Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

Sex differences in neurodevelopmental disorders

(2019) Tamara May et al.   CURRENT OPINION IN NEUROLOGY

Prenatal Nutritional Intervention Reduces Autistic-Like Behavior Rates Among Mthfr-Deficient Mice

(2019) Ayelet Orenbuch et al.   Frontiers in Neuroscience

Early nutrition influences developmental myelination and cognition in infants and young children

(2018) Sean Deoni et al.   NEUROIMAGE

Maternal oversupplementation with folic acid and its impact on neurodevelopment of offspring

(2018) Lauren K Murray et al.   NUTRITION REVIEWS

Methylenetetrahydrofolate reductase and psychiatric diseases

(2018) Lin Wan et al.   Translational Psychiatry

The Importance of Maternal Folate Status for Brain Development and Function of Offspring

(2018) Eva F G Naninck et al.   Advances in Nutrition

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring

(2017) Renata H. Bahous et al.   HUMAN MOLECULAR GENETICS

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Maternal Multivitamin Intake, Plasma Folate and Vitamin B12 Levels and Autism Spectrum Disorder Risk in Offspring

(2017) Ramkripa Raghavan et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Developmental Outcomes at 24 Months of Age in Toddlers Supplemented with Arachidonic Acid and Docosahexaenoic Acid: Results of a Double Blind Randomized, Controlled Trial

(2017) Angela Devlin et al.   Nutrients

Association of White Matter Structure With Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder

(2017) Yuta Aoki et al.   JAMA Psychiatry

High-dose maternal folic acid supplementation before conception impairs reversal learning in offspring mice

(2017) Kristin S. Henzel et al.   Scientific Reports

Low and high dietary folic acid levels perturb postnatal cerebellar morphology in growing rats

(2016) Teresa Partearroyo et al.   BRITISH JOURNAL OF NUTRITION

Prenatal folate, homocysteine and vitamin B12 levels and child brain volumes, cognitive development and psychological functioning: the Generation R Study

(2016) Charlotte L. Ars et al.   BRITISH JOURNAL OF NUTRITION

Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis

(2016) Ariel B. Ganz et al.   FASEB JOURNAL

Genome-wide changes in lncRNA, splicing and regional gene expression patterns in autism

(2016) Neelroop N. Parikshak et al.   NATURE

DNA Methylation Profiling at Single-Base Resolution Reveals Gestational Folic Acid Supplementation Influences the Epigenome of Mouse Offspring Cerebellum

(2016) Subit Barua et al.   Frontiers in Neuroscience

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

(2015) Karen E Christensen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

High concentrations of folate and unmetabolized folic acid in a cohort of pregnant Canadian women and umbilical cord blood

(2015) Lesley Plumptre et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

High Gestational Folic Acid Supplementation Alters Expression of Imprinted and Candidate Autism Susceptibility Genes in a sex-Specific Manner in Mouse Offspring

(2015) Subit Barua et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring

(2015) N.M. Jadavji et al.   NEUROSCIENCE

Increasing Maternal or Post-Weaning Folic Acid Alters Gene Expression and Moderately Changes Behavior in the Offspring

(2014) Subit Barua et al.   PLoS One

Folic Acid Supplements During Pregnancy and Child Psychomotor Development After the First Year of Life

(2014) Desirée Valera-Gran et al.   JAMA Pediatrics

Prenatal omega 3 fatty acid supplementation to a micronutrient imbalanced diet protects brain neurotrophins in both the cortex and hippocampus in the adult rat offspring

(2013) Pratiksha S. Sable et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Maternal micronutrients and brain global methylation patterns in the offspring

(2013) Pratiksha Sable et al.   NUTRITIONAL NEUROSCIENCE

Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans

(2012) Jian Yan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations

(2012) Louis J. Sparvero et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus

(2012) Nafisa M. Jadavji et al.   MOLECULAR GENETICS AND METABOLISM

Distribution of lipids in human brain

(2011) Antonio Veloso et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Maternal micronutrients (folic acid and vitamin B12) and omega 3 fatty acids: Implications for neurodevelopmental risk in the rat offspring

(2011) Suchitra Roy et al.   BRAIN & DEVELOPMENT

Nutritional Deficiencies and Phospholipid Metabolism

(2011) María S. Gimenez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modeling Autistic Features in Animals

(2011) PAUL H. PATTERSON   PEDIATRIC RESEARCH

Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

(2010) Karen E. Christensen et al.   JOURNAL OF NUTRITION

Acetylcholine in the cerebral cortex: Effects and clinical implications

(2010) E. E. Benarroch   NEUROLOGY

A bilateral cervical contusion injury model in mice: Assessment of gripping strength as a measure of forelimb motor function

(2009) Roberto M. Aguilar et al.   EXPERIMENTAL NEUROLOGY

The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake

(2009) S. W. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cognitive Impairment in Folate-Deficient Rats Corresponds to Depleted Brain Phosphatidylcholine and Is Prevented by Dietary Methionine without Lowering Plasma Homocysteine

(2008) Aron M. Troen et al.   JOURNAL OF NUTRITION

Spectroscopic findings in attention-deficit/hyperactivity disorder: Review and meta-analysis

(2008) Evgeniy Perlov et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR