SGCE Promotes Breast Cancer Stem Cells by Stabilizing EGFR

The single-cell transcriptional landscape of mammalian organogenesis

(2019) Junyue Cao et al.   NATURE

Does the expression of the ACVR2A gene affect the development of colorectal cancer?

(2019) Damian Wodziński et al.   GENETICS AND MOLECULAR BIOLOGY

Extracellular‐signal‐regulated kinase (ERK)/mitogen‐activated protein kinase (MAPK) signaling as a target for cancer therapy: An updated review

(2019) Masoud Najafi et al.   CELL BIOLOGY INTERNATIONAL

SET domain-containing protein 4 epigenetically controls breast cancer stem cell quiescence

(2019) Sen Ye et al.   CANCER RESEARCH

USP22 promotes resistance to EGFR-TKIs by preventing ubiquitination-mediated EGFR degradation in EGFR-mutant lung adenocarcinoma

(2018) Huijuan Zhang et al.   CANCER LETTERS

Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF-1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment

(2018) Haiquan Lu et al.   CANCER RESEARCH

Triple negative breast cancer: Emerging therapeutic modalities and novel combination therapies

(2018) Alice Lee et al.   CANCER TREATMENT REVIEWS

Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling

(2018) Ming Luo et al.   Cell Metabolism

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

(2018) Tianyi Wang et al.   Cell Metabolism

Transcriptional profiles of different states of cancer stem cells in triple-negative breast cancer

(2018) Mingshan Liu et al.   Molecular Cancer

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting Breast Cancer Stem Cells to Overcome Treatment Resistance

(2018) Sònia Palomeras et al.   MOLECULES

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq

(2018) Mihriban Karaayvaz et al.   Nature Communications

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

OUP accepted manuscript

(2017)   NUCLEIC ACIDS RESEARCH

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

(2017) Suhas V Vasaikar et al.   NUCLEIC ACIDS RESEARCH

A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer

(2017) Paul Savage et al.   Cell Reports

In vitro cancer cell–ECM interactions inform in vivo cancer treatment

(2016) Andrew W. Holle et al.   ADVANCED DRUG DELIVERY REVIEWS

Understanding EGFR Signaling in Breast Cancer and Breast Cancer Stem Cells: Overexpression and Therapeutic Implications

(2016) Ibrahim O Alanazi et al.   Asian Pacific Journal of Cancer Prevention

Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgf /Smad Signaling

(2016) S. K. Yeo et al.   CANCER RESEARCH

Endocytic control of signaling at the plasma membrane

(2016) Elisa Barbieri et al.   CURRENT OPINION IN CELL BIOLOGY

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

(2016) Linda S. Steelman et al.   CURRENT PHARMACEUTICAL DESIGN

High-definition CpG methylation of novel genes in gastric carcinogenesis identified by next-generation sequencing

(2016) Jorge L Sepulveda et al.   MODERN PATHOLOGY

SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling

(2016) Zuzana Koledova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype

(2016) Feimeng Zheng et al.   Nature Communications

Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines

(2016) Radosław Januchowski et al.   Journal of Cancer

Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling

(2015) X Tang et al.   CELL DEATH AND DIFFERENTIATION

A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells

(2015) Cheng Chang et al.   GENES & DEVELOPMENT

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

(2015) Haiquan Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focal adhesion signaling and therapy resistance in cancer

(2015) Iris Eke et al.   SEMINARS IN CANCER BIOLOGY

Cancer Stem Cell-Like Phenotype and Survival Are Coordinately Regulated by Akt/FoxO/Bim Pathway

(2015) Ricardo Gargini et al.   STEM CELLS

Epidermal growth factor/heat shock protein 27 pathway regulates vasculogenic mimicry activity of breast cancer stem/progenitor cells

(2014) Che-Hsin Lee et al.   BIOCHIMIE

Correlation between epidermal growth factor receptor and tumor stem cell markers CD44/CD24 and their relationship with prognosis in breast invasive ductal carcinoma

(2014) Zhousan Zheng et al.   MEDICAL ONCOLOGY

TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

(2014) M Bartucci et al.   ONCOGENE

Cancer stem cell differentiation: TGFβ1 and versican may trigger molecules for the organization of tumor spheroids

(2014) G. OKTEM et al.   ONCOLOGY REPORTS

Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts

(2014) Suling Liu et al.   Stem Cell Reports

Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

(2013) J. M. Balko et al.   CANCER RESEARCH

Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell-like Properties in Cancer Cells

(2013) K. Shien et al.   CANCER RESEARCH

Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting

(2013) Yue Sun et al.   DEVELOPMENTAL CELL

Threshold-controlled ubiquitination of the EGFR directs receptor fate

(2013) Sara Sigismund et al.   EMBO JOURNAL

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Effect of adding gefitinib to neoadjuvant chemotherapy in estrogen receptor negative early breast cancer in a randomized phase II trial

(2011) Mogens Bernsdorf et al.   BREAST CANCER RESEARCH AND TREATMENT

Mesenchymal stem cells from primary breast cancer tissue promote cancer proliferation and enhance mammosphere formation partially via EGF/EGFR/Akt pathway

(2011) Xin-long Yan et al.   BREAST CANCER RESEARCH AND TREATMENT

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

(2011) Lisa von Kleist et al.   CELL

Membrane Proteins: The Key Players of a Cancer Cell

(2011) Kim R. Kampen   JOURNAL OF MEMBRANE BIOLOGY

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR

(2011) Trever G. Bivona et al.   NATURE

Plxdc2 Is a Mitogen for Neural Progenitors

(2011) Suzanne F. C. Miller-Delaney et al.   PLoS One

PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

(2009) M. L. Sos et al.   CANCER RESEARCH

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Invasive ductal carcinoma of the breast with the “triple-negative” phenotype: prognostic implications of EGFR immunoreactivity

(2008) Giuseppe Viale et al.   BREAST CANCER RESEARCH AND TREATMENT

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Endocytosis and intracellular trafficking of ErbBs

(2008) Alexander Sorkin et al.   EXPERIMENTAL CELL RESEARCH

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

(2008) D L Wheeler et al.   ONCOGENE

Myoclonus–dystonia syndrome: Clinical presentation, disease course, and genetic features in 11 families

(2007) Nardo Nardocci et al.   MOVEMENT DISORDERS