Cyclic di-GMP cyclase SSFG_02181 from Streptomyces ghanaensis ATCC14672 regulates antibiotic biosynthesis and morphological differentiation in streptomycetes

Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes

(2020) Roman Makitrynskyy et al.   NUCLEIC ACIDS RESEARCH

Overexpression of the diguanylate cyclase CdgD blocks developmental transitions and antibiotic biosynthesis in Streptomyces coelicolor

(2019) Xiaocao Liu et al.   Science China-Life Sciences

c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces

(2019) Kelley A. Gallagher et al.   MOLECULAR CELL

Genomic Insights into Evolution of AdpA Family Master Regulators of Morphological Differentiation and Secondary Metabolism in Streptomyces

(2018) Mariia Rabyk et al.   JOURNAL OF MOLECULAR EVOLUTION

Expression Patterns, Genomic Conservation and Input Into Developmental Regulation of the GGDEF/EAL/HD-GYP Domain Proteins in Streptomyces

(2018) Mahmoud M. Al-Bassam et al.   Frontiers in Microbiology

C-di-GMP Synthesis: Structural Aspects of Evolution, Catalysis and Regulation

(2016) Tilman Schirmer   JOURNAL OF MOLECULAR BIOLOGY

Testing the utility of site-specific recombinases for manipulations of genome of moenomycin producer Streptomyces ghanaensis ATCC14672

(2015) M. Lopatniuk et al.   JOURNAL OF APPLIED GENETICS

Nucleotide Second Messenger-Mediated Regulation of a Muralytic Enzyme inStreptomyces

(2015) Renée J. St-Onge et al.   MOLECULAR MICROBIOLOGY

Unusual site-specific DNA integration into the highly active pseudo-attB of the Streptomyces albus J1074 genome

(2014) Bohdan Bilyk et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

(2014) Natalia Tschowri et al.   CELL

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

(2013) R. Makitrynskyy et al.   Open Biology

Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces, Revealed the Extent and Complexity of the AdpA Regulatory Network

(2012) A. Higo et al.   DNA RESEARCH

Cyclic Di-GMP Phosphodiesterases RmdA and RmdB Are Involved in Regulating Colony Morphology and Development in Streptomyces coelicolor

(2012) T. D. Hull et al.   JOURNAL OF BACTERIOLOGY

The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)2at the active site

(2011) Chao-Yu Yang et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

β-Glucuronidase as a Sensitive and Versatile Reporter in Actinomycetes

(2011) Maksym Myronovskyi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Streptomyces ghanaensis pleiotropic regulatory gene wblA gh influences morphogenesis and moenomycin production

(2011) Mariia Rabyk et al.   BIOTECHNOLOGY LETTERS

Identification and Characterization of CdgB, a Diguanylate Cyclase Involved in Developmental Processes in Streptomyces coelicolor

(2011) N. T. Tran et al.   JOURNAL OF BACTERIOLOGY

The actinobacteria-specific gene wblA controls major developmental transitions in Streptomyces coelicolor A3(2)

(2011) K. Fowler-Goldsworthy et al.   MICROBIOLOGY-SGM

Ligand-Binding PAS Domains in a Genomic, Cellular, and Structural Context

(2010) Jonathan T. Henry et al.   Annual Review of Microbiology

Important Roles of Tyr43 at the Putative Heme Distal Side in the Oxygen Recognition and Stability of the Fe(II)−O2Complex of YddV, a Globin-Coupled Heme-Based Oxygen Sensor Diguanylate Cyclase

(2010) Kenichi Kitanishi et al.   BIOCHEMISTRY

Genetic factors that influence moenomycin production in streptomycetes

(2010) Roman Makitrynskyy et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth

(2010) Chris D. Den Hengst et al.   MOLECULAR MICROBIOLOGY

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

(2010) Bohdan Ostash et al.   NATURAL PRODUCT REPORTS

Complete Characterization of the Seventeen Step Moenomycin Biosynthetic Pathway

(2009) Bohdan Ostash et al.   BIOCHEMISTRY

A Flavin Cofactor-Binding PAS Domain Regulates c-di-GMP Synthesis inAxDGC2 fromAcetobacter xylinum

(2009) Yaning Qi et al.   BIOCHEMISTRY

Catalytic Mechanism of Cyclic Di-GMP-Specific Phosphodiesterase: a Study of the EAL Domain-Containing RocR from Pseudomonas aeruginosa

(2008) F. Rao et al.   JOURNAL OF BACTERIOLOGY

Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium

(2008) Klas Flärdh et al.   NATURE REVIEWS MICROBIOLOGY