A potential role for Galectin-3 inhibitors in the treatment of COVID-19

Arguments in favor of remdesivir for treating SARS-CoV-2 infections

(2020) Wen-Chien Ko et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

The epidemiology, diagnosis and treatment of COVID-19

(2020) Pan Zhai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection

(2020) Jacques Fantini et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review

(2020) V. Montalvan et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19

(2020) Carlo Perricone et al.   JOURNAL OF AUTOIMMUNITY

Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19

(2020) Kishan P. Patel et al.   JOURNAL OF CLINICAL VIROLOGY

Structural basis for human coronavirus attachment to sialic acid receptors

(2019) M. Alejandra Tortorici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Role of Galectins in Virus Infection - A Systemic Literature Review

(2019) Wen-Hung Wang et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Pharmacotherapy and adjunctive treatment for idiopathic pulmonary fibrosis (IPF)

(2019) Shigeki Saito et al.   Journal of Thoracic Disease

Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathway

(2019) Zhouliang Ren et al.   BIOSCIENCE REPORTS

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension

(2019) Naga Chalasani et al.   GASTROENTEROLOGY

Expression of 9-O- and 7,9-O-Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses

(2019) Karen N. Barnard et al.   mBio

Galectin-3 Enhances Avian H5N1 Influenza A Virus–Induced Pulmonary Inflammation by Promoting NLRP3 Inflammasome Activation

(2018) Yu-Jung Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment

(2018) María T. Elola et al.   CELLULAR IMMUNOLOGY

Galectin-3 is an amplifier of the interleukin-1β -mediated inflammatory response in corneal keratinocytes

(2018) Yuichi Uchino et al.   IMMUNOLOGY

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

(2017) Wentao Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interference

(2015) Swey-Shen Chen et al.   CELLULAR IMMUNOLOGY

Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca2+influx

(2015) Gusheng Wu et al.   JOURNAL OF NEUROCHEMISTRY

Galectin-3 inhibitors: a patent review (2008–present)

(2014) Helen Blanchard et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies

(2014) Fang Li   JOURNAL OF VIROLOGY

Crystal Structure of Bovine Coronavirus Spike Protein Lectin Domain

(2012) Guiqing Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor

(2011) G. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways

(2009) Andrew Filer et al.   ARTHRITIS AND RHEUMATISM