Overexpression of PGC-1α influences the mitochondrial unfolded protein response (mtUPR) induced by MPP+ in human SH-SY5Y neuroblastoma cells

Signaling and Regulation of the Mitochondrial Unfolded Protein Response

(2019) Nandhitha Uma Naresh et al.   Cold Spring Harbor Perspectives in Biology

Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity

(2019) Di Hu et al.   ACTA NEUROPATHOLOGICA

Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity

(2019) Yingqing Wang et al.   Aging-US

Selective Activation of Human Caseinolytic Protease P (ClpP)

(2018) Matthias Stahl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The different axes of the mammalian mitochondrial unfolded protein response

(2018) Christian Münch   BMC BIOLOGY

The mitochondrial unfolded protein response: Signaling from the powerhouse

(2017) Mohammed A. Qureshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Paraquat-and Rotenone-Induced Models of Parkinson's Disease

(2017) R. Nisticò et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

TRPM2 Promotes Neurotoxin MPP+/MPTP-Induced Cell Death

(2016) Yuyang Sun et al.   MOLECULAR NEUROBIOLOGY

Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress

(2016) T. Kelly Rainbolt et al.   Cell Reports

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

(2016) Bianca Hartmann et al.   eLife

The loss of LRPPRC function induces the mitochondrial unfolded protein response

(2015) Fabian Köhler et al.   Aging-US

An overview of pentatricopeptide repeat proteins and their applications

(2015) Sam Manna   BIOCHIMIE

Mitochondrial quality control pathways as determinants of metabolic health

(2015) Ntsiki M. Held et al.   BIOESSAYS

The mitochondrial unfolded protein response—synchronizing genomes

(2015) Virginija Jovaisaite et al.   CURRENT OPINION IN CELL BIOLOGY

Functional Significance of Point Mutations in Stress Chaperone Mortalin and Their Relevance to Parkinson Disease

(2015) Renu Wadhwa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Heat Shock Protein (Hsp) 70 and Hsp10 Cooperate in the Formation of Hsp60 Complexes

(2015) Lena Böttinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aerobic Exercise Recovers Disuse-induced Atrophy Through the Stimulus of the LRP130/PGC-1α Complex in Aged Rats

(2015) Ivan J. Vechetti-Junior et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Overexpression of PGC-1α Influences Mitochondrial Signal Transduction of Dopaminergic Neurons

(2015) Qinyong Ye et al.   MOLECULAR NEUROBIOLOGY

Proteostasis and aging

(2015) Susmita Kaushik et al.   NATURE MEDICINE

Mitochondrial Proteostasis in the Control of Aging and Longevity

(2014) Martin Borch Jensen et al.   Cell Metabolism

YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress

(2014) T. K. Rainbolt et al.   EMBO REPORTS

New insights into antioxidant strategies against paraquat toxicity

(2014) T. Blanco-Ayala et al.   FREE RADICAL RESEARCH

Adenovirus: The First Effective In Vivo Gene Delivery Vector

(2014) Ronald G. Crystal   HUMAN GENE THERAPY

Protective Effects of Salidroside in the MPTP/MPP+-Induced Model of Parkinson's Disease through ROS–NO-Related Mitochondrion Pathway

(2014) Songhai Wang et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1

(2014) L F Burbulla et al.   Cell Death & Disease

PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis

(2014) S Baldelli et al.   Cell Death & Disease

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys

(2013) Ariadna Recasens et al.   ANNALS OF NEUROLOGY

The cerebellum in Parkinson’s disease

(2013) Tao Wu et al.   BRAIN

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

Regulation of mitochondrial biogenesis and PGC-1α under cellular stress

(2013) Tina Wenz   MITOCHONDRION

Pharmacological approaches to restore mitochondrial function

(2013) Pénélope A. Andreux et al.   NATURE REVIEWS DRUG DISCOVERY

Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond

(2013) Cole M. Haynes et al.   TRENDS IN CELL BIOLOGY

Effects of Resveratrol and SIRT1 on PGC-1α Activity and Mitochondrial Biogenesis: A Reevaluation

(2013) Kazuhiko Higashida et al.   PLOS BIOLOGY

Surveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein Response

(2013) Eva D. Runkel et al.   PLoS Genetics

Role of Oxidative Stress in Parkinson's Disease

(2013) Onyou Hwang   Experimental Neurobiology

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

(2011) Benedetta Ruzzenente et al.   EMBO JOURNAL

Rotenone, Paraquat, and Parkinson’s Disease

(2011) Caroline M. Tanner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson’s disease model

(2011) Won-Seok Choi et al.   JOURNAL OF CELL BIOLOGY

PPR proteins network as site-specific RNA editing factors in plant organelles

(2011) Anja Zehrmann et al.   RNA Biology

Mitochondrial protein quality control during biogenesis and aging

(2011) Brooke M. Baker et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

(2010) Lena F. Burbulla et al.   HUMAN MOLECULAR GENETICS

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That Regulates Posttranscriptional Gene Expression in Mitochondria

(2010) Florin Sasarman et al.   MOLECULAR BIOLOGY OF THE CELL

Quality control of mitochondria: protection against neurodegeneration and ageing

(2008) Takashi Tatsuta et al.   EMBO JOURNAL

Adenovirus vector induced innate immune responses: Impact upon efficacy and toxicity in gene therapy and vaccine applications

(2007) Zachary C. Hartman et al.   VIRUS RESEARCH