AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4

MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis

(2014) Jian-Wen Yu et al.   LABORATORY INVESTIGATION

Tamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis

(2014) Jesús Loureiro et al.   PLoS One

TGF- 1 Promotes Lymphangiogenesis during Peritoneal Fibrosis

(2013) H. Kinashi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-β1 signaling

(2013) Toshinori Ueno et al.   KIDNEY INTERNATIONAL

Disruption of Smad7 Promotes ANG II-Mediated Renal Inflammation and Fibrosis via Sp1-TGF-β/Smad3-NF.κB-Dependent Mechanisms in Mice

(2013) Guan-Xian Liu et al.   PLoS One

Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer

(2013) Long Zhang et al.   TRENDS IN BIOCHEMICAL SCIENCES

Overexpression of Smad ubiquitin regulatory factor 2 suppresses transforming growth factor-β mediated liver fibrosis

(2012) Yu CAI et al.   Journal of Digestive Diseases

Ubiquitin removal in the TGF-β pathway

(2012) Kamna Aggarwal et al.   NATURE CELL BIOLOGY

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

(2012) Long Zhang et al.   NATURE CELL BIOLOGY

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

(2012) Pieter J A Eichhorn et al.   NATURE MEDICINE

Smad7 gene transfer attenuates angiogenesis in peritoneal dialysis rats

(2012) Weisheng Peng et al.   NEPHROLOGY

A Crosstalk between the Smad and JNK Signaling in the TGF-β-Induced Epithelial-Mesenchymal Transition in Rat Peritoneal Mesothelial Cells

(2012) Qinghua Liu et al.   PLoS One

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways

(2012) Eric Aragón et al.   STRUCTURE

CD109-mediated degradation of TGF-β receptors and inhibition of TGF-β responses involve regulation of SMAD7 and Smurf2 localization and function

(2011) Albane A. Bizet et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma

(2011) Olorunseun O Ogunwobi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Blocking TGF- 1 Protects the Peritoneal Membrane from Dialysate-Induced Damage

(2011) J. Loureiro et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis

(2011) Hideki Yokoi et al.   KIDNEY INTERNATIONAL

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways

(2011) Xiao-Feng Chen et al.   MOLECULAR BIOLOGY REPORTS

Thyroid hormone potentiates insulin
 signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes

(2010) Yi Lin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epithelial–mesenchymal transition of rat peritoneal mesothelial cells via Rhoa/Rock pathway

(2010) Hao Zhang et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Focal adhesion kinase mediates TGF-β1-induced renal tubular epithelial-to-mesenchymal transition in vitro

(2010) Bingqing Deng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Phosphatidylinositol 3-Kinase/Akt Pathway Regulates Transforming Growth Factor-β Signaling by Destabilizing Ski and Inducing Smad7

(2009) Arja M. Band et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Smad7 as a therapeutic agent for chronic kidney diseases

(2008) Hui Yao Lan   Frontiers in Bioscience-Landmark

Insulin attenuates apoptosis induced by high glucose via the PI3-kinase/Akt pathway in rat peritoneal mesothelial cells

(2008) K. Kaifu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Involvement of PI3K/Akt Pathway in TGF-β2-Mediated Epithelial Mesenchymal Transition in Human Lens Epithelial Cells

(2008) Ke Yao et al.   OPHTHALMIC RESEARCH