Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate

(2016) Chih-Hong Lou et al.   Stem Cell Reports

mRNA deadenylation by Pan2–Pan3: Figure 1

(2014) Jana Wolf et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Uridylation by TUT4 and TUT7 Marks mRNA for Degradation

(2014) Jaechul Lim et al.   CELL

Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation

(2014) J. Wolf et al.   EMBO JOURNAL

Quantifying mRNA targeting to P-bodies in living human cells reveals their dual role in mRNA decay and storage

(2014) Adva Aizer et al.   JOURNAL OF CELL SCIENCE

The structure of the Pan2–Pan3 core complex reveals cross-talk between deadenylase and pseudokinase

(2014) Ingmar B Schäfer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay

(2014) Stefanie Jonas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA decay machines: Deadenylation by the Ccr4–Not and Pan2–Pan3 complexes

(2013) Elmar Wahle et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

BRIC-seq: A genome-wide approach for determining RNA stability in mammalian cells

(2013) Naoto Imamachi et al.   METHODS

Structure of the PAN3 Pseudokinase Reveals the Basis for Interactions with the PAN2 Deadenylase and the GW182 Proteins

(2013) Mary Christie et al.   MOLECULAR CELL

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

(2013) K.-L. Huang et al.   RNA

Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC

(2012) Virginia Castilla-Llorente et al.   JOURNAL OF CELL BIOLOGY

Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm

(2012) Milan Spasic et al.   PLoS Genetics

GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets

(2011) Joerg E. Braun et al.   MOLECULAR CELL

miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs

(2011) Marina Chekulaeva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation

(2011) D. Zheng et al.   RNA

Mechanisms of deadenylation-dependent decay

(2010) Chyi-Ying A. Chen et al.   Wiley Interdisciplinary Reviews-RNA

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

(2009) Marc R. Fabian et al.   MOLECULAR CELL

Decapping is preceded by 3′ uridylation in a novel pathway of bulk mRNA turnover

(2009) Olivia S Rissland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ago–TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

(2009) Chyi-Ying A Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

(2008) Dinghai Zheng et al.   JOURNAL OF CELL BIOLOGY

Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation

(2008) Y. Zhai et al.   MOLECULAR AND CELLULAR BIOLOGY

The Control of mRNA Decapping and P-Body Formation

(2008) Tobias M. Franks et al.   MOLECULAR CELL