Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis in rats: Impact on TGF-β/Smad3 and NF-κB signaling pathways

Moringa seed extract alleviates titanium oxide nanoparticles (TiO2-NPs)-induced cerebral oxidative damage, and increases cerebral mitochondrial viability

(2019) Mohamed A. Kandeil et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Therapeutic Effect of Dunaliella salina Microalgae on Thioacetamide- (TAA-) Induced Hepatic Liver Fibrosis in Rats: Role of TGF-β and MMP9

(2019) Farouk K. El-Baz et al.   Biomed Research International

Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice

(2018) Tingting Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats

(2018) Ahmed M. Fayez et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin, quercetin and atorvastatin protected against the hepatic fibrosis by activating AMP-activated protein kinase

(2018) Razieh Kabirifar et al.   Journal of Functional Foods

Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via Nrf2 and NFκB regulation

(2018) Hadiya Husain et al.   Scientific Reports

A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer

(2018) Preethi Ravindranathan et al.   Scientific Reports

Ambroxol attenuates cisplatin-induced hepatotoxicity and nephrotoxicity via inhibition of p-JNK/p-ERK

(2018) Abeer Bishr et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation

(2018) Abdelazim Ibrahim et al.   Frontiers in Pharmacology

Ellagic acid protects against LPS-induced acute lung injury through inhibition of nuclear factor kappa B, proinflammatory cytokines and enhancement of interleukin-10

(2017) Shuang Guan et al.   FOOD AND AGRICULTURAL IMMUNOLOGY

Telluric Acid Ameliorates Endotoxemic Kidney Injury in Mice: Involvement of TLR4, Nrf2, and PI3K/Akt Signaling Pathways

(2017) Ahmed F. Mohamed et al.   INFLAMMATION

Protective effect of pilose antler peptide on carbon tetrachloride-induced hepatotoxicity in mice

(2017) Ma Chunhua et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anti-inflammatory and ameliorative effects of gallic acid on fluoxetine-induced oxidative stress and liver damage in rats

(2017) Omid Karimi-Khouzani et al.   Pharmacological Reports

Modulation of TGF-β/Smad and ERK signaling pathways mediates the anti-fibrotic effect of mirtazapine in mice

(2017) Dalia M. El-Tanbouly et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways

(2017) Animesh Mandal et al.   Nutrients

Ameliorative potential of rutin in combination with nimesulide in STZ model of diabetic neuropathy: targeting Nrf2/HO-1/NF-kB and COX signalling pathway

(2017) Ruchika Mittal et al.   INFLAMMOPHARMACOLOGY

Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel

(2016) Rebogile R. Mphahlele et al.   BMC Complementary and Alternative Medicine

Forskolin, a hedgehog signalling inhibitor, attenuates carbon tetrachloride-induced liver fibrosis in rats

(2016) Nermeen N El-Agroudy et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pomegranate protects liver against cecal ligation and puncture-induced oxidative stress and inflammation in rats through TLR 4 /NF‐κB pathway inhibition

(2016) Mirhan N. Makled et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Moniliformediquinone as a potential therapeutic agent, inactivation of hepatic stellate cell and inhibition of liver fibrosis in vivo

(2016) Tsui-Hwa Tseng et al.   Journal of Translational Medicine

Antifibrotic effect of meloxicam in rat liver: role of nuclear factor kappa B, proinflammatory cytokines, and oxidative stress

(2016) Memy H. Hassan et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases

(2016) Sha Li et al.   Oxidative Medicine and Cellular Longevity

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects

(2015) Ming Hong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin attenuates chronic ethanol-induced liver injury by inhibition of oxidative stress via mitogen-activated protein kinase/nuclear factor E2-related factor 2 pathway in mice

(2015) WeiGuo Dong et al.   Pharmacognosy Magazine

Protective Effect of Zingiber Officinale against CCl4-Induced Liver Fibrosis Is Mediated through Downregulating the TGF-�1/Smad3 and NF-κB/IκB Pathways

(2015) Iman H. Hasan et al.   PHARMACOLOGY

Suppression of the TGF-β/Smad signaling pathway and inhibition of hepatic stellate cell proliferation play a role in the hepatoprotective effects of curcumin against alcohol-induced hepatic fibrosis

(2014) NANZHENG CHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Modulation of thioacetamide-induced hepatic inflammations, angiogenesis and fibrosis by andrographolide in mice

(2014) Tzung-Yan Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats

(2014) Maha A.E. Ahmed et al.   LIFE SCIENCES

Protective Effect of Astaxanthin on Liver Fibrosis through Modulation of TGF-β1 Expression and Autophagy

(2014) Miao Shen et al.   MEDIATORS OF INFLAMMATION

Vinpocetine protects liver against ischemia–reperfusion injury

(2013) Hala Fahmy Zaki et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

A Review on Antihyperglycemic and Antihepatoprotective Activity of Eco-FriendlyPunica granatumPeel Waste

(2013) Sushil Kumar Middha et al.   Evidence-based Complementary and Alternative Medicine

Protective Role ofPhyllanthus niruriExtract against Thioacetamide-Induced Liver Cirrhosis in Rat Model

(2012) Zahra A. Amin et al.   Evidence-based Complementary and Alternative Medicine

Herbal Products: Benefits, Limits, and Applications in Chronic Liver Disease

(2012) Anna Del Prete et al.   Evidence-based Complementary and Alternative Medicine

Pomegranate peel and fruit extracts: A review of potential anti-inflammatory and anti-infective effects

(2012) Tariq Ismail et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ameliorative effect of grape seed proanthocyanidin extract on thioacetamide-induced mouse hepatic fibrosis

(2012) Jie Li et al.   TOXICOLOGY LETTERS

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice

(2011) Souad Mouzaoui et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Insights antifibrotic mechanism of methyl palmitate: Impact on nuclear factor kappa B and proinflammatory cytokines

(2011) Eman M. Mantawy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protective effect of Amorphophallus campanulatus (Roxb.) Blume.tuber against thioacetamide induced oxidative stress in rats

(2011) Puthuparampil Nazarudeen Ansil et al.   Asian Pacific Journal of Tropical Medicine

Comparative effects of curcumin and resveratrol on aflatoxin B1-induced liver injury in rats

(2010) Dina S. El-Agamy   ARCHIVES OF TOXICOLOGY

Protective effect of curcumin on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats: Evidence of its antioxidant property

(2010) Suresh R Naik et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

An antibody of TNF-alpha did not prevent thioacetamide-induced hepatotoxicity in rats

(2010) Ulvi Demirel et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Curcumin and the cellular stress response in free radical-related diseases

(2008) Vittorio Calabrese et al.   MOLECULAR NUTRITION & FOOD RESEARCH