7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway

7-Hydroxycoumarin protects against cisplatin-induced acute kidney injury by inhibiting necroptosis and promoting Sox9-mediated tubular epithelial cell proliferation

(2020) Wei-Feng Wu et al.   PHYTOMEDICINE

Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene

(2020) Shulin Cheng et al.   MEDICAL SCIENCE MONITOR

Overexpression of peptidase inhibitor 16 attenuates angiotensin II–induced cardiac fibrosis via regulating HDAC1 of cardiac fibroblasts

(2020) Mengqing Deng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

β-hydroxybutyrate attenuates renal ischemia-reperfusion injury through its anti-pyroptotic effects

(2019) Takaya Tajima et al.   KIDNEY INTERNATIONAL

Umbelliferone Ameliorates CCl4-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling

(2019) Ayman M. Mahmoud et al.   INFLAMMATION

Tetramethylpyrazine guards against cisplatin-induced nephrotoxicity in rats through inhibiting HMGB1/TLR4/NF-κB and activating Nrf2 and PPAR-γ signaling pathways

(2019) Haidy E. Michel et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of umbelliferone on adjuvant-induced arthritis in rats by MAPK/NF-κB pathway

(2019) Liu Ouyang et al.   Drug Design Development and Therapy

METTL3/m6A/miRNA-873-5p Attenuated Oxidative Stress and Apoptosis in Colistin-Induced Kidney Injury by Modulating Keap1/Nrf2 Pathway

(2019) Jian Wang et al.   Frontiers in Pharmacology

Sirt5 Attenuates Cisplatin-Induced Acute Kidney Injury through Regulation of Nrf2/HO-1 and Bcl-2

(2019) Wei Li et al.   Biomed Research International

Renoprotective effects of umbelliferone on methotrexate-induced renal injury through regulation of Nrf-2/Keap-1, P 38 MAPK/NF-κB, and apoptosis signaling pathways

(2018) Emad H.M. Hassanein et al.   FOOD AND CHEMICAL TOXICOLOGY

The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells

(2018) Jie Yang et al.   MOLECULAR CARCINOGENESIS

Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response

(2018) Yoshikazu Miyasato et al.   Scientific Reports

Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study

(2018) Ritesh Aggarwal et al.   Annals of Clinical Microbiology and Antimicrobials

Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response

(2017) Chongshan Dai et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

HDAC7 Ubiquitination by the E3 Ligase CBX4 Is Involved in Contextual Fear Conditioning Memory Formation

(2017) Xu Jing et al.   JOURNAL OF NEUROSCIENCE

The protective effect of umbelliferone ameliorates myocardial injury following ischemia‑reperfusion in the rat through suppression NLRP3 inflammasome and upregulating the PPAR-γ

(2017) Hongbo Luo et al.   Molecular Medicine Reports

Screening and identification of key biomarkers in hepatocellular carcinoma: Evidence from bioinformatic analysis

(2017) Lin Li et al.   ONCOLOGY REPORTS

Suppression of BMP-7 by histone deacetylase 2 promoted apoptosis of renal tubular epithelial cells in acute kidney injury

(2017) Taotao Ma et al.   Cell Death & Disease

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling

(2017) Min Liu et al.   Nature Communications

Activation of β1-adrenoceptor triggers oxidative stress mediated myocardial membrane destabilization in isoproterenol induced myocardial infarcted rats: 7-hydroxycoumarin and its counter action

(2016) Govindan Sangaran Jagadeesh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Histone deacetylase–mediated silencing of AMWAP expression contributes to cisplatin nephrotoxicity

(2016) Punithavathi Ranganathan et al.   KIDNEY INTERNATIONAL

Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats

(2015) Govindan Sangaran Jagadeesh et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Gut Bacteria Products Prevent AKI Induced by Ischemia-Reperfusion

(2015) V. Andrade-Oliveira et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Umbelliferone ameliorates cerebral ischemia–reperfusion injury via upregulating the PPAR gamma expression and suppressing TXNIP/NLRP3 inflammasome

(2015) Xiangxiang Wang et al.   NEUROSCIENCE LETTERS

Lycopene Attenuates Colistin-Induced Nephrotoxicity in Mice via Activation of the Nrf2/HO-1 Pathway

(2014) Chongshan Dai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin-Induced Nephrotoxicity in Mice Involves the Mitochondrial, Death Receptor, and Endoplasmic Reticulum Pathways

(2014) Chongshan Dai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy

(2014) Xiaojie Wang et al.   KIDNEY INTERNATIONAL

Coumarins reduce biofilm formation and the virulence of Escherichia coli O157:H7

(2014) Jin-Hyung Lee et al.   PHYTOMEDICINE

Higher Incidence of Acute Kidney Injury With Intravenous Colistimethate Sodium Compared With Polymyxin B in Critically Ill Patients at a Tertiary Care Medical Center

(2013) Darowan S. Akajagbor et al.   CLINICAL INFECTIOUS DISEASES

Role of Nrf2 in protection against acute kidney injury

(2013) Luke M. Shelton et al.   KIDNEY INTERNATIONAL

The Nrf2 pathway in the progression of renal disease

(2013) C. Zoja et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Incidence and predictors of acute kidney injury associated with intravenous polymyxin B therapy

(2012) Christine J. Kubin et al.   JOURNAL OF INFECTION