Electroacupuncture alleviates polycystic ovary syndrome-like symptoms through improving insulin resistance, mitochondrial dysfunction, and endoplasmic reticulum stress via enhancing autophagy in rats

Mitochondrial Dysfunction in Polycystic Ovary Syndrome

(2020) Xin Zeng et al.   DNA AND CELL BIOLOGY

Acupuncture or metformin to improve insulin resistance in women with polycystic ovary syndrome: study protocol of a combined multinational cross sectional case-control study and a randomised controlled trial

(2019) Elisabet Stener-Victorin et al.   BMJ Open

Efficacy of electroacupuncture in regulating the imbalance of AMH and FSH to improve follicle development and hyperandrogenism in PCOS rats

(2019) Yin Shi et al.   BIOMEDICINE & PHARMACOTHERAPY

The role of androgen in autophagy of granulosa cells from PCOS

(2019) Xiaoxue Li et al.   GYNECOLOGICAL ENDOCRINOLOGY

Activation of CaMKKβ-AMPK-mTOR pathway is required for autophagy induction by β,β-dimethylacrylshikonin against lung adenocarcinoma cells

(2019) Haibing Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The efficacy of Tung’s acupuncture for sex hormones in polycystic ovary syndrome: A randomized controlled trial

(2019) Yu Cao et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation

(2019) Scott Frendo-Cumbo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manual acupuncture for the infertile female with polycystic ovary syndrome (PCOS): study protocol for a randomized sham-controlled trial

(2019) Qiao Wang et al.   Trials

The role of mTOR in ovarian cancer, polycystic ovary syndrome and ovarian aging

(2018) Jin Liu et al.   CLINICAL ANATOMY

Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of polycystic ovary syndrome

(2018) Xi Song et al.   Oncotarget

A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome

(2018) Milana Kokosar et al.   Scientific Reports

Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity

(2018) Soh Yamamoto et al.   Cell Reports

Effects of four weeks intermittent hypoxia intervention on glucose homeostasis, insulin sensitivity, GLUT4 translocation, insulin receptor phosphorylation, and Akt activity in skeletal muscle of obese mice with type 2 diabetes

(2018) Yun Wang et al.   PLoS One

Electroacupuncture Preconditioning Improves Myocardial Infarction Injury via Enhancing AMPK-Dependent Autophagy in Rats

(2018) Qing Zeng et al.   Biomed Research International

Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

(2018) Jinjin Cai et al.   Cell Reports

Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte–endothelium interactions in PCOS

(2017) Celia Bañuls et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Impact of mitochondrial DNA copy number and displacement loop alterations on polycystic ovary syndrome risk in south Indian women

(2017) Tumu Venkat Reddy et al.   MITOCHONDRION

Downregulation of autophagy gene expression in endometria from women with polycystic ovary syndrome

(2017) Mirjana Sumarac-Dumanovic et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

(2017) Andrey V. Cybulsky   Nature Reviews Nephrology

Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis

(2017) Nozomi Takahashi et al.   Scientific Reports

Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders

(2016) Yu Cai et al.   Autophagy

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited

(2016) Robert L. Rosenfield et al.   ENDOCRINE REVIEWS

ER Stress and Autophagy

(2015) W. Lee et al.   CURRENT MOLECULAR MEDICINE

Circulating gonadotropins and ovarian adiponectin system are modulated by acupuncture independently of sex steroid or β-adrenergic action in a female hyperandrogenic rat model of polycystic ovary syndrome

(2015) Manuel Maliqueo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mitochondrial Dysfunction and Autophagy in Hepatic Ischemia/Reperfusion Injury

(2015) Kristina L. Go et al.   Biomed Research International

Enhanced insulin sensitivity and acute regulation of metabolic genes and signaling pathways after a single electrical or manual acupuncture session in female insulin-resistant rats

(2014) Anna Benrick et al.   ACTA DIABETOLOGICA

Acupuncture for ovulation induction in polycystic ovary syndrome: a randomized controlled trial

(2013) Julia Johansson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp

(2013) N. K. Stepto et al.   HUMAN REPRODUCTION

Effects of acupuncture and exercise on insulin sensitivity, adipose tissue characteristics, and markers of coagulation and fibrinolysis in women with polycystic ovary syndrome: secondary analyses of a randomized controlled trial

(2011) Elisabet Stener-Victorin et al.   FERTILITY AND STERILITY

Polycystic ovary syndrome: etiology, pathogenesis and diagnosis

(2011) Mark O. Goodarzi et al.   Nature Reviews Endocrinology

Autophagy in nonalcoholic steatohepatitis

(2011) Muhammad Amir et al.   Expert Review of Gastroenterology & Hepatology

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Metabolic features of the reproductive phenotypes of polycystic ovary syndrome

(2009) Lisa Moran et al.   HUMAN REPRODUCTION UPDATE

Low-Frequency Electro-Acupuncture and Physical Exercise Improve Metabolic Disturbances and Modulate Gene Expression in Adipose Tissue in Rats with Dihydrotestosterone-Induced Polycystic Ovary Syndrome

(2008) Louise Mannerås et al.   ENDOCRINOLOGY

Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction, achievement of pregnancy, and live birth in Asian women with polycystic ovary syndrome: a randomized controlled trial

(2008) Murizah Mohd Zain et al.   FERTILITY AND STERILITY