Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation
Authors
Keywords
-
Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-08-11
DOI
10.1038/s41594-020-0471-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
- (2020) Thomas C. T. Michaels et al. Nature Chemistry
- A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease
- (2019) Francesco Panza et al. Nature Reviews Neurology
- Amyloid-β oligomers have a profound detergent-like effect on lipid membrane bilayers, imaged by atomic force and electron microscopy
- (2019) David C. Bode et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation
- (2018) Thomas C.T. Michaels et al. Annual Review of Physical Chemistry
- Secondary nucleation in amyloid formation
- (2018) Mattias Törnquist et al. CHEMICAL COMMUNICATIONS
- Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
- (2018) Chao Peng et al. NATURE
- Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes
- (2017) Wei Qiang et al. NATURE
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
- (2017) Giuliana Fusco et al. SCIENCE
- Seed-induced acceleration of amyloid-β mediated neurotoxicity in vivo
- (2017) Ramona F. Sowade et al. Nature Communications
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
- (2016) Jeff Sevigny et al. NATURE
- Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease
- (2016) Johnny Habchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct High Affinity Interaction between Aβ42 and GSK3α Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer’s Disease?
- (2015) Christopher J. Dunning et al. ACS Chemical Neuroscience
- Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
- (2015) Zane Jaunmuktane et al. NATURE
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
- (2014) Cecilia Månsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism
- (2013) S. I. A. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
- (2012) Nunilo Cremades et al. CELL
- High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C
- (2012) H. Willander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prion propagation and toxicity in vivo occur in two distinct mechanistic phases
- (2011) Malin K. Sandberg et al. NATURE
- A causative link between the structure of aberrant protein oligomers and their toxicity
- (2010) Silvia Campioni et al. Nature Chemical Biology
- Peripherally Applied A -Containing Inoculates Induce Cerebral -Amyloidosis
- (2010) Y. S. Eisele et al. SCIENCE
- Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process
- (2009) Erik Hellstrand et al. ACS Chemical Neuroscience
- A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide
- (2009) Dominic M. Walsh et al. FEBS Journal
- An Analytical Solution to the Kinetics of Breakable Filament Assembly
- (2009) T. P. J. Knowles et al. SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started