In vitro and in vivo evaluation of the radiosensitizing effect of a selective FGFR inhibitor (JNJ-42756493) for rectal cancer

Phase I Dose-Escalation Study of JNJ-42756493, an Oral Pan–Fibroblast Growth Factor Receptor Inhibitor, in Patients With Advanced Solid Tumors

(2015) Josep Tabernero et al.   JOURNAL OF CLINICAL ONCOLOGY

FGFR2 Is Amplified in the NCI-H716 Colorectal Cancer Cell Line and Is Required for Growth and Survival

(2014) Anjili Mathur et al.   PLoS One

Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models

(2013) H Zhang et al.   BRITISH JOURNAL OF CANCER

Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties

(2013) Françoise Bono et al.   CANCER CELL

FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547

(2013) L. Xie et al.   CLINICAL CANCER RESEARCH

Small molecule inhibition of fibroblast growth factor receptors in cancer

(2013) Guang Liang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

FGF Receptors: Cancer Biology and Therapeutics

(2013) Masaru Katoh et al.   MEDICINAL RESEARCH REVIEWS

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

(2012) P. R. Gavine et al.   CANCER RESEARCH

Targeting Fibroblast Growth Factor Receptor Signaling Inhibits Prostate Cancer Progression

(2012) S. Feng et al.   CLINICAL CANCER RESEARCH

Molecular Pathways: Fibroblast Growth Factor Signaling: A New Therapeutic Opportunity in Cancer

(2012) A. N. Brooks et al.   CLINICAL CANCER RESEARCH

Fibroblast Growth Factor Receptor 2 IIIc as a Therapeutic Target for Colorectal Cancer Cells

(2012) Y. Matsuda et al.   MOLECULAR CANCER THERAPEUTICS

Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance

(2012) V Chell et al.   ONCOGENE

Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: A potential therapeutic target in colorectal cancer

(2011) Yoko Matsuda et al.   CANCER LETTERS

FGFR-4 Arg388 Enhances Prostate Cancer Progression via Extracellular Signal-Related Kinase and Serum Response Factor Signaling

(2011) W. Yu et al.   CLINICAL CANCER RESEARCH

5-Aminoimidazole-4-Carboxamide Riboside Enhances Effect of Ionizing Radiation in PC3 Prostate Cancer Cells

(2011) Sofie F. Isebaert et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

FGF-dependent regulation of VEGF receptor 2 expression in mice

(2011) Masahiro Murakami et al.   JOURNAL OF CLINICAL INVESTIGATION

A Novel, Selective Inhibitor of Fibroblast Growth Factor Receptors That Shows a Potent Broad Spectrum of Antitumor Activity in Several Tumor Xenograft Models

(2011) G. Zhao et al.   MOLECULAR CANCER THERAPEUTICS

The current landscape of locally advanced rectal cancer

(2011) Mebea Aklilu et al.   Nature Reviews Clinical Oncology

Integration of Epidermal Growth Factor Receptor Inhibitors with Preoperative Chemoradiation

(2010) A. Debucquoy et al.   CLINICAL CANCER RESEARCH

Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer

(2009) Jordi Camps et al.   GENES CHROMOSOMES & CANCER

A Systematic Assessment of Radiation Dose Enhancement by 5-Aza-2′-Deoxycytidine and Histone Deacetylase Inhibitors in Head-and-Neck Squamous Cell Carcinoma

(2009) Harlinde De Schutter et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Molecular Response to Cetuximab and Efficacy of Preoperative Cetuximab-Based Chemoradiation in Rectal Cancer

(2009) Annelies Debucquoy et al.   JOURNAL OF CLINICAL ONCOLOGY

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Oncogene Addiction

(2008) I. B. Weinstein et al.   CANCER RESEARCH