In silico co-factor balance estimation using constraint-based modelling informs metabolic engineering in Escherichia coli

Metabolic flux responses to deletion of 20 core enzymes reveal flexibility and limits of E. coli metabolism

(2019) Christopher P. Long et al.   METABOLIC ENGINEERING

Systematic engineering of the central metabolism in Escherichia coli for effective production of n-butanol

(2016) Mukesh Saini et al.   Biotechnology for Biofuels

Assembly of F1F0-ATP synthases

(2015) Thilo Rühle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Method to Constrain Genome-Scale Models with 13C Labeling Data

(2015) Héctor García Martín et al.   PLoS Computational Biology

A synthetic O2-tolerant butanol pathway exploiting native fatty acid biosynthesis inEscherichia coli

(2014) András Pásztor et al.   BIOTECHNOLOGY AND BIOENGINEERING

Towards large scale fermentative production of succinic acid

(2014) Mickel LA Jansen et al.   CURRENT OPINION IN BIOTECHNOLOGY

An integrated biotechnology platform for developing sustainable chemical processes

(2014) Nelson R. Barton et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism

(2014) Elad Noor et al.   PLoS Computational Biology

Energy coupling in Saccharomyces cerevisiae: selected opportunities for metabolic engineering

(2012) Stefan Kok et al.   FEMS YEAST RESEARCH

Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli

(2012) Eugenio Meza et al.   Microbial Cell Factories

ATP drives direct photosynthetic production of 1-butanol in cyanobacteria

(2012) E. I. Lan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elimination of Thermodynamically Infeasible Loops in Steady-State Metabolic Models

(2011) Jan Schellenberger et al.   BIOPHYSICAL JOURNAL

Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals

(2011) Clementina Dellomonaco et al.   NATURE

Relative potential of biosynthetic pathways for biofuels and bio-based products

(2011) Deepak Dugar et al.   NATURE BIOTECHNOLOGY

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

(2011) Harry Yim et al.   Nature Chemical Biology

Microbial production of bulk chemicals: development of anaerobic processes

(2011) Ruud A. Weusthuis et al.   TRENDS IN BIOTECHNOLOGY

Metabolic and Transcriptional Response to Cofactor Perturbations in Escherichia coli

(2010) Anders K. Holm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergy between 13C-metabolic flux analysis and flux balance analysis for understanding metabolic adaption to anaerobiosis in E. coli

(2010) Xuewen Chen et al.   METABOLIC ENGINEERING

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Different Biochemical Mechanisms Ensure Network-Wide Balancing of Reducing Equivalents in Microbial Metabolism

(2009) T. Fuhrer et al.   JOURNAL OF BACTERIOLOGY