Dexmedetomidine Attenuates LPS-Induced Monocyte-Endothelial Adherence via Inhibiting Cx43/PKC-α/NOX2/ROS Signaling Pathway in Monocytes

The vitamin B6-dependent enzymes PYGL and G6PD fuel NADPH oxidases to promote skin inflammation

(2020) Francisco J. Martínez-Navarro et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Trimethylamine N‐oxide promotes apoE −/− mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway

(2020) Peng Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dexmedetomidine Attenuates Monocyte-Endothelial Adherence via Inhibiting Connexin43 on Vascular Endothelial Cells

(2020) Yunfei Chai et al.   MEDIATORS OF INFLAMMATION

Aloin Inhibits the Proliferation and Migration of Gastric Cancer Cells by Regulating NOX2–ROS-Mediated Pro-Survival Signal Pathways

(2020) Ziqian Wang et al.   Drug Design Development and Therapy

MyD88-dependent influx of monocytes and neutrophils impairs lymph node B cell responses to chikungunya virus infection via Irf5, Nos2 and Nox2

(2020) Mary K. McCarthy et al.   PLoS Pathogens

Causes of late mortality among ICU‐treated patients with sepsis

(2020) Susanne B. Wilhelms et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

IL-20 promotes hypoxia/reoxygenation-induced mitochondrial dysfunction and apoptosis in cardiomyocytes by upregulating oxidative stress by activating the PKC/NADPH oxidase pathway

(2020) Kun-Ling Tsai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pulmonary microbiome patterns correlate with the course of the disease in patients with sepsis-induced ARDS following major abdominal surgery

(2020) Felix C.F. Schmitt et al.   JOURNAL OF HOSPITAL INFECTION

Down-regulation of Cx43 expression on PIH-HUVEC cells attenuates monocyte–endothelial adhesion

(2019) Xianlong Li et al.   THROMBOSIS RESEARCH

Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy

(2019) Yanyan Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Propofol attenuates monocyte-endothelial adhesion via modulating connexin43 expression in monocytes

(2019) Haocong Ji et al.   LIFE SCIENCES

Inhibition of gap junction composed of Cx43 prevents against acute kidney injury following liver transplantation

(2019) Dongdong Yuan et al.   Cell Death & Disease

Adverse Hemodynamic Events Associated With Concomitant Dexmedetomidine and Propofol for Sedation in Mechanically Ventilated ICU Patients

(2019) Mitchell S. Buckley et al.   JOURNAL OF INTENSIVE CARE MEDICINE

The Effect Of Intraoperative Use Of Dexmedetomidine During The Daytime Operation Vs The Nighttime Operation On Postoperative Sleep Quality And Pain Under General Anesthesia

(2019) Bijia Song et al.   Nature and Science of Sleep

Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU

(2019) Jarett V. Pereira et al.   EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Resveratrol prevents nanoparticles-induced inflammation and oxidative stress via downregulation of PKC-α and NADPH oxidase in lung epithelial A549 cells

(2018) Hung-Te Hsu et al.   BMC Complementary and Alternative Medicine

ROS signaling and ER stress in cardiovascular disease

(2018) Cristhiaan D. Ochoa et al.   MOLECULAR ASPECTS OF MEDICINE

The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders

(2018) Anuradha Tarafdar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human Peritoneal Mesothelial Cell Death Induced by High-Glucose Hypertonic Solution Involves Ca2+ and Na+ Ions and Oxidative Stress with the Participation of PKC/NOX2 and PI3K/Akt Pathways

(2017) Felipe Simon et al.   Frontiers in Physiology

Caffeic acid phenethyl ester suppresses monocyte adhesion to the endothelium by inhibiting NF-κB/NOX2-derived ROS signaling

(2016) Risa Nakahara et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Propofol attenuated liver transplantation-induced acute lung injury via connexin43 gap junction inhibition

(2016) Dongdong Yuan et al.   Journal of Translational Medicine

Targeting the ROS-HIF-1-endothelin axis as a therapeutic approach for the treatment of obstructive sleep apnea-related cardiovascular complications

(2016) Elise Belaidi et al.   PHARMACOLOGY & THERAPEUTICS

Salusin-β induces foam cell formation and monocyte adhesion in human vascular smooth muscle cells via miR155/NOX2/NFκB pathway

(2016) Hai-Jian Sun et al.   Scientific Reports

Dexmedetomidine protects against apoptosis induced by hypoxia/reoxygenation through the inhibition of gap junctions in NRK-52E cells

(2015) Chenfang Luo et al.   LIFE SCIENCES

ROS Production via P2Y1-PKC-NOX2 Is Triggered by Extracellular ATP after Electrical Stimulation of Skeletal Muscle Cells

(2015) Alexis Díaz-Vegas et al.   PLoS One

Monocyte–endothelial adhesion is modulated by Cx43-stimulated ATP release from monocytes

(2012) Dongdong Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hyperketonemia induces upregulation of LFA-1 in monocytes, which is mediated by ROS and P38 MAPK activation

(2012) Justin L. Rains et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

(2012) Chih-Chung Lin et al.   Cell Communication and Signaling

Targeting Cx43 and N-Cadherin, Which Are Abnormally Upregulated in Venous Leg Ulcers, Influences Migration, Adhesion and Activation of Rho GTPases

(2012) Ariadna Mendoza-Naranjo et al.   PLoS One

STAT1-mediated signal integration between IFNγ and LPS leads to increased EC and SMC activation and monocyte adhesion

(2011) Krzysztof Sikorski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Monocyte trafficking in acute and chronic inflammation

(2011) Molly A. Ingersoll et al.   TRENDS IN IMMUNOLOGY