The Effectiveness of Probiotics in the Treatment of Inflammatory Bowel Disease (IBD)—A Critical Review

Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses

(2020) Jiří Hrdý et al.   Scientific Reports

A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function

(2019) Jie Gao et al.   Frontiers in Microbiology

Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn’s Disease

(2019) Williams Turpin et al.   INFLAMMATORY BOWEL DISEASES

Epidemiology and Clinical Outcomes of Inflammatory Bowel Disease: A Hospital-Based Study in Central Taiwan

(2019) Jen-Wei Chou et al.   Gastroenterology Research and Practice

Lactobacillus rhamnosus GG components, SLP, gDNA and CpG, exert protective effects on mouse macrophages upon lipopolysaccharide challenge

(2019) S.R. Qi et al.   LETTERS IN APPLIED MICROBIOLOGY

Differences in the intestinal microbiome of healthy children and patients with newly diagnosed Crohn’s disease

(2019) Kinga Kowalska-Duplaga et al.   Scientific Reports

Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines

(2018) Mingming Yin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Efficacy of Bifidobacterium breve Fermented Milk in Maintaining Remission of Ulcerative Colitis

(2018) Katsuyoshi Matsuoka et al.   DIGESTIVE DISEASES AND SCIENCES

Probiotic Cell-Free Supernatants Exhibited Anti-Inflammatory and Antioxidant Activity on Human Gut Epithelial Cells and Macrophages Stimulated with LPS

(2018) Stefania De Marco et al.   Evidence-based Complementary and Alternative Medicine

Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs

(2018) Yingdi Zhang et al.   MEDIATORS OF INFLAMMATION

The effects of probiotics on total cholesterol

(2018) Lang Wang et al.   MEDICINE

Increased fecal calprotectin levels in Crohn’s disease correlate with elevated serum Th1- and Th17-associated cytokines

(2018) Arno R. Bourgonje et al.   PLoS One

VSL#3 can prevent ulcerative colitis-associated carcinogenesis in mice

(2018) Chun-Sai-Er Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Immunomodulatory Effects of Probiotics on Cytokine Profiles

(2018) Md. Abul Kalam Azad et al.   Biomed Research International

The Epithelial Barrier Model Shows That the Properties of VSL#3 Depend from Where It Is Manufactured

(2018) Paola Palumbo et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

No association of alcohol use and the risk of ulcerative colitis or Crohn’s disease: data from a European Prospective cohort study (EPIC)

(2017) M M Bergmann et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Cutaneous Morbidity Among Inflammatory Bowel Disease Patients: A Cohort Study

(2017) Júlia Vide et al.   Journal of Crohns & Colitis

Immunomodulatory effects of Bifidobacterium bifidum 231 on trinitrobenzenesulfonic acid-induced ulcerative colitis in rats

(2017) C S V Satish Kumar et al.   RESEARCH IN VETERINARY SCIENCE

The Probiotic Compound VSL#3 Modulates Mucosal, Peripheral, and Systemic Immunity Following Murine Broad-Spectrum Antibiotic Treatment

(2017) Ira Ekmekciu et al.   Frontiers in Cellular and Infection Microbiology

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity

(2017) Michele Biagioli et al.   Frontiers in Pharmacology

Identification of proteins involved in the anti-inflammatory properties of Propionibacterium freudenreichii by means of a multi-strain study

(2017) Stéphanie-Marie Deutsch et al.   Scientific Reports

Duration of Inflammatory Bowel Disease Is Associated With Increased Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis and IBD

(2016) Aliya F Gulamhusein et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Oral Administration of Probiotics Inhibits Absorption of the Heavy Metal Cadmium by Protecting the Intestinal Barrier

(2016) Qixiao Zhai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Design and validation of an orally administrated active L. fermentum-L. acidophilus probiotic formulation using colorectal cancer Apc Min/+ mouse model

(2016) Imen Kahouli et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The long-term effects of probiotics in the therapy of ulcerative colitis: A clinical study

(2016) Vincenzo Davide Palumbo et al.   BIOMEDICAL PAPERS-OLOMOUC

Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe

(2016) Antoine Racine et al.   INFLAMMATORY BOWEL DISEASES

Profiles of Lamina Propria T Helper Cell Subsets Discriminate Between Ulcerative Colitis and Crohnʼs Disease

(2016) Ji Li et al.   INFLAMMATORY BOWEL DISEASES

Influence of food and lifestyle on the risk of developing inflammatory bowel disease

(2016) O. Niewiadomski et al.   INTERNAL MEDICINE JOURNAL

Helminth infection promotes colonization resistance via type 2 immunity

(2016) Deepshika Ramanan et al.   SCIENCE

Extraintestinal manifestations of inflammatory bowel disease: Do they influence treatment and outcome?

(2016) Fernando Tavarela Veloso   WORLD JOURNAL OF GASTROENTEROLOGY

The Probiotic VSL#3 Has Anti-inflammatory Effects and Could Reduce Endoscopic Recurrence After Surgery for Crohn's Disease

(2015) Richard N. Fedorak et al.   Clinical Gastroenterology and Hepatology

Efficacy of probiotic treatment withBifidobacterium longum 536for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial

(2015) Hiroyuki Tamaki et al.   Digestive Endoscopy

Breakthrough Lactobacillus rhamnosus GG bacteremia associated with probiotic use in an adult patient with severe active ulcerative colitis: case report and review of the literature

(2015) Simone Meini et al.   INFECTION

High School Diet and Risk of Crohnʼs Disease and Ulcerative Colitis

(2015) Ashwin N. Ananthakrishnan et al.   INFLAMMATORY BOWEL DISEASES

Determinants of Intestinal Permeability in Healthy First-Degree Relatives of Individuals with Crohnʼs Disease

(2015) David Kevans et al.   INFLAMMATORY BOWEL DISEASES

Emerging leadership lecture: Inflammatory bowel disease in Asia: Emergence of a “Western” disease

(2015) Siew C Ng   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

(2015) Jimmy Z Liu et al.   NATURE GENETICS

A Four-Probiotics Regimen Reduces Postoperative Complications After Colorectal Surgery: A Randomized, Double-Blind, Placebo-Controlled Study

(2015) Katerina Kotzampassi et al.   WORLD JOURNAL OF SURGERY

Bifidobacterium longumsubsp.infantisBB-02 attenuates acute murine experimental model of inflammatory bowel disease

(2015) S.D.A. Elian et al.   Beneficial Microbes

2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 signaling

(2015) Emilien Loeuillard   WORLD JOURNAL OF GASTROENTEROLOGY

IBD Candidate Genes and Intestinal Barrier Regulation

(2014) Declan F. McCole   INFLAMMATORY BOWEL DISEASES

Extraintestinal manifestations in Crohn’s disease and ulcerative colitis: results from a prospective, population-based European inception cohort

(2014) Rune Isene et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Pulmonary manifestations of inflammatory bowel disease

(2014) Xiao-Qing Ji   WORLD JOURNAL OF GASTROENTEROLOGY

Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease

(2013) Ashwin N Ananthakrishnan et al.   GUT

A tale of two diseases: The history of inflammatory bowel disease

(2013) Daniel J. Mulder et al.   Journal of Crohns & Colitis

Faecalibacterium prausnitzii supernatant improves intestinal barrier function in mice DSS colitis

(2013) Anders H Carlsson et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

VSL#3 probiotic modifies mucosal microbial composition but does not reduce colitis-associated colorectal cancer

(2013) Janelle C. Arthur et al.   Scientific Reports

Excess primary intestinal lymphoproliferative disorders in patients with inflammatory bowel disease

(2012) Harry Sokol et al.   INFLAMMATORY BOWEL DISEASES

Translatability of helminth therapy in inflammatory bowel diseases

(2012) Joel V. Weinstock et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria

(2012) Josep Bassaganya-Riera et al.   PLoS One

Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer

(2011) Caroline B. Appleyard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Beneficial Effects of Probiotic Bifidobacterium and Galacto-Oligosaccharide in Patients with Ulcerative Colitis: A Randomized Controlled Study

(2011) Hideki Ishikawa et al.   DIGESTION

Anti-inflammatory properties of dairy lactobacilli

(2011) Clarissa Santos Rocha et al.   INFLAMMATORY BOWEL DISEASES

A randomised double-blind placebo-controlled trial with Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp. lactis BB-12 for maintenance of remission in ulcerative colitis

(2011) Signe Wildt et al.   Journal of Crohns & Colitis

Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment

(2011) Zuzana Zakostelska et al.   PLoS One

The Inflammatory Bowel Diseases and Ambient Air Pollution: A Novel Association

(2010) Gilaad G Kaplan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Treatment of Relapsing Mild-to-Moderate Ulcerative Colitis With the Probiotic VSL#3 as Adjunctive to a Standard Pharmaceutical Treatment: A Double-Blind, Randomized, Placebo-Controlled Study

(2010) Antonio Tursi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Alteration of the murine gut microbiota during infection with the parasitic helminth Heligmosomoides polygyrus

(2010) Seth T. Walk et al.   INFLAMMATORY BOWEL DISEASES

Bifidobacterium lactis inhibits NF-κB in intestinal epithelial cells and prevents acute colitis and colitis-associated colon cancer in mice

(2010) Seung Won Kim et al.   INFLAMMATORY BOWEL DISEASES

Ambient air pollution correlates with hospitalizations for inflammatory bowel disease

(2010) Ashwin N. Ananthakrishnan et al.   INFLAMMATORY BOWEL DISEASES

Pediatric modification of the Montreal classification for inflammatory bowel disease

(2010) Arie Levine et al.   INFLAMMATORY BOWEL DISEASES

Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes

(2010) P. Veiga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Pre-illness changes in dietary habits and diet as a risk factor for inflammatory bowel disease: A case-control study

(2010) Giovanni Maconi   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of probiotics on pro-inflammatory cytokines and NF-κB activation in ulcerative colitis

(2010) Sahar K Hegazy   WORLD JOURNAL OF GASTROENTEROLOGY

The Probiotic Preparation, VSL#3 Induces Remission in Patients With Mild-to-Moderately Active Ulcerative Colitis

(2009) Ajit Sood et al.   Clinical Gastroenterology and Hepatology

The tight junction in inflammatory disease: communication breakdown

(2009) Karen L Edelblum et al.   CURRENT OPINION IN PHARMACOLOGY

Clinical Outcomes of Patients with Ulcerative Colitis and Co-existing Clostridium difficile Infection

(2009) Daniela Jodorkovsky et al.   DIGESTIVE DISEASES AND SCIENCES

Butyrate utilization by the colonic mucosa in inflammatory bowel diseases

(2009) Ronan Thibault et al.   INFLAMMATORY BOWEL DISEASES

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

(2009) Nicola Eastaff-Leung et al.   JOURNAL OF CLINICAL IMMUNOLOGY

OCTN1 variant L503F is associated with familial and sporadic inflammatory bowel disease

(2009) Zhenwu Lin et al.   Journal of Crohns & Colitis

The Risk of Oral Contraceptives in the Etiology of Inflammatory Bowel Disease: A Meta-Analysis

(2008) J.A. Cornish et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

(2008) T Kobayashi et al.   GUT

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS

Helminths and the IBD hygiene hypothesis

(2008) Joel V. Weinstock et al.   INFLAMMATORY BOWEL DISEASES

Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis

(2008) Philip Alex et al.   INFLAMMATORY BOWEL DISEASES

Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: A pilot study

(2008) Hien Q. Huynh et al.   INFLAMMATORY BOWEL DISEASES

Regulation of inflammatory responses by IL-17F

(2008) Xuexian O. Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence ofSaccharomyces boulardiion the intestinal permeability of patients with Crohn's disease in remission

(2008) Eduardo Garcia Vilela et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY