Introns mediate post-transcriptional enhancement of nuclear gene expression in the green microalga Chlamydomonas reinhardtii

Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation

(2019) Razvan V Chereji et al.   GENOME RESEARCH

Organization and regulation of gene transcription

(2019) Patrick Cramer   NATURE

Intronserter, an advanced online tool for design of intron containing transgenes

(2019) Daniel Jaeger et al.   Algal Research-Biomass Biofuels and Bioproducts

An intron-derived motif strongly increases gene expression from transcribed sequences through a splicing independent mechanism in Arabidopsis thaliana

(2019) Jenna E. Gallegos et al.   Scientific Reports

Good News for Nuclear Transgene Expression in Chlamydomonas

(2019) Michael Schroda   Cells

SV40 intron, a potent strong intron element that effectively increases transgene expression in transfected Chinese hamster ovary cells

(2018) Dan-hua Xu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii

(2018) Kyle J. Lauersen et al.   METABOLIC ENGINEERING

Tailored carbon partitioning for phototrophic production of ( E )-α-bisabolene from the green microalga Chlamydomonas reinhardtii

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Intron-containing algal transgenes mediate efficient recombinant gene expression in the green microalga Chlamydomonas reinhardtii

(2018) Thomas Baier et al.   NUCLEIC ACIDS RESEARCH

Enhancing heterologous expression in Chlamydomonas reinhardtii by transcript sequence optimization

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Synthetic metabolic pathways for photobiological conversion of CO2 into hydrocarbon fuel

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Birth of a Photosynthetic Chassis: A MoClo Toolkit Enabling Synthetic Biology in the Microalga Chlamydomonas reinhardtii

(2018) Pierre Crozet et al.   ACS Synthetic Biology

Engineered Fusion Proteins for Efficient Protein Secretion and Purification of a Human Growth Factor from the Green Microalga Chlamydomonas reinhardtii

(2018) Thomas Baier et al.   ACS Synthetic Biology

How introns enhance gene expression

(2017) Orit Shaul   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Optimal artificial mini-introns for transgenic expression in the cells of mice and hamsters

(2017) M. V. Tikhonov et al.   MOLECULAR BIOLOGY

Alternative splicing as a regulator of development and tissue identity

(2017) Francisco E. Baralle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intron DNA Sequences Can Be More Important Than the Proximal Promoter in Determining the Site of Transcript Initiation

(2017) Jenna E. Gallegos et al.   PLANT CELL

Efficient phototrophic production of a high-value sesquiterpenoid from the eukaryotic microalga Chlamydomonas reinhardtii

(2016) Kyle J. Lauersen et al.   METABOLIC ENGINEERING

Intron sequences that stimulate gene expression in Arabidopsis

(2016) Alan B. Rose et al.   PLANT MOLECULAR BIOLOGY

UV-mediated Chlamydomonas mutants with enhanced nuclear transgene expression by disruption of DNA methylation-dependent and independent silencing systems

(2016) Sari Dewi Kurniasih et al.   PLANT MOLECULAR BIOLOGY

Perfect timing: splicing and transcription rates in living cells

(2016) Tara Alpert et al.   Wiley Interdisciplinary Reviews-RNA

Synthetic promoters capable of driving robust nuclear gene expression in the green alga Chlamydomonas reinhardtii

(2016) Melissa A. Scranton et al.   Algal Research-Biomass Biofuels and Bioproducts

Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer

(2016) Yiwen Fang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Targeted expression of nuclear transgenes in Chlamydomonas reinhardtii with a versatile, modular vector toolkit

(2015) Kyle J. Lauersen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Dissecting the contributions of GC content and codon usage to gene expression in the model algaChlamydomonas reinhardtii

(2015) Rouhollah Barahimipour et al.   PLANT JOURNAL

The enduring mystery of intron-mediated enhancement

(2015) Jenna E. Gallegos et al.   PLANT SCIENCE

Regulation of Transcription by Long Noncoding RNAs

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Nitrogen-Sparing Mechanisms in Chlamydomonas Affect the Transcriptome, the Proteome, and Photosynthetic Metabolism

(2014) S. Schmollinger et al.   PLANT CELL

Identification and validation of promoters and cis-acting regulatory elements

(2013) Carlos M. Hernandez-Garcia et al.   PLANT SCIENCE

Functional analysis of three type-2 DGAT homologue genes for triacylglycerol production in the green microalga Chlamydomonas reinhardtii

(2012) M. La Russa et al.   JOURNAL OF BIOTECHNOLOGY

Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries

(2012) Alessandro Vannini et al.   MOLECULAR CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Role for gene looping in intron-mediated enhancement of transcription

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The Function of Introns

(2012) Michal Chorev et al.   Frontiers in Genetics

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism

(2011) R. L. Chang et al.   Molecular Systems Biology

Comparative and functional analysis of intron-mediated enhancement signals reveals conserved features among plants

(2011) G. Parra et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis of alternative splicing in Chlamydomonas reinhardtii

(2010) Adam Labadorf et al.   BMC GENOMICS

Splicing-Dependent RNA Polymerase Pausing in Yeast

(2010) Ross D. Alexander et al.   MOLECULAR CELL

Strategies to facilitate transgene expression in Chlamydomonas reinhardtii

(2009) Alke Eichler-Stahlberg et al.   PLANTA

Nuclear architecture and gene regulation

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Widespread distribution of a unique marine protistan lineage

(2008) Marie L. Cuvelier et al.   ENVIRONMENTAL MICROBIOLOGY

A complex intronic enhancer regulates expression of theCFTRgene by direct interaction with the promoter

(2008) Christopher J. Ott et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Promoter-Proximal Introns in Arabidopsis thaliana Are Enriched in Dispersed Signals that Elevate Gene Expression

(2008) A. B. Rose et al.   PLANT CELL

Generation ofChlamydomonasstrains that efficiently express nuclear transgenes

(2008) Juliane Neupert et al.   PLANT JOURNAL

An Optimized, Chemically Regulated Gene Expression System for Chlamydomonas

(2008) Paola Ferrante et al.   PLoS One

Gene Regulation by Transcription Factors and MicroRNAs

(2008) O. Hobert   SCIENCE