POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

(2020) Anke Loregger et al.   Nature Communications

Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins

(2019) Jian Xiao et al.   Science China-Life Sciences

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Mechanisms and regulation of cholesterol homeostasis

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Retrospective on Cholesterol Homeostasis: The Central Role of Scap

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Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

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Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends

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The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

(2017) Jian Wei et al.   Cell Reports

Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol

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The Role of Cholesterol in Cancer

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Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

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Mechanism of Folding and Activation of Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P)

(2015) Joel Ramos da Palma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus

(2015) Daqian Xu et al.   Nature Communications

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

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Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)

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Zymogen Activation and Subcellular Activity of Subtilisin Kexin Isozyme 1/Site 1 Protease

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Relative acidic compartment volume as a lysosomal storage disorder–associated biomarker

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Improved vectors and genome-wide libraries for CRISPR screening

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Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

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The biology and therapeutic targeting of the proprotein convertases

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A Key Enzyme in the Biogenesis of Lysosomes Is a Protease That Regulates Cholesterol Metabolism

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The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Sterol-sensing Endoplasmic Reticulum (ER) Membrane Protein TRC8 Hampers ER to Golgi Transport of Sterol Regulatory Element-binding Protein-2 (SREBP-2)/SREBP Cleavage-activated Protein and Reduces SREBP-2 Cleavage

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