Bradykinin: Inflammatory Product of the Coagulation System

Plasmin is a natural trigger for bradykinin production in patients with hereditary angioedema with factor XII mutations

(2016) Steven de Maat et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of plasminogen activator inhibitor 2 in plasma of patients with hereditary angioedema with normal C1 inhibitor levels

(2016) Kusumam Joseph et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Homozygosity for a factor XII mutation in one female and one male patient with hereditary angio-oedema

(2015) A. S. Grumach et al.   ALLERGY

Elevated D-dimers in attacks of hereditary angioedema are not associated with increased thrombotic risk

(2015) A. Reshef et al.   ALLERGY

Hereditary angioedema with normal C1-INH withversuswithout specificF12gene mutations

(2015) K. Bork et al.   ALLERGY

Idiopathic angioedema with F12 mutation: is it a new entity?

(2015) Aslı Gelincik et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Plasma contact system activation drives anaphylaxis in severe mast cell–mediated allergic reactions

(2015) Anna Sala-Cunill et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Angioedema in the neurointerventional suite

(2015) Abraham Sonny et al.   JOURNAL OF CLINICAL ANESTHESIA

Orolingual Angiodema Associated with Alteplase Treatment of Acute Stroke: A Reappraisal

(2015) Ana Sofia Correia et al.   Journal of Stroke & Cerebrovascular Diseases

Comprehensive study into the activation of the plasma enzyme systems during attacks of hereditary angioedema due to C1-inhibitor deficiency

(2015) Dorottya Csuka et al.   Orphanet Journal of Rare Diseases

Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency

(2015) Nóra Veszeli et al.   Orphanet Journal of Rare Diseases

Tranexamic acid – an old drug still going strong and making a revival

(2015) Lilian Tengborn et al.   THROMBOSIS RESEARCH

Orolingual Angiodema Associated with Alteplase Treatment of Acute Stroke: A Reappraisal

(2015) Ana Sofia Correia et al.   Journal of Stroke & Cerebrovascular Diseases

Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group

(2014) M. Cicardi et al.   ALLERGY

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

(2014) T. Zuberbier et al.   ALLERGY

High-molecular-weight kininogen cleavage correlates with disease states in the bradykinin-mediated angioedema due to hereditary C1-inhibitor deficiency

(2014) C. Suffritti et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Hereditary Angioedema Attacks: Local Swelling at Multiple Sites

(2014) Zonne L. M. Hofman et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Orolingual angioedema after alteplase therapy of acute ischaemic stroke: incidence and risk of prior angiotensin-converting enzyme inhibitor use

(2014) S.-Y. Lin et al.   EUROPEAN JOURNAL OF NEUROLOGY

Asymmetric oro-facial angioedema following alteplase for acute ischaemic stroke

(2014) Teddy Y. Wu et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Presentation, diagnosis and treatment of angioedema without wheals: a retrospective analysis of a cohort of 1058 patients

(2014) M. Mansi et al.   JOURNAL OF INTERNAL MEDICINE

Incidence, predictors and clinical characteristics of orolingual angio-oedema complicating thrombolysis with tissue plasminogen activator for ischaemic stroke

(2014) Robert Hurford et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neutrophils at work

(2014) William M Nauseef et al.   NATURE IMMUNOLOGY

Audit report and systematic review of orolingual angioedema in post-acute stroke thrombolysis

(2014) Alain Lekoubou et al.   NEUROLOGICAL RESEARCH

Angioedema after rt-PA treatment in acute ischemic stroke may be attended by shock and worsening of stroke outcome

(2014) Carlo Scialò et al.   NEUROLOGICAL SCIENCES

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angioedema From Recombinant TPA Administration

(2013) Alison Foster-Goldman et al.   AMERICAN JOURNAL OF THERAPEUTICS

Novel duplication in the F12 gene in a patient with recurrent angioedema

(2013) Nóra Kiss et al.   CLINICAL IMMUNOLOGY

Factor XII–independent activation of the bradykinin-forming cascade: Implications for the pathogenesis of hereditary angioedema types I and II

(2013) Kusumam Joseph et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Three Decades of Research on Plasminogen Activator Inhibitor-1: A Multifaceted Serpin

(2013) Ann Gils et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

A nanobody-based method for tracking factor XII activation in plasma

(2013) Steven de Maat et al.   THROMBOSIS AND HAEMOSTASIS

Structural biology of factor VIIa/tissue factor initiated coagulation

(2012) Kanagasabai Vadivel   Frontiers in Bioscience-Landmark

Hereditary angio-oedema

(2012) Hilary Longhurst et al.   LANCET

Recombinant C1-Inhibitor

(2011) Anurag Relan et al.   BIODRUGS

Alterations of coagulation and fibrinolysis in patients with angioedema due to C1-inhibitor deficiency

(2011) M. van Geffen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A novel mutation in the coagulation factor 12 gene in subjects with hereditary angioedema and normal C1-inhibitor

(2011) Konrad Bork et al.   CLINICAL IMMUNOLOGY

Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo

(2011) Chris Oschatz et al.   IMMUNITY

Cleavage of Kininogen and Subsequent Bradykinin Release by the Complement Component: Mannose-Binding Lectin-Associated Serine Protease (MASP)-1

(2011) József Dobó et al.   PLoS One

TREATMENT OF HEREDITARY ANGIONEUROTIC OEDEMA WITH TRANEXAMIC ACID

(2010) G. Blohmé   ACTA MEDICA SCANDINAVICA

Treatment of episodes of hereditary angioedema with C1 inhibitor: serial assessment of observed abnormalities of the plasma bradykinin-forming pathway and fibrinolysis

(2010) Kusumam Joseph et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Enzymatic pathways in the pathogenesis of hereditary angioedema: The role of C1 inhibitor therapy

(2010) Allen P. Kaplan   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Laminin promotes coagulation and thrombus formation in a factor XII-dependent manner

(2010) T. C. WHITE-ADAMS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Ecallantide for the Treatment of Acute Attacks in Hereditary Angioedema

(2010) Marco Cicardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Icatibant, a New Bradykinin-Receptor Antagonist, in Hereditary Angioedema

(2010) Marco Cicardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activated factor V is a cofactor for the activation of factor XI by thrombin in plasma

(2010) C. Maas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Tissue Factor and Factor VIIa in Hemostasis

(2009) Nigel Mackman   ANESTHESIA AND ANALGESIA

Dual role of collagen in factor XII-dependent thrombus formation

(2009) P. E. J. van der Meijden et al.   BLOOD

Kallikrein–kinin system and fibrinolysis in hereditary angioedema due to factor XII gene mutation Thr309Lys

(2009) Konrad Bork et al.   BLOOD COAGULATION & FIBRINOLYSIS

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Activation of the Human Contact System on Neutrophil Extracellular Traps

(2009) Sonja Oehmcke et al.   Journal of Innate Immunity

Inactivation of plasminogen activator inhibitor type 1 by activated factor XII plays a role in the enhancement of fibrinolysis by contact factors in-vitro

(2009) Aki Tanaka et al.   LIFE SCIENCES

Plasma biomarkers of acute attacks in patients with angioedema due to C1-inhibitor deficiency

(2008) M. Cugno et al.   ALLERGY

Mutational spectrum of the C1INH (SERPING1) gene in patients with hereditary angioedema

(2008) T. Göβwein et al.   CYTOGENETIC AND GENOME RESEARCH

Angioedema Incidence in US Veterans Initiating Angiotensin-Converting Enzyme Inhibitors

(2008) Donald R. Miller et al.   HYPERTENSION