AICAR administration ameliorates hypertension and angiogenic imbalance in a model of preeclampsia in the rat
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Title
AICAR administration ameliorates hypertension and angiogenic imbalance in a model of preeclampsia in the rat
Authors
Keywords
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Volume 304, Issue 8, Pages H1159-H1165
Publisher
American Physiological Society
Online
2013-02-16
DOI
10.1152/ajpheart.00903.2012
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- Endothelium-dependent vasorelaxation to the AMPK activator AICAR is enhanced in aorta from hypertensive rats and is NO and EDCF dependent
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- AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise
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