Article
Chemistry, Applied
Danning Fu, Ruibin Wang, Yang Wang, Qianyu Sun, Chen Cheng, Xiaohui Guo, Rendang Yang
Summary: In this study, a rational strategy was used to design a silver nanowires-dual-cellulose conductive paper. The conductive paper showed good mechanical properties, electrical properties, and adhesion stability. It was demonstrated to be suitable for versatile flexible pressure sensors with fast response and high sensitivity to finger motion, voice recognition, and human pulse.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Analytical
Menbere Leul Mekonnen, Yitayal Admassu Workie, Wei-Nien Su, Bing Joe Hwang
Summary: This review discusses the fabrication of low-cost, flexible SERS substrates using paper, highlighting its advantages and methods. It evaluates the pros and cons of different fabrication methods, and explores ways to improve substrate performance and obtain additional analytical functionalities. Finally, it also suggests opportunities and challenges in realizing a low-cost commercial plasmonic paper substrate.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Richard Frimpong, Wongi Jang, Jun-Hyun Kim, Jeremy D. Driskell
Summary: The study presents a SERS-based immunoassay for point-of-care diagnostics, utilizing gold nanoparticle-modified filter paper as a capture membrane to achieve rapid and accurate biomarker detection. The technique offers advantages of low cost and short assay time, demonstrating potential for practical application in point-of-need testing.
Article
Chemistry, Multidisciplinary
Lei Yao, Qi Hao, Mingze Li, Xingce Fan, Guoqun Li, Xiao Tang, Yunjia Wei, Jiawei Wang, Teng Qiu
Summary: We propose and demonstrate sandwich plasmonic nanocavities as a surface-selection ruler to illustrate molecular orientations using surface-enhanced Raman spectroscopy. The field vector in the nanocavity presents a transverse spinning feature under specific excitations, allowing the selective amplification of Raman modes of target molecules. This method can be extended as a universal ruler for the identification of molecular orientations.
Article
Instruments & Instrumentation
Cyril Soliman, Jonathan Faircloth, Dandan Tu, Samuel Mabbott, Kristen Maitland, Gerard Cote
Summary: This study tested and compared the performance of eight commercial Raman spectrometers in point-of-care applications. The spectrometers with 780 and 785 nm laser sources showed reduced background signal and higher sensitivity. The spectrometer with single acquisition line readout functionality exhibited improved performance and faster, easier measurements. Portable handheld spectrometers demonstrated similar detection sensitivity to laboratory-grade instruments. Overall, portable Raman spectrometers have the potential to be used in POC settings with accuracy comparable to laboratory-grade instruments, low cost, fast signal readout, ease of use, and accessibility for underserved communities.
APPLIED SPECTROSCOPY
(2023)
Article
Materials Science, Multidisciplinary
Rahul Prajesh, Rakesh Kumar Saini, Ashok Kumar Sharma, Ajay Agarwal
Summary: Thiram is a fungicide with health-related issues when consumed regularly. Monitoring its presence in food and vegetables is crucial. This study aims to develop a low-cost and simple label-free SERS active substrate for detecting low-level concentrations of Thiram.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Analytical
Li Xiao, Shaolong Feng, Marti Z. Hua, Xiaonan Lu
Summary: A flexible nanocomposite composed of bacterial cellulose (BC) and gold nanoparticles (AuNPs) was developed as a SERS substrate for the sensitive and rapid detection of thiram residues on apple surface. The SERS substrate showed a high enhancement factor and a good linear correlation, with a detection limit satisfying regulatory requirements. This BC-based SERS substrate demonstrated excellent analytical performance and is suitable for the quantitative analysis of pesticides on food surfaces.
Article
Biochemical Research Methods
Ariadna B. Nowicka, Marta Czaplicka, Tomasz Szymborski, Agnieszka Kaminska
Summary: Surface-enhanced Raman spectroscopy (SERS) has been successfully used in analytical chemistry, molecular biology, and medical diagnostics. By combining the negative dielectrophoretic (nDEP) phenomenon and a flexible SERS platform, this study demonstrates quick isolation, concentration, and label-free identification of bacteria. The platform provides a strong enhancement factor, stability, and reproducibility for the SERS response. Introducing radial dielectrophoretic forces allows for efficient bacterial cell separation, concentration, and deposition onto the SERS-active surface, enabling vibration-based detection with the hybrid DEP-SERS device. The DEP-SERS system shows potential for rapid, cultivation-free, direct detection of bacteria in samples like urine and apple juice, offering new opportunities for pathogen detection.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Yuri Kang, Hyeok Jung Kim, Sung Hoon Lee, Hyeran Noh
Summary: Paper is a popular platform material in sensor research, with porosity, large surface area, and biodegradability. A silver-chitosan nanocomposite layer was successfully fabricated on paper celluloses using a layer-by-layer method and pH-triggered chitosan assembly, achieving evenly anchored silver nanoparticles and a detection limit of 5.13 ppb for 4-aminothiophenol in SERS measurement. The material shows potential for further biosensing applications.
Article
Nanoscience & Nanotechnology
Jayakumar Perumal, Hann Qian Lim, Amalina Binte Ebrahim Attia, Riazul Raziq, David Ian Leavesley, Zee Upton, U. S. Dinish, Malini Olivo
Summary: A biofunctionalized, cost-effective SERS substrate was developed for wound marker sensing, allowing for monitoring and detection of changes in proteins such as MMP-9 and TNF-alpha during wound healing. The platform demonstrated high sensitivity and selectivity, providing potential for a non-invasive, real-time measure of cutaneous wound healing.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Chemistry, Applied
Xiumei Zhang, Jingru Yao, Xiangnan Gong, Jianfeng Sun, Runhui Wang, Li Wang, Liyu Liu, Yingzhou Huang
Summary: In this study, a glass fibre paper with Ag nanoparticles was used for electrodynamic enrichment, combined with paper electrophoresis and field amplification sample stacking, to achieve convenient and sensitive detection of Raman and surface-enhanced Raman spectroscopy (SERS). The method showed significant improvement in detection limit and could detect trace organic contaminants in aquaculture and food applications.
Review
Chemistry, Multidisciplinary
Steven Quarin, Pietro Strobbia
Summary: Accurate diagnosis is crucial in many pathologies, prompting efforts to move diagnostic methods from specialized labs to point-of-care settings. Surface-enhanced Raman scattering (SERS) sensing offers advantages like simultaneous detection of multiple biotargets and increased accuracy, making it a promising method for point-of-care testing applications. Many groups are working towards translating SERS sensing methods from lab to the point of need.
FRONTIERS IN CHEMISTRY
(2021)
Review
Materials Science, Multidisciplinary
Mariadel Mar Gonzalez del Campo, Andreu Vaquer, Roberto de la Rica
Summary: In recent years, paper has become a widely used material for developing various types of sensors, and a polymer-based toolbox has emerged to enhance the functionalities of these devices. This article compiles examples from recent literature on microfluidic systems and polymer-based transducers implemented in paper-based analytical platforms. The use of printing methods to pattern polymers allows for mass production of these advanced paper-based devices without requiring specialized facilities.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Chemistry, Analytical
Mohammed L. Bouhoun, Pascal Blondeau, Yamina Louafi, Francisco J. Andrade
Summary: A novel paper-based potentiometric platform for monitoring water hardness is presented. The platform includes ion-selective electrodes for calcium and magnesium printed on paper, as well as a solid-state reference electrode. Results show good ability to predict hardness and decentralized measurements can be performed in just under two minutes, making this method suitable for domestic and industrial settings due to its simplicity and cost-effectiveness.
Article
Chemistry, Physical
Rosanna Pagano, Michela Ottolini, Ludovico Valli, Simona Bettini, Gabriele Giancane
Summary: A simple and cheap filter paper-based SERS substrate was developed for the sensing of tetracycline traces. The synthesized Ag nanodisks were used to decorate the filter paper surface for fast and easy analysis of aqueous solutions containing methylene blue and tetracycline. The results showed that the SERS substrate obtained with the proposed fabrication process can be implemented for low concentration tetracycline samples.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Review
Instruments & Instrumentation
Chia-Chi Huang
APPLIED SPECTROSCOPY REVIEWS
(2016)
Article
Biochemical Research Methods
Chih-Wei Hsu, Chia-Chi Huang, Jeng-Horng Sheu, Chia-Wen Lin, Lien-Fu Lin, Jong-Shiaw Jin, Wenlung Chen
JOURNAL OF BIOMEDICAL OPTICS
(2016)
Review
Neurosciences
Chia-Chi Huang, Ciro Isidoro
JOURNAL OF ALZHEIMERS DISEASE
(2017)
Article
Biochemical Research Methods
Chih-Hsien Wang, Chia-Chi Huang, Wenlung Chen
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2017)
Article
Spectroscopy
Cheng-Liang Huang, Chia-Chi Huang, Wenlung Chen
JOURNAL OF RAMAN SPECTROSCOPY
(2018)
Review
Instruments & Instrumentation
Chia-Chi Huang, Wenlung Chen
APPLIED SPECTROSCOPY REVIEWS
(2018)
Article
Chemistry, Analytical
Chia-Chi Huang, Wenlung Chen
Review
Food Science & Technology
Chia-Chi Huang, Yi-Shan Hung, Yih-Ming Weng, Wenlung Chen, Yen-Shi Lai
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2019)
Article
Food Science & Technology
Chia-Chi Huang, Zi-Han Hsu, Yen-Shi Lai
Summary: Food-mediated transmission of viral pathogens is a concern in food safety and public health. Raman spectroscopy provides valuable information for detecting viruses, with advancements in sensitivity and techniques like confocal Raman, surface-enhanced Raman scattering, and coherent anti-Stokes Raman scattering. The method allows rapid and minimal sample preparation for point-of-care testing, but challenges remain in its further development for food safety testing.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Zi-Han Hsu, Li Hsu, Chia-Chi Huang
Summary: This report introduces a method for preparing polyacrylamide materials with unique surface morphology. By cross-linking and reduction reactions, the smooth polymer surface is transformed into submicron cubic clusters impregnated with silver nanoparticles. The resulting material resembles the Great Barrier Reefs in overall morphology and features a high content of active silver nanostructures. It demonstrates versatility in surface-enhanced Raman scattering and methanolysis catalysis. These methods enlarge the surface area of the shape-adapting polymer material while generating minimal chemical waste.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Applied
Yu-San Chien, Chia-Wen Chang, Chia-Chi Huang
Summary: We report the fabrication of a SERS sensor using alumina beads as the solid support and demonstrate its high sensitivity with the model analyte 4-APDS. The key to sensitivity is a hydrophilic-hydrophobic surface gradient constructed by sequentially coating with surfactant and fluorous silane. The practicality of the sensor beads is evidenced by successfully tracking the SERS fingerprints of five food colorant standards.
Article
Materials Science, Biomaterials
Chia-Chi Huang, Yen-Shi Lai, Chih-Hsien Wang, Lai-Kwan Chau, Wenlung Chen
JOURNAL OF MATERIALS CHEMISTRY B
(2020)
Article
Chemistry, Multidisciplinary
Chia-Chi Huang, Chi-Yun Cheng, Chao-Ting Chou, Wenlung Chen
Article
Oncology
Lien-Fu Lin, Jong-Shiaw Jin, Jui-Chang Chen, Chia-Chi Huang, Jeng-Horng Sheu, Wenlung Chen, Tang-Yi Tsao, Chih-Wei Hsu
MOLECULAR AND CLINICAL ONCOLOGY
(2016)
Review
Food Science & Technology
Peiling Yan, Weiqing Lan, Jing Xie
Summary: Sodium alginate (SA) is an important marine polysaccharide that has extensive applications in food preservation and quality maintenance. Modification methods can be used to improve the properties of SA and make it compatible with other materials. Solvent-casting films and gels are common methods for using modified SA in food preservation.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Zhihui Yu, Yating Gao, Xinyi Jia, Shuai Cui, Li Ma, Dan Zheng, Xin Li, Long Li, Lixin Zhang, Yisheng Chen
Summary: This review provides a new perspective on the state-of-the-art research and application of high-intensity ultrasound (HIU) for modifying blue food proteins (BFPs). The effects of HIU treatment on the functional properties and structural composition of BFPs are comprehensively evaluated.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Review
Food Science & Technology
Honghong Zhang, Haoran Fan, Xueming Xu, Dan Xu
Summary: This review provides a comprehensive summary of changes in different components in frozen dough, including starch, gluten protein, lipid, and yeast, from a multiscale perspective. The methods of improving the production process of frozen dough, from main materials to end products, have been discussed. Key findings include the use of high gluten strength wheat flour and composite flour with high dietary fiber to improve the freezing resistance of gluten-starch matrix, as well as various methods to improve yeast freeze tolerance and the effects of different freezing rates.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Junhua Xie, Qiqiong Li, Shaoping Nie
Summary: This review provides an overview of bEVs' biology, evidence for their health benefits, and possible molecular pathways involved in their health-promoting effects, as well as perspectives for applications in foods and pharmaceuticals.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Jose Bueno-Mancebo, Adriana Artola, Raquel Barrena, Fernando Rivero-Pino
Summary: This review provides an overview of the characterization, production, and applications of sophorolipids (SLs) in the food industry. SLs exhibit bioactivity and environmental friendliness, making them suitable for various applications in food packaging, agriculture, and other areas. The importance of SLs in the context of the One Health approach is emphasized.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Letter
Food Science & Technology
Saurabh Singh
Summary: This paper is interesting and relevant to determining the moisture content of food products. However, it lacks the classification of oven drying methods, which are cost-effective and important for drying solids and semisolids.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Yong Cheng, Beijun Ang, Chaoyi Xue, Zhenyu Wang, Liduan Yin, Tong Wang, Qiuming Chen, Zhaojun Wang, Maomao Zeng, Wei Zhang, Jie Chen, Zhiyong He
Summary: Pollen fermentation can improve its nutrient profile, degrade allergenic compounds, enhance bioavailability, and promote gut health. Pollen can serve key roles in fermented food production and create opportunities for innovative product development. However, quality and safety considerations are important in pollen fermentation.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Review
Food Science & Technology
Fanghua Guo, Fereidoon Shahidi
Summary: This contribution summarizes the potential of anthocyanins as alternatives to antibiotics, focusing on their anti-oxidation, anti-inflammation, absorption, metabolism, antibacterial effects, and the possible mechanisms behind these effects. The use of encapsulation to improve stability and bioavailability of anthocyanins, as well as targeted delivery to the lower digestive tract, shows promise in replacing antibiotics. However, more in vivo studies are needed to further support these findings.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)
Article
Food Science & Technology
Muhammad Rehan Khan, Elena Torrieri, Florent Allais, Sami Fadlallah
Summary: This opinion paper explores the potential of integrating synthetic biology into microbial polymers to produce tailored biopolymers for food packaging applications. By leveraging synthetic biology tools and adopting safety assessment protocols established within the regulatory framework, this innovative approach has the potential to not only replace conventional methods but also address environmental concerns associated with traditional food packaging.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2024)