Effect of preoperative chemoradiotherapy on the immunological status of rectal cancer patients

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer

(2019) Yojiro Hashiguchi et al.   International Journal of Clinical Oncology

Significance of tumor-infiltrating lymphocytes before and after neoadjuvant therapy for rectal cancer

(2018) Shinji Matsutani et al.   CANCER SCIENCE

Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations

(2018) Keiichi Hatakeyama et al.   Scientific Reports

Combined Radiotherapy and Anti–PD-L1 Antibody Synergistically Enhances Antitumor Effect in Non–Small Cell Lung Cancer

(2017) Xiaomei Gong et al.   Journal of Thoracic Oncology

Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6-mediated COX-2/PGE 2 /β-catenin signalling pathway

(2017) Dehai Che et al.   MOLECULAR IMMUNOLOGY

Robotic-assisted multivisceral resection for rectal cancer: short-term outcomes at a single center

(2017) H. Hino et al.   Techniques in Coloproctology

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

(2017) Keiichi Ohshima et al.   Scientific Reports

Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse

(2016) Tadashi Ashizawa et al.   CLINICAL CANCER RESEARCH

Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer

(2016) Joana Tato-Costa et al.   Clinical Colorectal Cancer

Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial

(2016) Yanhong Deng et al.   JOURNAL OF CLINICAL ONCOLOGY

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

(2016) Li-Ching Fan et al.   Oncotarget

Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial

(2015) Claus Rödel et al.   LANCET ONCOLOGY

Stromal contribution to the colorectal cancer transcriptome

(2015) Claudio Isella et al.   NATURE GENETICS

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

(2015) JING GUO et al.   ONCOLOGY REPORTS

SAAS-CNV: A Joint Segmentation Approach on Aggregated and Allele Specific Signals for the Identification of Somatic Copy Number Alterations with Next-Generation Sequencing Data

(2015) Zhongyang Zhang et al.   PLoS Computational Biology

Image Analyzer-Based Assessment of Tumor-Infiltrating T Cell Subsets and Their Prognostic Values in Colorectal Carcinomas

(2015) Younghoon Kim et al.   PLoS One

CD8+ and FOXP3+ Tumor-Infiltrating T Cells Before and After Chemoradiotherapy for Rectal Cancer

(2014) Eiji Shinto et al.   ANNALS OF SURGICAL ONCOLOGY

Epithelial-to-mesenchymal transition and the cancer stem cell phenotype: insights from cancer biology with therapeutic implications for colorectal cancer

(2014) V J Findlay et al.   CANCER GENE THERAPY

Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma

(2014) John C. Morris et al.   PLoS One

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years

(2012) Rolf Sauer et al.   JOURNAL OF CLINICAL ONCOLOGY

Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial

(2012) Ralf-Dieter Hofheinz et al.   LANCET ONCOLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epithelial mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapy

(2012) Aneel Bhangu et al.   SURGICAL ONCOLOGY-OXFORD

Nomograms for Predicting Local Recurrence, Distant Metastases, and Overall Survival for Patients With Locally Advanced Rectal Cancer on the Basis of European Randomized Clinical Trials

(2011) Vincenzo Valentini et al.   JOURNAL OF CLINICAL ONCOLOGY

Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor

(2011) Anna M Dahlin et al.   MODERN PATHOLOGY

Phase I/II Study of Ipilimumab for Patients With Metastatic Melanoma

(2008) Jeffrey S. Weber et al.   JOURNAL OF CLINICAL ONCOLOGY