Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation throughout mRNA lifespan with most impact on short tails

MicroRNAs Cause Accelerated Decay of Short-Tailed Target mRNAs

(2020) Timothy J. Eisen et al.   MOLECULAR CELL

The Dynamics of Cytoplasmic mRNA Metabolism

(2020) Timothy J. Eisen et al.   MOLECULAR CELL

LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA

(2019) Isabel Cruz-Gallardo et al.   NUCLEIC ACIDS RESEARCH

Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase

(2019) Ingmar B. Schäfer et al.   CELL

Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation

(2019) Tobias Raisch et al.   Nature Communications

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

(2018) Michael W. Webster et al.   MOLECULAR CELL

PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay

(2018) Hyerim Yi et al.   MOLECULAR CELL

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Tales of Detailed Poly(A) Tails

(2018) Angela L. Nicholson et al.   TRENDS IN CELL BIOLOGY

Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts

(2017) Sabine Hergovits et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Short poly(A) tails are a conserved feature of highly expressed genes

(2017) Sarah Azoubel Lima et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

(2017) Chyi-Ying A. Chen et al.   RNA

Emerging Themes in Regulation of Global mRNA Turnover in cis

(2017) Chyi-Ying A. Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Short poly(A) tails are a conserved feature of highly expressed genes

(2017) Sarah Azoubel Lima et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives

(2017) Richard J. Maraia et al.   Wiley Interdisciplinary Reviews-RNA

LARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protection

(2017) Sandy Mattijssen et al.   eLife

mRNA length-sensing in eukaryotic translation: reconsidering the “closed loop” and its implications for translational control

(2016) Mary K. Thompson et al.   CURRENT GENETICS

Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV

(2016) Wenshi Wang et al.   Scientific Reports

LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner

(2015) Sandy Mattijssen et al.   MOLECULAR AND CELLULAR BIOLOGY

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

The “tale” of poly(A) binding protein: The MLLE domain and PAM2-containing proteins

(2014) Jingwei Xie et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Determinants and implications of mRNA poly(A) tail size – Does this protein make my tail look big?

(2014) Aimee L. Jalkanen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular Basis of DNA Recognition in the Immune System

(2013) M. K. Atianand et al.   JOURNAL OF IMMUNOLOGY

Predicting the molecular complexity of sequencing libraries

(2013) Timothy Daley et al.   NATURE METHODS

Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin

(2013) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets

(2012) Eric Huntzinger et al.   NUCLEIC ACIDS RESEARCH

La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability

(2010) R. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of deadenylation-dependent decay

(2010) Chyi-Ying A. Chen et al.   Wiley Interdisciplinary Reviews-RNA

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

(2009) Marc R. Fabian et al.   MOLECULAR CELL