Long noncoding RNA functionality in imprinted domain regulation

Genomic imprinting disorders: lessons on how genome, epigenome and environment interact

(2019) David Monk et al.   NATURE REVIEWS GENETICS

Genomic Imprinting and Physiological Processes in Mammals

(2019) Valter Tucci et al.   CELL

lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

(2019) Megan D. Schertzer et al.   MOLECULAR CELL

The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes

(2019) Daniel Andergassen et al.   PLoS Genetics

Decrypting noncoding RNA interactions, structures, and functional networks

(2019) Muller Fabbri et al.   GENOME RESEARCH

Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway

(2019) Tina Uroda et al.   MOLECULAR CELL

Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF

(2019) Anders S. Hansen et al.   MOLECULAR CELL

RNA Interactions Are Essential for CTCF-Mediated Genome Organization

(2019) Ricardo Saldaña-Meyer et al.   MOLECULAR CELL

Xist RNA in action: Past, present, and future

(2019) Agnese Loda et al.   PLoS Genetics

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

(2018) Saqib S. Sachani et al.   Nature Communications

A mouse model of angelman syndrome imprinting defects

(2018) Michael W Lewis et al.   HUMAN MOLECULAR GENETICS

Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2

(2018) Chringma Sherpa et al.   NUCLEIC ACIDS RESEARCH

Overexpression of microRNAs from the Gtl2-Rian locus contributes to postnatal death in mice

(2017) Soichiro Kumamoto et al.   HUMAN MOLECULAR GENETICS

Long Noncoding RNA MEG3 Is an Epigenetic Determinant of Oncogenic Signaling in Functional Pancreatic Neuroendocrine Tumor Cells

(2017) Sucharitha Iyer et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines

(2017) Xueyin Wang et al.   MOLECULAR CELL

How do lncRNAs regulate transcription?

(2017) Yicheng Long et al.   Science Advances

Expressed alleles of imprinted IGF2, DLK1 and MEG3 colocalize in 3D-preserved nuclei of porcine fetal cells

(2016) Yvette Lahbib-Mansais et al.   BMC CELL BIOLOGY

Establishment and functions of DNA methylation in the germline

(2016) Kathleen R Stewart et al.   Epigenomics

Regulation of DLK1 by the maternally expressed miR-379/miR-544 cluster may underlie callipyge polar overdominance inheritance

(2015) Yun-Qian Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2

(2015) Chen Davidovich et al.   RNA

Decreased expression of MEG3 contributes to retinoblastoma progression and affects retinoblastoma cell growth by regulating the activity of Wnt/β-catenin pathway

(2015) Yali Gao et al.   TUMOR BIOLOGY

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

Unveiling the hidden function of long non-coding RNA by identifying its major partner-protein

(2015) Yongfang Yang et al.   Cell and Bioscience

Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

(2015) Stuti Mehta et al.   PLoS One

LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis

(2014) Sha He et al.   BIOINFORMATICS

ICR Noncoding RNA Expression Controls Imprinting and DNA Replication at the Dlk1-Dio3 Domain

(2014) Satya K. Kota et al.   DEVELOPMENTAL CELL

The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation

(2014) S. Labialle et al.   EMBO JOURNAL

Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at theKcnq1locus

(2014) He Zhang et al.   JOURNAL OF CELL BIOLOGY

Regulatory Interactions between RNA and Polycomb Repressive Complex 2

(2014) Catherine Cifuentes-Rojas et al.   MOLECULAR CELL

Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin

(2014) Syuzo Kaneko et al.   MOLECULAR CELL

The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome

(2014) Yonatan Stelzer et al.   NATURE GENETICS

Genomic Imprinting in Mammals

(2014) D. P. Barlow et al.   Cold Spring Harbor Perspectives in Biology

R-loop formation atSnord116mediates topotecan inhibition ofUbe3a-antisenseand allele-specific chromatin decondensation

(2013) Weston T. Powell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1

(2013) P. Monnier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Truncation of Ube3a-ATS Unsilences Paternal Ube3a and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model

(2013) Linyan Meng et al.   PLoS Genetics

Mechanisms of long range silencing by imprinted macro non-coding RNAs

(2012) Florian M Pauler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing

(2012) F. Mohammad et al.   DEVELOPMENT

Small regulatory RNAs controlled by genomic imprinting and their contribution to human disease

(2012) Michael Girardot et al.   Epigenetics

Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells

(2012) Feng Yang et al.   FEBS Journal

Genome-wide analysis of long noncoding RNA stability

(2012) M. B. Clark et al.   GENOME RESEARCH

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a

(2012) Linyan Meng et al.   HUMAN MOLECULAR GENETICS

Macro lncRNAs

(2012) Philipp M. Guenzl et al.   RNA Biology

Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing

(2012) P. A. Latos et al.   SCIENCE

Differentiation-Driven Nucleolar Association of the Mouse Imprinted Kcnq1 Locus

(2012) Andrew M. Fedoriw et al.   G3-Genes Genomes Genetics

The Kcnq1ot1 Long Non-Coding RNA Affects Chromatin Conformation and Expression of Kcnq1, but Does Not Regulate Its Imprinting in the Developing Heart

(2012) Lisa Korostowski et al.   PLoS Genetics

Modeling the asymmetric evolution of a mouse and rat-specific microRNA gene cluster intron 10 of the Sfmbt2 gene

(2011) Stefan Lehnert et al.   BMC GENOMICS

Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells

(2011) M. C. Golding et al.   DEVELOPMENT

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

An RNA-Seq Strategy to Detect the Complete Coding and Non-Coding Transcriptome Including Full-Length Imprinted Macro ncRNAs

(2011) Ru Huang et al.   PLoS One

MicroRNAs 296 and 298 are imprinted and part of the GNAS/Gnas cluster and miR-296 targets IKBKE and Tmed9

(2011) J. E. Robson et al.   RNA

Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster

(2011) Christine M. Williamson et al.   PLoS Genetics

Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1

(2010) F. Mohammad et al.   DEVELOPMENT

Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq

(2010) Jing Zhao et al.   MOLECULAR CELL

Regulation of imprinted expression by macro non-coding RNAs

(2010) Paulina A. Latos et al.   RNA Biology

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing

(2009) L. Redrup et al.   DEVELOPMENT

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice

(2009) A. Gabory et al.   DEVELOPMENT

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts

(2009) M.-L. Bortolin-Cavaille et al.   NUCLEIC ACIDS RESEARCH

At Least Ten Genes Define the Imprinted Dlk1-Dio3 Cluster on Mouse Chromosome 12qF1

(2009) John P. Hagan et al.   PLoS One

Structural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region

(2008) Martin Kircher et al.   BMC GENOMICS

Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

(2008) Rémi Terranova et al.   DEVELOPMENTAL CELL

Kcnq1ot1/Lit1 Noncoding RNA Mediates Transcriptional Silencing by Targeting to the Perinucleolar Region

(2008) F. Mohammad et al.   MOLECULAR AND CELLULAR BIOLOGY

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin

(2008) T. Nagano et al.   SCIENCE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE