Article
Microbiology
Alessandra Pino, Tommaso Mazza, Maura-Ann H. Matthews, Stefano Castellana, Cinzia Caggia, Cinzia L. Randazzo, Gary A. Gelbfish
Summary: Gardnerella species are key players in the development and recurrence of Bacterial Vaginosis (BV), often showing high resistance to antibiotics. Bovine lactoferrin may be a potential candidate for treating Gardnerella species infection.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Fisheries
Wang-Jing Liu, Yun-Shiang Chang, Kou-Chun Tseng, Meng-Hua Yu
Summary: White spot syndrome virus (WSSV) is a prominent pathogen in shrimp farming worldwide. However, there is currently no effective treatment for this virus. In this study, the antiviral properties of bovine lactoferrin (bLF) against WSSV were investigated, and it was found that bLF treatment significantly reduced shrimp mortalities caused by WSSV infection. The ability of bLF to bind to both host cells and WSSV virions suggests its potential as an anti-WSSV agent in shrimp culture, and the identified interaction proteins may play a role in WSSV infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Mohammad Javad Taghipour, Hamid Ezzatpanah, Mohammad Ghahderijani
Summary: This study isolated camel milk protein fractions and hydrolyzed them using enzymes, finding peptides with anticancer and antibacterial activities. Two promising peptides, P3 and P5, showed low binding energy and inhibition constant, making them potential drug candidates.
Article
Chemistry, Applied
Huijuan Jing, Xin Huang, Chao Jiang, Li Wang, Xiaojing Du, Chaoyang Ma, Hongxin Wang
Summary: The study showed that tannic acid could form stable complexes with bovine lactoferrin, resulting in a compact structure at a specific molar ratio. The addition of tannic acid reduced the digestibility of lactoferrin, suggesting a potential improvement in digestive stability of bio-complexes.
FOOD HYDROCOLLOIDS
(2021)
Article
Pharmacology & Pharmacy
Tzu-Ching Lin, Chun-Yin Yang, Tzu-Hui Wu, Chih-Hua Tseng, Feng-Lin Yen
Summary: This study developed a MyNF system of HPBCD/PVP to enhance the water solubility and skin penetration of MYR through changing its physicochemical characteristics. The results showed that MyNF reduced cytotoxicity in HaCaT keratinocytes compared to MYR, and had better antioxidant and photoprotective activity. In conclusion, MyNF is a safe and stable antioxidant nanofibers that can enhance the skin penetration of MYR and prevent UVB-induced skin damage.
Article
Food Science & Technology
Yao Lu, Yixuan Li, Yingying Lin, Jingxuan Wang, Mengjuan Ma, Huiyuan Guo
Summary: Lactoferrin (LF) has the potential to improve skeletal health by stimulating osteoblast proliferation and differentiation. However, LF is sensitive to thermal processing and hydrolysis in the gastrointestinal tract, impacting its osteogenic activity. This study found that LF treated at 72 degrees C/15 s showed the least structural alteration and retained the osteogenesis-promoting effect. Furthermore, LF hydrolysates from intestinal digestion showed a stronger effect on osteoblast differentiation independent of specific signaling pathways.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Qili Zhang, Yanfang Zhao, Meiyan Zhang, Yalu Zhang, Hongfang Ji, Liang Shen
Summary: Vine tea, a traditional Chinese herbal tea rich in flavonoids, exhibits a wide range of significant bioactivities that contribute to its potential health benefits and role in disease prevention and therapy. Research focuses on exploring the bioactive constituents, pharmacological effects, and possible mechanisms of vine tea.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2021)
Article
Biochemistry & Molecular Biology
Yan Chen, Xuefeng Gao, Bin Li, Jing Tian
Summary: The study investigated the effects of the interaction between konjac glucomannan (KGM) and dihydromyricetin (DMY) on KGM's viscosity, hydration capacity, and DMY's thermal stability. Contrary to most reports, adding DMY to KGM increased viscosity and hydration capacity and improved DMY's retention and radical scavenging capacity under heating conditions. The KGM-DMY complex was characterized as a non-covalent compound connected by hydrogen bonds. This study is beneficial for the development of polyphenol-enriched nutrition based on KGM, particularly in terms of satiety, appetite regulation, and glucose regulation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Multidisciplinary Sciences
Emanuel L. Peter, Prakash B. Nagendrappa, Clement Olusoji Ajayi, Crispin Duncan Sesaazi
Summary: Optimal extraction conditions for polyphenols from Abelmoschus esculentus fruits were determined using Response Surface Methodology, and the extract showed promising antihyperglycemic activity in a diabetic rat model.
Article
Fisheries
Mona M. Abdel-Wahab, Nabil M. Taha, Mohamed A. Lebda, Mohamed S. Elfeky, Hany M. R. Abdel-Latif
Summary: The study showed that dietary supplementation with BLF or CHN alone or in combinations can significantly improve antioxidative status and immunity, enhancing the disease resistance of Nile tilapia.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Review
Pharmacology & Pharmacy
Magda Reyes-Lopez, Gerardo Ramirez-Rico, Jesus Serrano-Luna, Mireya de la Garza
Summary: Parasites and other pathogens must adapt to the host's environment to survive. Lactoferrin (Lf) is a host protein that acts as a defense mechanism in the innate immune system. This study reviews the activity of Lf against various parasitic pathogens, including sequestering iron ions needed for survival and producing reactive oxygen species.
Article
Food Science & Technology
Baoshuang Du, Shan Wang, Song Zhu, Yue Li, Dejian Huang, Shangwei Chen
Summary: In this study, the liposolubility of dihydromyricetin (DHM) was improved by acylating it with different fatty acid vinyl esters, resulting in the synthesis of five DHM acylated derivatives with different carbon chain lengths and lipophilicity. The relationship between the lipophilicity and antioxidant activities of DHM and its derivatives was evaluated using oil and emulsion models. The results showed that DHM derivatives with different lipophilicity exhibited various antioxidant activities in different antioxidant models.
Article
Chemistry, Applied
Mengyuan Wang, Jinhui Xu, Tinglu Han, Lin Tang
Summary: The interaction between theaflavins and bovine lactoferrin leads to structural changes, with TFDG having a certain impact on the functionality of bovine lactoferrin.
Article
Cell Biology
Xingchi Kan, Juxiong Liu, Yingsheng Chen, Wenjin Guo, Dianwen Xu, Ji Cheng, Yu Cao, Zhanqing Yang, Shoupeng Fu
Summary: Research shows that myricetin can effectively alleviate oxidative stress and apoptosis by activating the AMPK/NRF2 signaling pathway. This may provide a new therapeutic strategy for protecting high-producing dairy cows' mammary epithelial cells.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Reem N. El Gammal, Heba Elmansi, Ali A. El-Emam, Fathalla Belal, Mohammed E. A. Hammouda
Summary: This study investigates the binding interaction between mebendazole and bovine serum albumin using different techniques. The results suggest that the interaction is static and endothermic, with intermolecular hydrophobic forces playing a crucial role in stabilizing the drug-protein system.
SCIENTIFIC REPORTS
(2022)
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)