Recent advances in neural interfaces—Materials chemistry to clinical translation

In vivo imaging of calcium and glutamate responses to intracortical microstimulation reveals distinct temporal responses of the neuropil and somatic compartments in layer II/III neurons

(2020) James R. Eles et al.   BIOMATERIALS

Development of a neural interface for high-definition, long-term recording in rodents and nonhuman primates

(2020) Chia-Han Chiang et al.   Science Translational Medicine

Massively parallel microwire arrays integrated with CMOS chips for neural recording

(2020) Abdulmalik Obaid et al.   Science Advances

Revealing Spatial and Temporal Patterns of Cell Death, Glial Proliferation, and Blood-Brain Barrier Dysfunction Around Implanted Intracortical Neural Interfaces

(2019) Steven M. Wellman et al.   Frontiers in Neuroscience

Intracortical Neural Stimulation With Untethered, Ultrasmall Carbon Fiber Electrodes Mediated by the Photoelectric Effect

(2019) Kaylene C. Stocking et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

The business of brain–computer interfaces

(2019) Eric Smalley   NATURE BIOTECHNOLOGY

A Critical Review of Microelectrode Arrays and Strategies for Improving Neural Interfaces

(2019) Morgan Ferguson et al.   Advanced Healthcare Materials

Chronically implanted Neuropixels probes enable high-yield recordings in freely moving mice

(2019) Ashley L Juavinett et al.   eLife

An Integrated Brain-Machine Interface Platform With Thousands of Channels

(2019) Elon Musk et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Zwitterionic polymer/polydopamine coating reduce acute inflammatory tissue responses to neural implants

(2019) Asiyeh Golabchi et al.   BIOMATERIALS

Neuropixels Data-Acquisition System: A Scalable Platform for Parallel Recording of 10 000+ Electrophysiological Signals

(2019) Jan Putzeys et al.   IEEE Transactions on Biomedical Circuits and Systems

The frequency of cortical microstimulation shapes artificial touch

(2019) Thierri Callier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stretchable Seal

(2018) Paul Le Floch et al.   ACS Applied Materials & Interfaces

Ultracompliant Hydrogel-Based Neural Interfaces Fabricated by Aqueous-Phase Microtransfer Printing

(2018) Wei-Chen Huang et al.   ADVANCED FUNCTIONAL MATERIALS

In vivo spatiotemporal dynamics of NG2 glia activity caused by neural electrode implantation

(2018) Steven M. Wellman et al.   BIOMATERIALS

In vivo imaging of neuronal calcium during electrode implantation: Spatial and temporal mapping of damage and recovery

(2018) James R. Eles et al.   BIOMATERIALS

Acute in vivo testing of a conformal polymer microelectrode array for multi-region hippocampal recordings

(2018) Huijing Xu et al.   Journal of Neural Engineering

Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface

(2018) Nicholas J Michelson et al.   Journal of Neural Engineering

Proprioceptive and cutaneous sensations in humans elicited by intracortical microstimulation

(2018) Michelle Armenta Salas et al.   eLife

Characterization of the Neuroinflammatory Response to Thiol-ene Shape Memory Polymer Coated Intracortical Microelectrodes

(2018) Andrew Shoffstall et al.   Micromachines

Softening Shape Memory Polymer Substrates for Bioelectronic Devices With Improved Hydrolytic Stability

(2018) Seyed Mahmoud Hosseini et al.   Frontiers in Materials

Micro-CT and Histological Evaluation of an Neural Interface Implanted Within a Blood Vessel

(2017) Nicholas Lachlan Opie et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Histological evaluation of flexible neural implants; flexibility limit for reducing the tissue response?

(2017) Heui Chang Lee et al.   Journal of Neural Engineering

Fully integrated silicon probes for high-density recording of neural activity

(2017) James J. Jun et al.   NATURE

Enhanced moisture barrier performance for ALD-encapsulated OLEDs by introducing an organic protective layer

(2017) Lei Wang et al.   Journal of Materials Chemistry C

Thin, Transferred Layers of Silicon Dioxide and Silicon Nitride as Water and Ion Barriers for Implantable Flexible Electronic Systems

(2017) Enming Song et al.   Advanced Electronic Materials

Glial responses to implanted electrodes in the brain

(2017) Joseph W. Salatino et al.   Nature Biomedical Engineering

Design and demonstration of an intracortical probe technology with tunable modulus

(2016) Dustin M. Simon et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Long-term stability of intracortical recordings using perforated and arrayed Parylene sheath electrodes

(2016) Seth A Hara et al.   Journal of Neural Engineering

Correlations between histology and neuronal activity recorded by microelectrodes implanted chronically in the cerebral cortex

(2016) Douglas McCreery et al.   Journal of Neural Engineering

Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity

(2016) Thomas J Oxley et al.   NATURE BIOTECHNOLOGY

Ultrathin, transferred layers of thermally grown silicon dioxide as biofluid barriers for biointegrated flexible electronic systems

(2016) Hui Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interfacing Electronic and Ionic Charge Transport in Bioelectronics

(2016) David C. Martin et al.   ChemElectroChem

Boron-Doped Nanocrystalline Diamond Electrodes for Neural Interfaces: In vivo Biocompatibility Evaluation

(2016) María Alcaide et al.   Frontiers in Neuroscience

Organic electronics for high-resolution electrocorticography of the human brain

(2016) D. Khodagholy et al.   Science Advances

Brain Tissue Responses to Neural Implants Impact Signal Sensitivity and Intervention Strategies

(2015) Takashi D. Y. Kozai et al.   ACS Chemical Neuroscience

Transfer Printing of Metallic Microstructures on Adhesion-Promoting Hydrogel Substrates

(2015) Haosheng Wu et al.   ADVANCED MATERIALS

BBB leakage, astrogliosis, and tissue loss correlate with silicon microelectrode array recording performance

(2015) Nicholas F. Nolta et al.   BIOMATERIALS

Parylene-based flexible neural probes with PEDOT coated surface for brain stimulation and recording

(2015) V. Castagnola et al.   BIOSENSORS & BIOELECTRONICS

Insertion of linear 8.4μm diameter 16 channel carbon fiber electrode arrays for single unit recordings

(2015) Paras R Patel et al.   Journal of Neural Engineering

Electronic dura mater for long-term multimodal neural interfaces

(2015) I. R. Minev et al.   SCIENCE

Elastomeric and soft conducting microwires for implantable neural interfaces

(2015) Christi L. Kolarcik et al.   Soft Matter

Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: new challenges and opportunities

(2015) Takashi D. Y. Kozai et al.   Journal of Materials Chemistry B

Effects of caspase-1 knockout on chronic neural recording quality and longevity: Insight into cellular and molecular mechanisms of the reactive tissue response

(2014) Takashi D.Y. Kozai et al.   BIOMATERIALS

NeuroGrid: recording action potentials from the surface of the brain

(2014) Dion Khodagholy et al.   NATURE NEUROSCIENCE

Photocrosslinkable biodegradable elastomers based on cinnamate-functionalized polyesters

(2013) Congcong Zhu et al.   Acta Biomaterialia

Reconfigurable Biodegradable Shape-Memory Elastomers via Diels–Alder Coupling

(2013) Chi Ninh et al.   BIOMACROMOLECULES

An all-diamond, hermetic electrical feedthrough array for a retinal prosthesis

(2013) Kumaravelu Ganesan et al.   BIOMATERIALS

Thiol-ene/acrylate substrates for softening intracortical electrodes

(2013) Taylor Ware et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Topographic substrates as strain relief features in stretchable organic thin film transistors

(2013) Haosheng Wu et al.   ORGANIC ELECTRONICS

Ultrasmall implantable composite microelectrodes with bioactive surfaces for chronic neural interfaces

(2012) Takashi D. Yoshida Kozai et al.   NATURE MATERIALS

History, Applications, and Mechanisms of Deep Brain Stimulation

(2012) Svjetlana Miocinovic et al.   JAMA Neurology

Highly Conformable Conducting Polymer Electrodes for In Vivo Recordings

(2011) Dion Khodagholy et al.   ADVANCED MATERIALS

Biodegradable Elastomers for Tissue Engineering and Cell-Biomaterial Interactions

(2011) Christopher J. Bettinger   MACROMOLECULAR BIOSCIENCE

Biodegradable xylitol-based elastomers: In vivo behavior and biocompatibility

(2010) Joost P. Bruggeman et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Reduction of neurovascular damage resulting from microelectrode insertion into the cerebral cortex usingin vivotwo-photon mapping

(2010) T D Y Kozai et al.   Journal of Neural Engineering

Organic Thin-Film Transistors Fabricated on Resorbable Biomaterial Substrates

(2009) Christopher J. Bettinger et al.   ADVANCED MATERIALS

Design and fabrication of a polyimide-based microelectrode array: Application in neural recording and repeatable electrolytic lesion in rat brain

(2009) You-Yin Chen et al.   JOURNAL OF NEUROSCIENCE METHODS

Encapsulation of organic light-emitting devices using a perfluorinated polymer

(2008) J. Granstrom et al.   APPLIED PHYSICS LETTERS

Biodegradable poly(polyol sebacate) polymers

(2008) Joost P. Bruggeman et al.   BIOMATERIALS

Amino alcohol-based degradable poly(ester amide) elastomers

(2008) Christopher J. Bettinger et al.   BIOMATERIALS

Encapsulation of an Integrated Neural Interface Device With Parylene C

(2008) Jui-Mei Hsu et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

In vitroandin vivodegradation of poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate) elastomers

(2008) Christopher J. Bettinger et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Accordion-like honeycombs for tissue engineering of cardiac anisotropy

(2008) George C. Engelmayr et al.   NATURE MATERIALS

Nanofabricated Collagen-Inspired Synthetic Elastomers for Primary Rat Hepatocyte Culture

(2008) Christopher J. Bettinger et al.   TISSUE ENGINEERING PART A

Demonstration of cortical recording using novel flexible polymer neural probes

(2007) André Mercanzini et al.   SENSORS AND ACTUATORS A-PHYSICAL