Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of Alzheimer’s disease

Altered Levels of Homocysteine and Serum Natural Antioxidants Links Oxidative Damage to Alzheimer's Disease

(2018) Mustafa Cankurtaran et al.   JOURNAL OF ALZHEIMERS DISEASE

Memantine attenuates cell apoptosis by suppressing the calpain-caspase-3 pathway in an experimental model of ischemic stroke

(2017) Bin Chen et al.   EXPERIMENTAL CELL RESEARCH

A critical role of TRPM2 channel in Aβ42 -induced microglial activation and generation of tumor necrosis factor-α

(2017) Sharifah Alawieyah Syed Mortadza et al.   GLIA

Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress

(2016) Francesca Aiello et al.   ACS Chemical Neuroscience

Homocysteine induces PUMA-mediated mitochondrial apoptosis in SH-SY5Y cells

(2016) Yumi Jang et al.   AMINO ACIDS

Protective effect of transient receptor potential vanilloid subtype 1 (TRPV1) modulator, against behavioral, biochemical and structural damage in experimental models of Alzheimer's disease

(2016) Shalini Jayant et al.   BRAIN RESEARCH

Ovariectomy-Induced Mitochondrial Oxidative Stress, Apoptosis, and Calcium Ion Influx Through TRPA1, TRPM2, and TRPV1 Are Prevented by 17β-Estradiol, Tamoxifen, and Raloxifene in the Hippocampus and Dorsal Root Ganglion of Rats

(2016) Yener Yazğan et al.   MOLECULAR NEUROBIOLOGY

Modulation of Diabetes-Induced Oxidative Stress, Apoptosis, and Ca2+ Entry Through TRPM2 and TRPV1 Channels in Dorsal Root Ganglion and Hippocampus of Diabetic Rats by Melatonin and Selenium

(2016) Mehmet Cemal Kahya et al.   MOLECULAR NEUROBIOLOGY

The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels

(2016) Hasan Balaban et al.   MOLECULAR NEUROBIOLOGY

The interactive role of cannabinoid and vanilloid systems in hippocampal synaptic plasticity in rats

(2015) Lida Tahmasebi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to  -Amyloid Oligomer-Related Neurotoxicity and Memory Impairment

(2015) V. G. Ostapchenko et al.   JOURNAL OF NEUROSCIENCE

Protective effects of low molecular weight chondroitin sulfate on amyloid beta (Aβ)-induced damage in vitro and in vivo

(2015) Q. Zhang et al.   NEUROSCIENCE

Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: Involvement of TRPM2 and TRPV1 channels

(2015) İ.S. Övey et al.   NEUROSCIENCE

Localized TRPA1 channel Ca2+signals stimulated by reactive oxygen species promote cerebral artery dilation

(2015) Michelle N. Sullivan et al.   Science Signaling

Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain

(2015) Fatemeh Saffarzadeh et al.   SYNAPSE

Localized TRPA1 channel Ca2+signals stimulated by reactive oxygen species promote cerebral artery dilation

(2015) Michelle N. Sullivan et al.   Science Signaling

Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway

(2014) Hai-jun Wei et al.   ACTA PHARMACOLOGICA SINICA

Neuroprotection Induced by N-acetylcysteine and Selenium Against Traumatic Brain Injury-Induced Apoptosis and Calcium Entry in Hippocampus of Rat

(2014) Mustafa Nazıroğlu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats

(2014) Vahid Ghazizadeh et al.   METABOLIC BRAIN DISEASE

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotective Effects of NMDA and Group I Metabotropic Glutamate Receptor Antagonists Against Neurodegeneration Induced by Homocysteine in Rat Hippocampus: In Vivo Study

(2013) F. Yeganeh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat

(2013) Michael R. Due et al.   JOURNAL OF NEUROCHEMISTRY

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation

(2012) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

Role of Oxidative Stress and Ca2+ Signaling on Molecular Pathways of Neuropathic Pain in Diabetes: Focus on TRP Channels

(2012) Mustafa Nazıroğlu et al.   NEUROCHEMICAL RESEARCH

Effects of Selenium on Calcium Signaling and Apoptosis in Rat Dorsal Root Ganglion Neurons Induced by Oxidative Stress

(2012) Abdülhadi Cihangir Uğuz et al.   NEUROCHEMICAL RESEARCH

Bimodal effects of cinnamaldehyde and camphor on mouse TRPA1

(2012) Yeranddy A. Alpizar et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons

(2012) Jillian C Belrose et al.   Molecular Brain

Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: a cross-talk between mtThiol, Ca2+, and ROS

(2011) Brijesh Kumar Singh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Melatonin Reduces Apoptosis Induced by Calcium Signaling in Human Leukocytes: Evidence for the Involvement of Mitochondria and Bax Activation

(2010) Javier Espino et al.   JOURNAL OF MEMBRANE BIOLOGY

Transient Receptor Potential Melastatin 2 Expression is Increased Following Experimental Traumatic Brain Injury in Rats

(2010) Naomi L. Cook et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Homocysteine and copper induce cellular apoptosis via caspase activation and nuclear translocation of apoptosis-inducing factor in neuronal cell line SH-SY5Y

(2010) Yoshimasa Hirashima et al.   NEUROSCIENCE RESEARCH

Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat

(2010) Amin Ataie et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells

(2009) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

Effects of antioxidants on calcium influx through TRPM2 channels in transfected cells activated by hydrogen peroxide

(2008) Mustafa Nazıroğlu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Effects of homocysteine on metabolic pathways in cultured astrocytes

(2008) Ying Jin et al.   NEUROCHEMISTRY INTERNATIONAL