Radioactive 125I seeds inhibit cell growth and epithelial-mesenchymal transition in human glioblastoma multiforme via a ROS-mediated signaling pathway

PAK1 Tyrosine Phosphorylation Is Required to Induce Epithelial-Mesenchymal Transition and Radioresistance in Lung Cancer Cells

(2014) E. Kim et al.   CANCER RESEARCH

Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity

(2013) Fang Wu et al.   BMC CANCER

Understanding high grade glioma: Molecular mechanism, therapy and comprehensive management

(2013) Yongzhi Wang et al.   CANCER LETTERS

Interstitial brachytherapy with iodine-125 seeds for low grade brain stem gliomas in adults: Diagnostic and therapeutic intervention in a one-step procedure

(2013) William Omar Contreras Lopez et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes

(2013) Roberto Gomez-Casal et al.   Molecular Cancer

Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma

(2013) Roshan Mahabir et al.   NEURO-ONCOLOGY

Radioactive 125I Seed Inhibits the Cell Growth, Migration, and Invasion of Nasopharyngeal Carcinoma by Triggering DNA Damage and Inactivating VEGF-A/ERK Signaling

(2013) Yunhong Tian et al.   PLoS One

The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art

(2012) Mike De Vos et al.   BIOCHEMICAL PHARMACOLOGY

Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma

(2012) Cardin Romilda et al.   BMC CANCER

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

(2012) Alexandria M Haslehurst et al.   BMC CANCER

Permanent Implantation of Iodine-125 Seeds as a Salvage Therapy for Recurrent Head and Neck Carcinoma After Radiotherapy

(2012) Na Meng et al.   CANCER INVESTIGATION

Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas

(2012) U.D. Kahlert et al.   CANCER LETTERS

Intracellular distribution and mechanisms of actions of photosensitizer Zinc(II)-phthalocyanine solubilized in Cremophor EL against human hepatocellular carcinoma HepG2 cells

(2012) Jingwei Shao et al.   CANCER LETTERS

Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint

(2012) Tohru Yamamori et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gamma-ray Irradiation Impairs Dendritic Cell Migration to CCL19 by Down-regulation of CCR7 and Induction of Cell Apoptosis

(2012) Cong Liu et al.   International Journal of Biological Sciences

Tankyrase-targeted therapeutics: expanding opportunities in the PARP family

(2012) Jenna L. Riffell et al.   NATURE REVIEWS DRUG DISCOVERY

Oxidative stress and antioxidant status in primary bone and soft tissue sarcoma

(2011) Fatima M Nathan et al.   BMC CANCER

Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury

(2011) Edouard I. Azzam et al.   CANCER LETTERS

Stereotactic Brachytherapy With Iodine-125 Seeds for the Treatment of Inoperable Low-Grade Gliomas in Children: Long-Term Outcome

(2011) Maximilian I. Ruge et al.   JOURNAL OF CLINICAL ONCOLOGY

High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) R. Stupp et al.   ANNALS OF ONCOLOGY

Percutaneous computed tomography/ultrasonography-guided permanent iodine-125 implantation as salvage therapy for recurrent squamous cell cancers of head and neck

(2010) Yu-Liang Jiang et al.   CANCER BIOLOGY & THERAPY

Relative Biological Effectiveness and Cell-Killing Efficacy of Continuous Low-Dose-Rate 125I Seeds on Prostate Carcinoma Cells In Vitro

(2010) Anyan Liao et al.   INTEGRATIVE CANCER THERAPIES

Regulation of Lung Cancer Cell Migration and Invasion by Reactive Oxygen Species and Caveolin-1

(2010) Sudjit Luanpitpong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of dose escalation with intracavitary brachytherapy in the treatment of localized CNS malignancies: Outcomes and toxicities of a prospective study

(2009) A. Gabriella Wernicke et al.   Brachytherapy

The Direct Biologic Effects of Radioactive 125I Seeds on Pancreatic Cancer Cells PANC-1, at Continuous Low-Dose Rates

(2009) Jidong Wang et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Trihydrophobin 1 Interacts with PAK1 and Regulates ERK/MAPK Activation and Cell Migration

(2009) Chunming Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The biological effect of 125I seed continuous low dose rate irradiation in CL187 cells

(2009) Hong-Qing Zhuang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Selenocystine induces reactive oxygen species–mediated apoptosis in human cancer cells

(2008) Tianfeng Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Interstitial permanent implantation of 125I seeds as salvage therapy for re-recurrent rectal carcinoma

(2008) Jun Jie Wang et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Safety and efficacy of permanent iodine-125 seed implants and carmustine wafers in patients with recurrent glioblastoma multiforme

(2008) Borimir J. Darakchiev et al.   JOURNAL OF NEUROSURGERY

Elevated DNA damage in a mouse model of oxidative stress: impacts of ionizing radiation and a protective dietary supplement

(2008) J. A. Lemon et al.   MUTAGENESIS