et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection?

(2016) Paula Abello-Cáceres et al.   BMC CANCER

Dynamic flux of microvesicles modulate parasite-host cell interaction of Trypanosoma cruzi in eukaryotic cells

(2016) M.I. Ramirez et al.   CELLULAR MICROBIOLOGY

Calreticulin, a therapeutic target?

(2016) Paul Eggleton et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cloning, expression, molecular characterization and preliminary studies on immunomodulating properties of recombinant Trypanosoma congolense calreticulin

(2016) Geraldine Bossard et al.   INFECTION GENETICS AND EVOLUTION

Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection

(2016) Mariana S. Cardoso et al.   Frontiers in Immunology

Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties

(2016) Christophe Moreau et al.   IUCrJ

Trypanosoma cruzi Calreticulin Topographical Variations in Parasites Infecting Murine Macrophages

(2015) Andrea González et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

Amblyomma americanum tick calreticulin binds C1q but does not inhibit activation of the classical complement cascade

(2015) Tae Kwon Kim et al.   Ticks and Tick-Borne Diseases

Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation

(2015) Ran Sun et al.   PLoS Neglected Tropical Diseases

Differential ability to resist to complement lysis and invade host cells mediated by MBL in R4 and 860 strains ofTrypanosoma cruzi

(2014) Ingrid Evans-Osses et al.   FEBS LETTERS

Relative Contribution of C1q and Apoptotic Cell-Surface Calreticulin to Macrophage Phagocytosis

(2014) Mélanie Verneret et al.   Journal of Innate Immunity

Trypanosoma cruzi calreticulin inhibits the complement lectin pathway activation by direct interaction with L-Ficolin

(2014) Eduardo Sosoniuk et al.   MOLECULAR IMMUNOLOGY

In Silico and In Vitro Studies on the Protein-Protein Interactions between Brugia malayi Immunomodulatory Protein Calreticulin and Human C1q

(2014) Sunita Yadav et al.   PLoS One

A Monoallelic Deletion of the TcCRT Gene Increases the Attenuation of a Cultured Trypanosoma cruzi Strain, Protecting against an In Vivo Virulent Challenge

(2014) Fernando J. Sánchez-Valdéz et al.   PLoS Neglected Tropical Diseases

Entamoeba histolyticaandE. disparCalreticulin: Inhibition of Classical Complement Pathway and Differences in the Level of Expression in Amoebic Liver Abscess

(2014) Cecilia Ximénez et al.   Biomed Research International

The Interaction of Classical Complement Component C1 with Parasite and Host Calreticulin Mediates Trypanosoma cruzi Infection of Human Placenta

(2013) Christian Castillo et al.   PLoS Neglected Tropical Diseases

Entamoeba histolytica Cell Surface Calreticulin Binds Human C1q and Functions in Amebic Phagocytosis of Host Cells

(2012) Archana Vaithilingam et al.   INFECTION AND IMMUNITY

Calreticulin signaling in health and disease

(2012) Wen-An Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Trypanosoma cruzi Immune Evasion Mediated by Host Cell-Derived Microvesicles

(2012) I. Cestari et al.   JOURNAL OF IMMUNOLOGY

Trypanosoma cruzi carrying a monoallelic deletion of the calreticulin (TcCRT) gene are susceptible to complement mediated killing and defective in their metacyclogenesis

(2012) Fernando J. Sánchez Valdéz et al.   MOLECULAR IMMUNOLOGY

Calreticulin has opposing effects on the migration of human trophoblast and myometrial endothelial cells

(2012) K.E. Crawford et al.   PLACENTA

Extracellular Trypanosoma cruzi calreticulin in the host–parasite interplay

(2011) Galia Ramírez et al.   TRENDS IN PARASITOLOGY

Comparative in vivo antiangiogenic effects of calreticulin from Trypanosoma cruzi and Homo sapiens sapiens

(2010) Victor Toledo et al.   BIOLOGICAL RESEARCH

Trypanosoma cruzi calreticulin: A novel virulence factor that binds complement C1 on the parasite surface and promotes infectivity

(2010) Galia Ramírez et al.   IMMUNOBIOLOGY

Molecular mechanisms involved in the inactivation of the first component of human complement by Trypanosoma cruzi calreticulin

(2010) Carolina Valck et al.   MOLECULAR IMMUNOLOGY

Entamoeba histolytica calreticulin: an endoplasmic reticulum protein expressed by trophozoites into experimentally induced amoebic liver abscesses

(2010) Enrique González et al.   PARASITOLOGY RESEARCH

Antiangiogenic and Antitumor Effects of Trypanosoma cruzi Calreticulin

(2010) Nandy C. López et al.   PLoS Neglected Tropical Diseases

Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum

(2009) Marek Michalak et al.   BIOCHEMICAL JOURNAL

Trypanosoma carassii calreticulin binds host complement component C1q and inhibits classical complement pathway-mediated lysis

(2009) Ayoola Oladiran et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Paths reunited: Initiation of the classical and lectin pathways of complement activation

(2009) Russell Wallis et al.   IMMUNOBIOLOGY

Mapping the complement C1q binding site in Haemonchus contortus calreticulin

(2009) S. Naresha et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi

(2009) Igor dos S. Cestari et al.   MOLECULAR IMMUNOLOGY

Complement C2 Receptor Inhibitor Trispanning Confers an Increased Ability to Resist Complement‐Mediated Lysis inTrypanosoma cruzi

(2008) Igor dos S. Cestari et al.   JOURNAL OF INFECTIOUS DISEASES

Calreticulin in human pregnancy and pre-eclampsia

(2008) V.Y. Gu et al.   MOLECULAR HUMAN REPRODUCTION

Haemonchus contortus calreticulin binds to C-reactive protein of its host, a novel survival strategy of the parasite

(2008) S. SUCHITRA et al.   PARASITE IMMUNOLOGY

Th1-stimulatory polyproteins of soluble Leishmania donovani promastigotes ranging from 89.9 to 97.1kDa offers long-lasting protection against experimental visceral leishmaniasis

(2008) Shraddha Kumari et al.   VACCINE

Complement membrane attack complex formation and infectivity of Trichinella spiralis and T. nativa in rats

(2008) Anu Näreaho et al.   VETERINARY PARASITOLOGY