Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics

(2020) Simon Zenke et al.   IMMUNITY

A Targeted Multi-omic Analysis Approach Measures Protein Expression and Low-Abundance Transcripts on the Single-Cell Level

(2020) Florian Mair et al.   Cell Reports

Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells

(2019) Jan. P. Gerlach et al.   Scientific Reports

Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation

(2019) Ricardo J. Miragaia et al.   IMMUNITY

Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells

(2019) Eleni P. Mimitou et al.   NATURE METHODS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM

(2019) Huidong Chen et al.   Nature Communications

CTLA-4–mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

(2019) Vitalijs Ovcinnikovs et al.   Science Immunology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR

(2018) David Zemmour et al.   NATURE IMMUNOLOGY

Frequencies of circulating regulatory TIGIT+CD38+ effector T cells correlate with the course of inflammatory bowel disease

(2018) Maria E. Joosse et al.   Mucosal Immunology

IL-12, IL-23 and IL-17 in IBD: immunobiology and therapeutic targeting

(2018) Alexander R. Moschen et al.   Nature Reviews Gastroenterology & Hepatology

A Single-Cell Sequencing Guide for Immunologists

(2018) Peter See et al.   Frontiers in Immunology

CD80 Regulates Th17 Cell Differentiation in Coxsackie Virus B3-Induced Acute Myocarditis

(2017) Yanlan Huang et al.   INFLAMMATION

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity

(2017) Ricardo C. Ferreira et al.   JOURNAL OF AUTOIMMUNITY

Scaling single-cell genomics from phenomenology to mechanism

(2017) Amos Tanay et al.   NATURE

Multiplexed quantification of proteins and transcripts in single cells

(2017) Vanessa M Peterson et al.   NATURE BIOTECHNOLOGY

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput

(2017) Todd M Gierahn et al.   NATURE METHODS

Single-cell transcriptomics to explore the immune system in health and disease

(2017) Michael J. T. Stubbington et al.   SCIENCE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6

(2016) Dennis Stauss et al.   EMBO JOURNAL

Diffusion pseudotime robustly reconstructs lineage branching

(2016) Laleh Haghverdi et al.   NATURE METHODS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

CD28/CTLA-4/B7 costimulatory pathway blockade affects regulatory T-cell function in autoimmunity

(2015) Isabel Vogel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Oct1 and OCA-B are selectively required for CD4 memory T cell function

(2015) Arvind Shakya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Abatacept (CTLA-4Ig) treatment reduces T cell apoptosis and regulatory T cell suppression in patients with rheumatoid arthritis

(2015) Michael Bonelli et al.   RHEUMATOLOGY

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

CD86+ or HLA-G+ can be transferred via trogocytosis from myeloma cells to T cells and are associated with poor prognosis

(2012) R. Brown et al.   BLOOD

Trogocytosis of CD80 and CD86 by induced regulatory T cells

(2012) Peng Gu et al.   Cellular & Molecular Immunology

IL-2 Upregulates CD86 Expression on Human CD4+ and CD8+ T Cells

(2012) A. Paine et al.   JOURNAL OF IMMUNOLOGY

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

A New Vampire Saga: The Molecular Mechanism of T Cell Trogocytosis

(2011) Elaine Pashupati Dopfer et al.   IMMUNITY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Highly multiparametric analysis by mass cytometry

(2010) Olga Ornatsky et al.   JOURNAL OF IMMUNOLOGICAL METHODS