The Adenovirus Dodecahedron: Beyond the Platonic Story

Viruses go modular

(2020) Ariel Shepley-McTaggart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialic Acid-Containing Glycans as Cellular Receptors for Ocular Human Adenoviruses: Implications for Tropism and Treatment

(2019) Naresh Chandra et al.   Viruses-Basel

Human adenovirus type 26 uses sialic acid–bearing glycans as a primary cell entry receptor

(2019) Alexander T. Baker et al.   Science Advances

Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display

(2019) Charles Vragniau et al.   Science Advances

HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo

(2019) Felix Alonso-Valenteen et al.   NUCLEIC ACIDS RESEARCH

Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells

(2018) Anandi Rajan et al.   Scientific Reports

Viral escape from endosomes and host detection at a glance

(2018) Jacqueline Staring et al.   JOURNAL OF CELL SCIENCE

Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy

(2017) Charles Vragniau et al.   JOURNAL OF VIROLOGY

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

(2015) Masaru Kanekiyo et al.   CELL

Connections matter - how viruses use cell-cell adhesion components

(2015) M. Mateo et al.   JOURNAL OF CELL SCIENCE

Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1

(2015) Hongjie Wang et al.   JOURNAL OF VIROLOGY

Preclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin

(2015) Maximilian Richter et al.   Molecular Therapy-Methods & Clinical Development

Adenovirus Infections in Immunocompetent and Immunocompromised Patients

(2014) T. Lion   CLINICAL MICROBIOLOGY REVIEWS

Towards a novel influenza vaccine: engineering of hemagglutinin on a platform of adenovirus dodecahedron

(2013) Antonina Naskalska et al.   BMC BIOTECHNOLOGY

Structural and Functional Studies on the Interaction of Adenovirus Fiber Knobs and Desmoglein 2

(2013) H. Wang et al.   JOURNAL OF VIROLOGY

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

(2013) Masaru Kanekiyo et al.   NATURE

An Intrinsically Disordered Region of the Adenovirus Capsid Is Implicated in Neutralization by Human Alpha Defensin 5

(2013) Justin W. Flatt et al.   PLoS One

Penton-Dodecahedral Particles Trigger Opening of Intercellular Junctions and Facilitate Viral Spread during Adenovirus Serotype 3 Infection of Epithelial Cells

(2013) Zhuo-Zhuang Lu et al.   PLoS Pathogens

Impact of Human Adenovirus Type 3 Dodecahedron on Host Cells and Its Potential Role in Viral Infection

(2012) P. Fender et al.   JOURNAL OF VIROLOGY

Construction and Characterization of Virus-Like Particles: A Review

(2012) Andris Zeltins   MOLECULAR BIOTECHNOLOGY

The Structural Basis for the Integrity of Adenovirus Ad3 Dodecahedron

(2012) Ewa Szolajska et al.   PLoS One

Functional Characterisation of the WW Minimal Domain for Delivering Therapeutic Proteins by Adenovirus Dodecahedron

(2012) Ana Villegas-Méndez et al.   PLoS One

Epithelial Junction Opener JO-1 Improves Monoclonal Antibody Therapy of Cancer

(2011) I. Beyer et al.   CANCER RESEARCH

Generation and Biological Properties of a Recombinant Dodecahedron Containing the Short Fiber Protein of the Human Adenovirus 41

(2011) Joselma Siqueira-Silva et al.   INTERVIROLOGY

The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding

(2010) E. Gout et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

In Vivo Delivery of Antigens by Adenovirus Dodecahedron Induces Cellular and Humoral Immune Responses to Elicit Antitumor Immunity

(2010) Ana Villegas-Mendez et al.   MOLECULAR THERAPY

Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14

(2010) Hongjie Wang et al.   NATURE MEDICINE

The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis

(2010) Emma C Nilsson et al.   NATURE MEDICINE

Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

(2010) Jason G. Smith et al.   PLoS Pathogens

Receptor usage of a newly emergent adenovirus type 14

(2009) Hongjie Wang et al.   VIROLOGY

Twisted epithelial–mesenchymal transition blocks senescence

(2008) Robert A. Weinberg   NATURE CELL BIOLOGY