Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line

Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer

(2019) Patrycja Nowak-Sliwinska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Antitumour effects of metformin and curcumin in human papillomavirus positive and negative head and neck cancer cells

(2019) Cameron Lindsay et al.   MOLECULAR CARCINOGENESIS

The relationship between molecular content of mesenchymal stem cells derived exosomes and their potentials: Opening the way for exosomes based therapeutics

(2019) Davod Jafari et al.   BIOCHIMIE

Inhibitor of the human telomerase reverse trancriptase (hTERT) gene promoter induces cell apoptosis via a mitochondrial-dependent pathway

(2018) Yuyin Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The inhibitory effects of nano-encapsulated metformin on growth and hTERT expression in breast cancer cells

(2018) Shahrzad Javidfar et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways

(2018) Yan Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Constructing and transient expression of a gene cassette containing edible vaccine elements and shigellosis, anthrax and cholera recombinant antigens in tomato

(2018) Jafari Davod et al.   MOLECULAR BIOLOGY REPORTS

Effects of fungal extracts on vinblastine and vincristine production and their biosynthesis pathway genes in Catharanthus roseus

(2018) A. Ramezani et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Studies on combination of oxaliplatin and dendrosomal nanocurcumin on proliferation, apoptosis induction, and long non-coding RNA expression in ovarian cancer cells

(2018) Elahe Seyed Hosseini et al.   CELL BIOLOGY AND TOXICOLOGY

Curcumin-primed and curcumin-loaded exosomes: potential neural therapy

(2017) Anuradha Kalani et al.   Neural Regeneration Research

Metformin: a review of its potential indications

(2017) Yi-Wei Wang et al.   Drug Design Development and Therapy

Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models

(2017) Ying Li et al.   Oncotarget

Combination therapy in combating cancer

(2017) Reza Bayat Mokhtari et al.   Oncotarget

Nano-encapsulated metformin-curcumin in PLGA/PEG inhibits synergistically growth and hTERT gene expression in human breast cancer cells

(2017) Raana Farajzadeh et al.   Artificial Cells Nanomedicine and Biotechnology

Metformin inhibits prostate cancer cell proliferation, migration, and tumor growth through upregulation of PEDF expression

(2016) Xiaowan Chen et al.   CANCER BIOLOGY & THERAPY

Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa

(2016) Hossam Murad et al.   Cancer Cell International

Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death

(2016) Kai Wang et al.   Scientific Reports

Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair

(2015) Maryam Mohajeri et al.   NEUROPHARMACOLOGY

Encapsulation of Curcumin in Diblock Copolymer Micelles for Cancer Therapy

(2015) Ali Mohammad Alizadeh et al.   Biomed Research International

Curcumin triggers apoptosis via upregulation of Bax/Bcl-2 ratio and caspase activation in SW872 human adipocytes

(2015) LIN ZHU et al.   Molecular Medicine Reports

Curcumin in various cancers

(2013) Adeeb Shehzad et al.   BIOFACTORS

Curcumin, a component of turmeric: From farm to pharmacy

(2013) Subash C. Gupta et al.   BIOFACTORS

Prostate Cancer: Current Treatment and Prevention Strategies

(2013) Fang-zhi Chen et al.   Iranian Red Crescent Medical Journal

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

(2011) Bolin Liu et al.   CELL CYCLE

Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth

(2011) G. Z. Rocha et al.   CLINICAL CANCER RESEARCH

RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells

(2011) LINHU GE et al.   Oncology Letters

Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2

(2010) Ying Qiang ZHONG et al.   Journal of Digestive Diseases

Natural products for cancer chemotherapy

(2010) Arnold L. Demain et al.   Microbial Biotechnology

Metformin is a potent inhibitor of endometrial cancer cell proliferation—implications for a novel treatment strategy

(2009) Leigh A. Cantrell et al.   GYNECOLOGIC ONCOLOGY

Outcomes of Localized Prostate Cancer Following Conservative Management

(2009) Grace L. Lu-Yao   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Recommandations pour la prise en charge du cancer de la prostate chez l’homme âgé : un travail du comité de cancérologie de l’association française d’urologie

(2009) P. Mongiat-Artus et al.   PROGRES EN UROLOGIE

The multi-disciplinary management of high-risk prostate cancer

(2009) Jonathan C. Picard et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Metformin therapy and clinical uses

(2008) John HB Scarpello et al.   Diabetes & Vascular Disease Research

In vitro metformin anti-neoplastic activity in epithelial ovarian cancer

(2008) Walter H. Gotlieb et al.   GYNECOLOGIC ONCOLOGY

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

(2008) I Ben Sahra et al.   ONCOGENE

mTOR—What Does It Do?

(2008) M.N. Hall   TRANSPLANTATION PROCEEDINGS