AMP‐activated protein kinase activator AICAR attenuates hypoxia‐induced murine fetal growth restriction in part by improving uterine artery blood flow

AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathway

(2019) Bodokhsuren Tsogbadrakh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacological activation of peroxisome proliferator-activated receptor gamma (PPAR-γ) protects against hypoxia-associated fetal growth restriction

(2019) Sydney L. Lane et al.   FASEB JOURNAL

Increased uterine artery blood flow in hypoxic murine pregnancy is not sufficient to prevent fetal growth restriction

(2019) Sydney L Lane et al.   BIOLOGY OF REPRODUCTION

Activation of AMPK in Human Placental Explants Impairs Mitochondrial Function and Cellular Metabolism

(2018) Daphne Landau et al.   Reproductive Sciences

Clinicians should stop prescribing sildenafil for fetal growth restriction (FGR): comment from the STRIDER Consortium

(2018) K. M. Groom et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism

(2018) Jenni Määttä et al.   Scientific Reports

Novel roles of mechanistic target of rapamycin signaling in regulating fetal growth†

(2018) Madhulika B Gupta et al.   BIOLOGY OF REPRODUCTION

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

(2017) Rebecca C. Rabinovitch et al.   Cell Reports

Placental Hypoxia During Early Pregnancy Causes Maternal Hypertension and Placental Insufficiency in the Hypoxic Guinea Pig Model

(2016) L. P. Thompson et al.   BIOLOGY OF REPRODUCTION

Estrogen Activates AMP-Activated Protein Kinase in Human Endothelial Cells via ERβ/Ca2+/Calmodulin-Dependent Protein Kinase Kinase β Pathway

(2015) Songbai Yang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Principles and standards for reporting animal experiments inThe Journal of PhysiologyandExperimental Physiology

(2015) David Grundy   EXPERIMENTAL PHYSIOLOGY

Estradiol Regulates Dorsal Vagal Complex Signal Transduction Pathway Transcriptional Reactivity to the AMPK Activator 5-Aminoimidazole-4-Carboxamide-Riboside (AICAR)

(2015) Fahaad S. H. Alenazi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy

(2015) Hannah Matheson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hypoxia, AMPK activation and uterine artery vasoreactivity

(2015) K. L. Skeffington et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative Stress in Placenta: Health and Diseases

(2015) Fan Wu et al.   Biomed Research International

Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt−/− Mouse Model of Preeclampsia/Fetal Growth Restriction

(2015) Joanna L. Stanley et al.   Scientific Reports

Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates

(2014) Victoria H. J. Roberts et al.   FASEB JOURNAL

Metformin Improves Glucose Effectiveness, Not Insulin Sensitivity: Predicting Treatment Response in Women With Polycystic Ovary Syndrome in an Open-Label, Interventional Study

(2014) Cindy T. Pau et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

(2014) X. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Prevalence Estimates of Gestational Diabetes Mellitus in the United States, Pregnancy Risk Assessment Monitoring System (PRAMS), 2007–2010

(2014) Carla L. DeSisto et al.   Preventing Chronic Disease

AICAR administration ameliorates hypertension and angiogenic imbalance in a model of preeclampsia in the rat

(2013) Christopher T. Banek et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chronic Hypoxia Inhibits Pregnancy-Induced Upregulation of SK Ca Channel Expression and Function in Uterine Arteries

(2013) Ronghui Zhu et al.   HYPERTENSION

Effects of Resveratrol in Pregnancy Using Murine Models with Reduced Blood Supply to the Uterus

(2013) Rajan Poudel et al.   PLoS One

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

AMP-activated protein kinase activator AICAR acutely lowers blood pressure and relaxes isolated resistance arteries of hypertensive rats

(2012) Rebecca J. Ford et al.   JOURNAL OF HYPERTENSION

Maternal resveratrol treatment during pregnancy improves adverse fetal outcomes in a rat model of severe hypoxia

(2012) S.L. Bourque et al.   PLACENTA

AMPK Alpha 1-Induced RhoA Phosphorylation Mediates Vasoprotective Effect of Estradiol

(2011) Marion Gayard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelium-dependent vasorelaxation to the AMPK activator AICAR is enhanced in aorta from hypertensive rats and is NO and EDCF dependent

(2010) Rebecca J. Ford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants

(2010) Eric M. George et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Childbearing and Obesity in Women: Weight Before, During, and After Pregnancy

(2009) Erica P. Gunderson   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

In Vitro Assessment of Mouse Uterine and Fetoplacental Vascular Function

(2009) L.C. Kusinski et al.   Reproductive Sciences

Inflammation and Pregnancy

(2009) John R. Challis et al.   Reproductive Sciences

The Global Impact of Pre-eclampsia and Eclampsia

(2009) Lelia Duley   SEMINARS IN PERINATOLOGY

Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes

(2008) Takayuki Matsumoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

(2008) H. Boon et al.   DIABETOLOGIA