Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients

Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review

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Polypharmacy and major adverse events in atrial fibrillation: observations from the AFFIRM trial

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The burden of disease in older people and implications for health policy and practice

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Changes in clinical outcomes for community-dwelling older people exposed to incident chronic polypharmacy: a comparison between 2001 and 2009

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Safety and Benefit of Discontinuing Statin Therapy in the Setting of Advanced, Life-Limiting Illness

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Acute coronary syndromes in octogenarians referred for invasive evaluation: treatment profile and outcomes

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Analyses of drugs stored at home by elderly patients with chronic heart failure

(2014) Sebastian Ewen et al.   Clinical Research in Cardiology

Personalized cardiovascular disease prevention by applying individualized prediction of treatment effects

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Development and Validation of a Coronary Risk Prediction Model for Older U.S. and European Persons in the Cardiovascular Health Study and the Rotterdam Study

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Secondary Prevention of Atherosclerotic Cardiovascular Disease in Older Adults

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2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

(2013) Neil J. Stone et al.   CIRCULATION

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

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Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)

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A Score for the Prediction of Cardiovascular Events in the Hypertensive Aged

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Polypharmacy in the Elderly

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The Anglo-Scandinavian Cardiac Outcomes Trial: 11-year mortality follow-up of the lipid-lowering arm in the UK

(2011) Peter S. Sever et al.   EUROPEAN HEART JOURNAL

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Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

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(2009) Marcel Wolbers et al.   EPIDEMIOLOGY

Concomitant use of statins and CYP3A4 inhibitors in administrative claims and electronic medical records databases

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