Vitamin C: A Concentration-Function Approach Yields Pharmacology and Therapeutic Discoveries

High dose of ascorbic acid induces cell death in mesothelioma cells

(2010) Yukitoshi Takemura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

(2010) J. Du et al.   CLINICAL CANCER RESEARCH

Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice

(2010) Christopher P. Corpe et al.   JOURNAL OF CLINICAL INVESTIGATION

Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension

(2010) James M. Roberts et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects

(2010) Sebastian J. Padayatty et al.   PLoS One

Vitamin C: working on the x-axis

(2009) Mark Levine et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials

(2009) Jens Lykkesfeldt et al.   BRITISH JOURNAL OF NUTRITION

Comment re: Vitamin C Antagonizes the Cytotoxic Effects of Chemotherapy

(2009) M. G. Espey et al.   CANCER RESEARCH

Bortezomib, ascorbic acid and melphalan (BAM) therapy for patients with newly diagnosed multiple myeloma: an effective and well-tolerated frontline regimen

(2009) James R. Berenson et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Depletion of l-ascorbic acid alternating with its supplementation in the treatment of patients with acute myeloid leukemia or myelodysplastic syndromes

(2009) Chan H. Park et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects

(2009) Julien Verrax et al.   FREE RADICAL BIOLOGY AND MEDICINE

Losing and finding a way at C: New promise for pharmacologic ascorbate in cancer treatment

(2009) Mark Levine et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant Supplements and Cardiovascular Disease in Men

(2009) Sebastian J. Padayatty   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis

(2009) Chang-Hwan Yeom et al.   Journal of Translational Medicine

Effect of ascorbic acid in patients with Charcot–Marie–Tooth disease type 1A: a multicentre, randomised, double-blind, placebo-controlled trial

(2009) Joëlle Micallef et al.   LANCET NEUROLOGY

Ascorbic acid inhibits antitumor activity of bortezomib in vivo

(2009) G Perrone et al.   LEUKEMIA

Oxalic acid excretion after intravenous ascorbic acid administration

(2009) Line Robitaille et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Antiproliferative Effect of Ascorbic Acid Is Associated with the Inhibition of Genes Necessary to Cell Cycle Progression

(2009) Sophie Belin et al.   PLoS One

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy

(2008) L. J. Hoffer et al.   ANNALS OF ONCOLOGY

The controversial place of vitamin C in cancer treatment

(2008) J. Verrax et al.   BIOCHEMICAL PHARMACOLOGY

Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs

(2008) M. L. Heaney et al.   CANCER RESEARCH

Vitamins E and C in the Prevention of Cardiovascular Disease in Men

(2008) Howard D. Sesso   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficacy of Parenteral Nutrition Supplemented With Glutamine Dipeptide to Decrease Hospital Infections in Critically Ill Surgical Patients

(2008) Concepción F. Estívariz et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

(2008) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA