Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice

Imbalance in mitochondrial dynamics induced by low PGC-1α expression contributes to hepatocyte EMT and liver fibrosis

(2020) Linzhong Zhang et al.   Cell Death & Disease

Mito-TEMPO, a mitochondria-targeted antioxidant, prevents N-nitrosodiethylamine-induced hepatocarcinogenesis in mice

(2019) Sachin Shetty et al.   FREE RADICAL BIOLOGY AND MEDICINE

Isocitrate dehydrogenase 2 deficiency exacerbates dermis damage by ultraviolet-B via ΔNp63 downregulation

(2018) Hyeong Jun Ku et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Myeloid derived-suppressor cells: their role in cancer and obesity

(2018) Suzanne Ostrand-Rosenberg   CURRENT OPINION IN IMMUNOLOGY

Inflammatory mechanisms linking obesity and metabolic disease

(2017) Alan R. Saltiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolically Healthy Obesity and the Development of Nonalcoholic Fatty Liver Disease

(2016) Yoosoo Chang et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells in mice

(2016) Masato Ogura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

(2016) Chi Ma et al.   NATURE

Metabolically healthy obesity and NAFLD

(2016) Giovanni Targher et al.   Nature Reviews Gastroenterology & Hepatology

S100A8/A9: From basic science to clinical application

(2016) Monika Pruenster et al.   PHARMACOLOGY & THERAPEUTICS

Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction

(2016) Euy‐Myoung Jeong et al.   Journal of the American Heart Association

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice

(2015) Jia-yuan Wu et al.   ACTA PHARMACOLOGICA SINICA

Vicious Inducible Nitric Oxide Synthase-Mitochondrial Reactive Oxygen Species Cycle Accelerates Inflammatory Response and Causes Liver Injury in Rats

(2015) Adelheid Weidinger et al.   ANTIOXIDANTS & REDOX SIGNALING

Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Is Marked by a Higher Frequency of Th17 Cells in the Liver and an Increased Th17/Resting Regulatory T Cell Ratio in Peripheral Blood and in the Liver

(2015) Monika Rau et al.   JOURNAL OF IMMUNOLOGY

Obesity Triggers Enhanced MDSC Accumulation in Murine Renal Tumors via Elevated Local Production of CCL2

(2015) Malika Hale et al.   PLoS One

The Inflammasome in Liver Injury and Non-Alcoholic Fatty Liver Disease

(2014) Wajahat Zafar Mehal   DIGESTIVE DISEASES

Pathological Features of Fatty Liver Disease

(2014) Matthew M. Yeh et al.   GASTROENTEROLOGY

Roles for Chemokines in Liver Disease

(2014) Fabio Marra et al.   GASTROENTEROLOGY

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation

(2014) Wen Liang et al.   LABORATORY INVESTIGATION

Increased monocytic CD14+HLADRlow/− myeloid-derived suppressor cells in obesity

(2014) YI BAO et al.   Molecular Medicine Reports

Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice

(2013) Angelina Mouralidarane et al.   HEPATOLOGY

Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH

(2013) Salvatore Sutti et al.   HEPATOLOGY

In Vitro and in Vivo Models of Non-Alcoholic Fatty Liver Disease (NAFLD)

(2013) Giridhar Kanuri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

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(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

The burden of liver disease in Europe: A review of available epidemiological data

(2013) Martin Blachier et al.   JOURNAL OF HEPATOLOGY

Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1

(2013) A. R. Jackson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

(2013) Annika Mehlem et al.   Nature Protocols

S100A9 a new marker for monocytic human myeloid-derived suppressor cells

(2012) Fei Zhao et al.   IMMUNOLOGY

Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients

(2011) Paola Filipazzi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid derived suppressor cells in human diseases

(2011) Tim F. Greten et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOD1 and MitoTEMPO partially prevent mitochondrial permeability transition pore opening, necrosis, and mitochondrial apoptosis after ATP depletion recovery

(2010) Huan Ling Liang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Immature myeloid cells induced by a high-fat diet contribute to liver inflammation

(2009) Zhong-bin Deng et al.   HEPATOLOGY

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

(2009) E. Maury et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE