Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice
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Title
Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice
Authors
Keywords
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Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-07-16
DOI
10.1038/s41598-020-68616-9
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Related references
Note: Only part of the references are listed.- Genetics and pathophysiology of pancreatitis
- (2019) Julia Mayerle et al. GASTROENTEROLOGY
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- (2019) Zsanett Jancsó et al. GASTROENTEROLOGY
- Measuring digestive protease activation in the mouse pancreas
- (2019) Dóra Mosztbacher et al. PANCREATOLOGY
- Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice
- (2018) Zsanett Jancsó et al. GASTROENTEROLOGY
- A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation
- (2018) Andrea Geisz et al. Nature Communications
- Genome-wide association study identifies inversion in theCTRB1-CTRB2locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis
- (2017) Jonas Rosendahl et al. GUT
- Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes
- (2017) Eszter Boros et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chymotrypsinogen C Genetic Variants, Including c.180TT, Are Strongly Associated With Chronic Pancreatitis in Pediatric Patients
- (2017) Alicja Monika Grabarczyk et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2
- (2016) András Szabó et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis
- (2015) András Szabó et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population
- (2015) Jessica LaRusch et al. Clinical and Translational Gastroenterology
- Autoactivation of Mouse Trypsinogens Is Regulated by Chymotrypsin C via Cleavage of the Autolysis Loop
- (2013) Balázs Csaba Németh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen
- (2012) András Szabó et al. FEBS Journal
- Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk
- (2012) Sebastian Beer et al. GUT
- CFTR,SPINK1,CTRCandPRSS1variants in chronic pancreatitis: is the role of mutatedCFTRoverestimated?
- (2012) Jonas Rosendahl et al. GUT
- High Affinity Small Protein Inhibitors of Human Chymotrypsin C (CTRC) Selected by Phage Display Reveal Unusual Preference for P4′ Acidic Residues
- (2011) András Szabó et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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