Ascorbic acid and ascorbate-2-phosphate decrease HIF activity and malignant properties of human melanoma cells

Melanoma: Diagnosis, Staging, and Treatment. Consensus group recommendations

(2014) Alfonso Berrocal et al.   ADVANCES IN THERAPY

Current management of advanced melanoma: a transformed landscape

(2014) David E. Gyorki et al.   ANZ JOURNAL OF SURGERY

Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response

(2014) Caroline Kuiper et al.   FREE RADICAL BIOLOGY AND MEDICINE

Association Between Dietary Vitamin C and Risk of Cutaneous Melanoma in a Population of Northern Italy

(2014) Marcella Malavolti et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Intravenous ascorbic acid as an adjuvant to interleukin-2 immunotherapy

(2014) Samuel C Wagner et al.   Journal of Translational Medicine

Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer

(2014) Caroline Kuiper et al.   Frontiers in Oncology

Novel Targets in the Treatment of Advanced Melanoma: New First-Line Treatment Options

(2013) Kathryn A Culos et al.   ANNALS OF PHARMACOTHERAPY

HIF1α and HIF2α independently activate SRC to promote melanoma metastases

(2013) Sara C. Hanna et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery of small molecule cancer drugs: Successes, challenges and opportunities

(2012) Swen Hoelder et al.   Molecular Oncology

Narrowing the knowledge gaps for melanoma

(2012) Ana Slipicevic et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Vitamin C: A Concentration-Function Approach Yields Pharmacology and Therapeutic Discoveries

(2012) Mark Levine et al.   Advances in Nutrition

Guidelines of care for the management of primary cutaneous melanoma

(2011) Christopher K. Bichakjian et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

(2010) S Y Nam et al.   BRITISH JOURNAL OF CANCER

Low Ascorbate Levels Are Associated with Increased Hypoxia-Inducible Factor-1 Activity and an Aggressive Tumor Phenotype in Endometrial Cancer

(2010) C. Kuiper et al.   CANCER RESEARCH

Constitutive HIF-1 activity in malignant melanoma

(2010) Silke Kuphal et al.   EUROPEAN JOURNAL OF CANCER

High levels of oxidative stress in patients with advanced lung cancer

(2010) Hidir ESME et al.   RESPIROLOGY

Prognostic relevance of hypoxia inducible factor-1α expression in patients with melanoma

(2009) J. Valencak et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions

(2009) Caroline N Mills et al.   Molecular Cancer

Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin

(2009) Barbara Bedogni et al.   Pigment Cell & Melanoma Research

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

(2007) K. Takeda et al.   BLOOD